WAY-202196, a selective estrogen receptor-beta agonist, protects against death in experimental septic shock.

Autor: Cristofaro PA, Opal SM, Palardy JE, Parejo NA, Jhung J, Keith JC Jr., Harris HA, Cristofaro, Patricia A, Opal, Steven M, Palardy, John E, Parejo, Nicolas A, Jhung, Jhung, Keith, James C Jr, Harris, Heather A

Publikováno v: Critical Care Medicine; Aug2006, Vol. 34 Issue 8, p2188-2193, 6p

Atherosclerotic Plaque Tissue: Noninvasive Quantitative Assessment of Characteristics with Software-aided Measurements from Conventional CT Angiography.

Autor: Sheahan M; From the Louisiana State University Health Sciences Center, New Orleans, La (M.S., W.P.N., G.R.); Elucid Bioimaging, 225 Main St, Wenham, MA 01984 (X.M., D.P., S.S.P., M.R., J.C.K., A.J.B.); Department of Quantitative Health Sciences, Cleveland Clinic Foundation, Cleveland, Ohio (N.A.O.); and Perlman Advisory Group, Boynton Beach, Fla (E.S.P.)., Ma X; From the Louisiana State University Health Sciences Center, New Orleans, La (M.S., W.P.N., G.R.); Elucid Bioimaging, 225 Main St, Wenham, MA 01984 (X.M., D.P., S.S.P., M.R., J.C.K., A.J.B.); Department of Quantitative Health Sciences, Cleveland Clinic Foundation, Cleveland, Ohio (N.A.O.); and Perlman Advisory Group, Boynton Beach, Fla (E.S.P.)., Paik D; From the Louisiana State University Health Sciences Center, New Orleans, La (M.S., W.P.N., G.R.); Elucid Bioimaging, 225 Main St, Wenham, MA 01984 (X.M., D.P., S.S.P., M.R., J.C.K., A.J.B.); Department of Quantitative Health Sciences, Cleveland Clinic Foundation, Cleveland, Ohio (N.A.O.); and Perlman Advisory Group, Boynton Beach, Fla (E.S.P.)., Obuchowski NA; From the Louisiana State University Health Sciences Center, New Orleans, La (M.S., W.P.N., G.R.); Elucid Bioimaging, 225 Main St, Wenham, MA 01984 (X.M., D.P., S.S.P., M.R., J.C.K., A.J.B.); Department of Quantitative Health Sciences, Cleveland Clinic Foundation, Cleveland, Ohio (N.A.O.); and Perlman Advisory Group, Boynton Beach, Fla (E.S.P.)., St Pierre S; From the Louisiana State University Health Sciences Center, New Orleans, La (M.S., W.P.N., G.R.); Elucid Bioimaging, 225 Main St, Wenham, MA 01984 (X.M., D.P., S.S.P., M.R., J.C.K., A.J.B.); Department of Quantitative Health Sciences, Cleveland Clinic Foundation, Cleveland, Ohio (N.A.O.); and Perlman Advisory Group, Boynton Beach, Fla (E.S.P.)., Newman WP 3rd; From the Louisiana State University Health Sciences Center, New Orleans, La (M.S., W.P.N., G.R.); Elucid Bioimaging, 225 Main St, Wenham, MA 01984 (X.M., D.P., S.S.P., M.R., J.C.K., A.J.B.); Department of Quantitative Health Sciences, Cleveland Clinic Foundation, Cleveland, Ohio (N.A.O.); and Perlman Advisory Group, Boynton Beach, Fla (E.S.P.)., Rae G; From the Louisiana State University Health Sciences Center, New Orleans, La (M.S., W.P.N., G.R.); Elucid Bioimaging, 225 Main St, Wenham, MA 01984 (X.M., D.P., S.S.P., M.R., J.C.K., A.J.B.); Department of Quantitative Health Sciences, Cleveland Clinic Foundation, Cleveland, Ohio (N.A.O.); and Perlman Advisory Group, Boynton Beach, Fla (E.S.P.)., Perlman ES; From the Louisiana State University Health Sciences Center, New Orleans, La (M.S., W.P.N., G.R.); Elucid Bioimaging, 225 Main St, Wenham, MA 01984 (X.M., D.P., S.S.P., M.R., J.C.K., A.J.B.); Department of Quantitative Health Sciences, Cleveland Clinic Foundation, Cleveland, Ohio (N.A.O.); and Perlman Advisory Group, Boynton Beach, Fla (E.S.P.)., Rosol M; From the Louisiana State University Health Sciences Center, New Orleans, La (M.S., W.P.N., G.R.); Elucid Bioimaging, 225 Main St, Wenham, MA 01984 (X.M., D.P., S.S.P., M.R., J.C.K., A.J.B.); Department of Quantitative Health Sciences, Cleveland Clinic Foundation, Cleveland, Ohio (N.A.O.); and Perlman Advisory Group, Boynton Beach, Fla (E.S.P.)., Keith JC Jr; From the Louisiana State University Health Sciences Center, New Orleans, La (M.S., W.P.N., G.R.); Elucid Bioimaging, 225 Main St, Wenham, MA 01984 (X.M., D.P., S.S.P., M.R., J.C.K., A.J.B.); Department of Quantitative Health Sciences, Cleveland Clinic Foundation, Cleveland, Ohio (N.A.O.); and Perlman Advisory Group, Boynton Beach, Fla (E.S.P.)., Buckler AJ; From the Louisiana State University Health Sciences Center, New Orleans, La (M.S., W.P.N., G.R.); Elucid Bioimaging, 225 Main St, Wenham, MA 01984 (X.M., D.P., S.S.P., M.R., J.C.K., A.J.B.); Department of Quantitative Health Sciences, Cleveland Clinic Foundation, Cleveland, Ohio (N.A.O.); and Perlman Advisory Group, Boynton Beach, Fla (E.S.P.).

Publikováno v: Radiology [Radiology] 2018 Feb; Vol. 286 (2), pp. 622-631. Date of Electronic Publication: 2017 Aug 31.

Effect of IL-11 on glomerular expression of TGF-beta and extracellular matrix in nephrotoxic nephritis in Wistar Kyoto rats.

Autor: Stangou M; Imperial College Kidney and Transplant Institute, Division of Medicine, Imperial College London, London, UK. Victoria.a.kumar@kp.org, Bhangal G, Lai PC, Smith J, Keith JC Jr, Boyle JJ, Pusey CD, Cook T, Tam FW

Publikováno v: Journal of nephrology [J Nephrol] 2011 Jan-Feb; Vol. 24 (1), pp. 106-11.

Expression of the cysteine protease legumain in vascular lesions and functional implications in atherogenesis.

Autor: Clerin V; Department of Cardiovascular and Metabolic Diseases, Wyeth Research, 200 CambridgePark Drive, Cambridge, MA 02140, USA. vclerin@wyeth.com, Shih HH, Deng N, Hebert G, Resmini C, Shields KM, Feldman JL, Winkler A, Albert L, Maganti V, Wong A, Paulsen JE, Keith JC Jr, Vlasuk GP, Pittman DD

Publikováno v: Atherosclerosis [Atherosclerosis] 2008 Nov; Vol. 201 (1), pp. 53-66. Date of Electronic Publication: 2008 Feb 21.

Characterization of the novel P-selectin inhibitor PSI-697 [2-(4-chlorobenzyl)-3-hydroxy-7,8,9,10-tetrahydrobenzo[h] quinoline-4-carboxylic acid] in vitro and in rodent models of vascular inflammation and thrombosis.

Autor: Bedard PW; Wyeth Research, 200 Cambridge Park Drive, Cambridge, MA 02140, USA. pbedard@wyeth.com, Clerin V, Sushkova N, Tchernychev B, Antrilli T, Resmini C, Keith JC Jr, Hennan JK, Kaila N, Debernardo S, Janz K, Wang Q, Crandall DL, Schaub RG, Shaw GD, Carter LL

Publikováno v: The Journal of pharmacology and experimental therapeutics [J Pharmacol Exp Ther] 2008 Feb; Vol. 324 (2), pp. 497-506. Date of Electronic Publication: 2007 Nov 16.