Zobrazeno 1 - 10
of 129
pro vyhledávání: '"Keith J. Lookingland"'
Autor:
Jessica S. Fortin, Matthew J. Benskey, Keith J. Lookingland, Jon S. Patterson, Erin B. Howey, John L. Goudreau, Harold C. Schott
Publikováno v:
BMC Veterinary Research, Vol 16, Iss 1, Pp 1-8 (2020)
Abstract Background Pituitary pars intermedia dysfunction (PPID) develops slowly in aged horses as degeneration of hypothalamic dopaminergic neurons leads to proliferation of pars intermedia (PI) melanotropes through hyperplasia and adenoma formation
Externí odkaz:
https://doaj.org/article/05e9786de3ea4e928808505fd95b0b17
Autor:
Brittany M. Winner, Harue Zhang, McKenzie M. Farthing, Lalitha M. Karchalla, Keith J. Lookingland, John L. Goudreau
Publikováno v:
Frontiers in Aging Neuroscience, Vol 9 (2017)
Parkinson disease (PD) is prevalent in elderly individuals and is characterized by selective degeneration of nigrostriatal dopamine (NSDA) neurons. Interestingly, not all dopamine (DA) neurons are affected equally by PD and aging, particularly mesoli
Externí odkaz:
https://doaj.org/article/06cbfa6575cb4747b73aac51f10fac78
Autor:
John L. Goudreau, Jessica S. Fortin, Jon S. Patterson, Erin B. Howey, Matthew J. Benskey, Harold C. Schott, Keith J. Lookingland
Publikováno v:
BMC Veterinary Research, Vol 16, Iss 1, Pp 1-8 (2020)
BMC Veterinary Research
BMC Veterinary Research
Background Pituitary pars intermedia dysfunction (PPID) develops slowly in aged horses as degeneration of hypothalamic dopaminergic neurons leads to proliferation of pars intermedia (PI) melanotropes through hyperplasia and adenoma formation. Dopamin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f5a8c737c2ed06957e8a6ceda945cab
http://link.springer.com/article/10.1186/s12917-020-02565-3
http://link.springer.com/article/10.1186/s12917-020-02565-3
Autor:
James J. Galligan, John L. Goudreau, David Fried, Keith J. Lookingland, Kevin Parikh, Barbara L. F. Kaplan, Tyrell J. Simkins
Publikováno v:
Journal of Neuroimmune Pharmacology. 11:669-679
The spleen is a visceral organ that contracts during hypoxia to expel erythrocytes and immune cells into the circulation. Spleen contraction is under the control of noradrenergic sympathetic innervation. The activity of noradrenergic neurons terminat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fee656a3d4a82eba0db14889208b9ff
https://doi.org/10.1007/s11481-016-9689-2
https://doi.org/10.1007/s11481-016-9689-2
Autor:
John L. Goudreau, Chelsea T. Tiernan, Keith J. Lookingland, William D. Atchison, Ethan A. Edwin
Publikováno v:
Toxicological Sciences. 133:125-132
The purpose of this study was to characterize methylmercury (MeHg)–induced dopamine (DA) release from undifferentiated pheochromocytoma (PC12) cells and to examine the potential role for DA synthesis in this process. MeHg caused a significant incre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f4b1d5ba02a8a4cddb3556cc46a60a2
https://doi.org/10.1093/toxsci/kft025
https://doi.org/10.1093/toxsci/kft025
Parkinson disease (PD) is characterized by progressive neuronal degeneration, in particular nigrostriatal dopamine (NSDA) neurons and consequent deficits in movement. In mice and non-human primates, NSDA neurons preferentially degenerate following ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::132a408088390c406ac527a1634543c3
https://europepmc.org/articles/PMC5035640/
https://europepmc.org/articles/PMC5035640/
Autor:
Tyrell J, Simkins, David, Fried, Kevin, Parikh, James J, Galligan, John L, Goudreau, Keith J, Lookingland, Barbara L F, Kaplan
Publikováno v:
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. 11(4)
The spleen is a visceral organ that contracts during hypoxia to expel erythrocytes and immune cells into the circulation. Spleen contraction is under the control of noradrenergic sympathetic innervation. The activity of noradrenergic neurons terminat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::860c43fe7d8a0f2e44eaf43d650a4a79
https://pubmed.ncbi.nlm.nih.gov/27287619
https://pubmed.ncbi.nlm.nih.gov/27287619
Autor:
Seung-Hoon Baek, Bahareh Behrouz, Johan Sunryd, Marianne Huebner, Samuel S. Pappas, John L. Goudreau, Keith J. Lookingland, Matthew J. Benskey
Publikováno v:
NeuroToxicology. 33:321-331
Hypothalamic tuberoinfundibular dopamine (TIDA) neurons remain unaffected in Parkinson disease (PD) while there is significant degeneration of midbrain nigrostriatal dopamine (NSDA) neurons. A similar pattern of susceptibility is observed in acute an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::788aed5d83011a9c067f0a90ed09991d
https://doi.org/10.1016/j.neuro.2012.02.001
https://doi.org/10.1016/j.neuro.2012.02.001
Publikováno v:
Neuropharmacology. 61:614-621
Dopamine (DA) neurons of the A11 diencephalospinal system represent the sole source of DA innervation to the spinal cord in mice, serving neuromodulatory roles in the processing of nociceptive input and movement. These neurons originate in the dorso-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4037cd9a947f15812e27b9d178acc3a3
https://doi.org/10.1016/j.neuropharm.2011.05.002
https://doi.org/10.1016/j.neuropharm.2011.05.002
Autor:
Wilson K. Rumbeiha, Margaret Johnson, Tyrell J. Simkins, Keith J. Lookingland, John L. Goudreau, Andreas F. Lehner, Kelly L. Janis
Publikováno v:
Toxicology Mechanisms and Methods. 21:171-182
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) is widely used as a neurotoxin in several models of Parkinson's disease in mice. MPTP is metabolized to 1-methyl-4-phenylpyridinium (MPP(+)), which is a mitochondrial toxicant of central dopamine (D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3b92673c2f5e2fc73d01a02158dbe7d
https://doi.org/10.3109/15376516.2010.538753
https://doi.org/10.3109/15376516.2010.538753