Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Keith J. Cross"'
Autor:
Abu Sayeed M. Mahmud, Christine A. Seers, N. Laila Huq, Lianyi Zhang, Catherine A. Butler, Caroline Moore, Keith J. Cross, Eric C. Reynolds
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract The Arg-specific gingipains of Porphyromonas gingivalis RgpA and RgpB have 97% identical sequences in their catalytic domains yet their propeptides are only 76% identical. RgpA isolates as a proteinase–adhesin complex (HRgpA) which hinders
Externí odkaz:
https://doaj.org/article/62373cb149f64e4582bd5da8e3e92f8e
Publikováno v:
Journal of Oral Microbiology, Vol 13, Iss 1 (2021)
Background: The cell-surface cysteine proteinases RgpA, RgpB (Arg-gingipain), and Kgp (Lys-gingipain) are major virulence factors of P. gingivalis, a keystone pathogen in the development of destructive periodontal disease. The gingipains function as
Externí odkaz:
https://doaj.org/article/bca681ae1ef24739a5c036c87de9cb02
Autor:
Noorjahan Laila Huq, Helen Myroforidis, Keith J. Cross, David P. Stanton, Paul D. Veith, Brent R. Ward, Eric C. Reynolds
Publikováno v:
International Journal of Molecular Sciences, Vol 17, Iss 6, p 915 (2016)
The repair of early dental caries lesions has been demonstrated by the application of the remineralisation technology based on casein phosphopeptide-stabilised amorphous calcium phosphate complexes (CPP–ACP). These complexes consist of an amorphous
Externí odkaz:
https://doaj.org/article/639137b29f144ed89406db88b50405f8
Publikováno v:
Journal of Oral Microbiology
article-version (VoR) Version of Record
Journal of Oral Microbiology, Vol 13, Iss 1 (2021)
article-version (VoR) Version of Record
Journal of Oral Microbiology, Vol 13, Iss 1 (2021)
Background: The cell-surface cysteine proteinases RgpA, RgpB (Arg-gingipain), and Kgp (Lys-gingipain) are major virulence factors of P. gingivalis, a keystone pathogen in the development of destructive periodontal disease. The gingipains function as
Autor:
N. Laila Huq, Keith J. Cross, Christine A. Seers, Yu-Yen Chen, Eric C. Reynolds, Paul D. Veith, Dhana G. Gorasia, Lianyi Zhang
Publikováno v:
Journal of proteome research. 17(8)
Porphyromonas gingivalis is a keystone periodontal pathogen that has been associated with autoimmune disorders. The cell surface proteases Lys-gingipain (Kgp) and Arg-gingipains (RgpA and RgpB) are major virulence factors, and their proteolytic activ
Autor:
Glen Walker, Peiyan Shen, N. Laila Huq, Bill Madytianos, Coralie Reynolds, Eric C. Reynolds, Li-Ming Bhutta, Yi Yuan, Keith J. Cross, David P. Stanton, Boon Loh, Sarah Peterson
Publikováno v:
Biomineralization ISBN: 9789811310010
Casein phosphopeptides derived from tryptic digests of milk caseins spontaneously assemble with calcium and phosphate ions at high pH to form casein phosphopeptide-amorphous calcium phosphate complexes (CPP-ACP). These complexes have been shown to be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::921cb551c0f4f55b214a492110c3fecd
https://doi.org/10.1007/978-981-13-1002-7_23
https://doi.org/10.1007/978-981-13-1002-7_23
Molecular Interactions of Peptide Encapsulated Calcium Phosphate Delivery Vehicle at Enamel Surfaces
Autor:
Eric C. Reynolds, Helen Myroforidis, NL Huq, Yu-Yen Chen, Brent R. Ward, Keith J. Cross, David P. Stanton
Publikováno v:
Biomineralization ISBN: 9789811310010
Phosphorylated peptides derived from milk caseins, known as casein phosphopeptides (CPP), self-assemble and encapsulate the calcium and phosphate mineral in the form of amorphous calcium phosphate (ACP), thus forming CPP-ACP nanocomplexes that are no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b4ba3ebbf9f81560e9cab4dad853af6
https://doi.org/10.1007/978-981-13-1002-7_24
https://doi.org/10.1007/978-981-13-1002-7_24
Autor:
Belinda J. Michell, Christine A. Seers, Susanne C. Feil, Keith J. Cross, Michael W. Parker, Michael A. Gorman, Eric C. Reynolds, N. Laila Huq
Publikováno v:
Protein Science. 24:162-166
The oral pathogen Porphyromonas gingivalis is a keystone pathogen in the development of chronic periodontitis. Gingipains, the principle virulence factors of P. gingivalis are multidomain, cell-surface proteins containing a cysteine protease domain.
Autor:
Simon Gladman, Steven M. Cleal, Eric C. Reynolds, Christine A. Seers, Stuart G. Dashper, Dieter M. Bulach, P. Scott Chandry, Keith J. Cross, Torsten Seemann, Helen L. Mitchell
Publikováno v:
Frontiers in Microbiology
Porphyromonas gingivalis is a keystone pathogen of chronic periodontitis. The virulence of P. gingivalis is reported to be strain related and there are currently a number of strain typing schemes based on variation in capsular polysaccharide, the maj
Publikováno v:
Molecular Oral Microbiology. 30:87-96
Some amino acids are more energetically costly to synthesize de novo, therefore many microbes have evolved to regulate the metabolic expenditure of the cell and reduce the energy burden of extracellular unrecyclable proteins. Several oral bacterial s