Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Keith Hillier"'
Autor:
Keith Hillier
Publikováno v:
Eicosanoids in Reproduction ISBN: 9781315150949
Eicosanoids in Reproduction
Eicosanoids in Reproduction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b69421fbf2fdb0c8de58597dcc24e0d4
https://doi.org/10.1201/9781315150949-7
https://doi.org/10.1201/9781315150949-7
Autor:
Keith Hillier, James Jupp, David R. Fine, Daniel H. Elliott, Angelica Cazaly, Penny Johnson, Adrian C Bateman, John F. Penrose, Anthony P. Sampson
Publikováno v:
Inflammatory Bowel Diseases. 13:537-546
Leukotrienes derived from the 5-lipoxygenase pathway are proinflammatory lipid mediators that possibly play a role in inflammatory bowel diseases. The expression of 5-lipoxygenase pathway proteins has not previously been examined in colonic mucosa in
Publikováno v:
British Journal of Pharmacology. 123:231-236
We have investigated the effects of platelet-activating factor (PAF), an endogenous mediator of inflammation, on ion transport and prostaglandin synthesis in the human isolated colon. Application of PAF to the serosal surface of human colonic mucosa
Publikováno v:
Biochemical Pharmacology. 53:1323-1332
The biochemical properties of the phospholipase A2 (PLA2) found in the 100,000 x g centrifugate cytosol or particulate fractions of human colonic mucosa have been investigated using both deoxycholate-solubilized and Escherichia coli (E. coli) phospho
Autor:
Caroline B. Appleyard, Keith Hillier
Publikováno v:
Clinical Science. 88:713-717
1. Platelet-activating factor can be synthesized by two distinct biochemical pathways and is degraded by a number of enzymes, the first step of which is deacetylation by a specific acetyl hydrolase. 2. The biochemical pathway of platelet-activating f
Publikováno v:
British Journal of Pharmacology. 115:172-176
1. In isolated circular smooth muscle strips of human colon 5-hydroxytryptamine (5-HT) produced a concentration-related inhibition of spontaneous motility. 2. The azabicycloalkyl benzimidazolones, BIMU 8 and BIMU 1, which have 5-HT4 receptor stimulan
Publikováno v:
British Journal of Pharmacology. 113:143-150
1. Experiments were carried out to characterize pharmacologically the 5-hydroxytryptamine (5-HT) receptor types which mediate inhibition of spontaneous contractions of the intertaenial circular muscle in human isolated colon. 2. 5-HT caused a reprodu
Autor:
Caroline B. Appleyard, Keith Hillier
Publikováno v:
Biochemical Pharmacology. 43:2503-2509
The catabolism of platelet-activating factor (PAF) and lyso PAF by a supernatant fraction of human colon mucosa homogenates has been studied in vitro . PAF is initially catabolized to lyso PAF by mucosal enzymes via removal of its acetyl group. Incub
Autor:
Keith Hillier
Publikováno v:
xPharm: The Comprehensive Pharmacology Reference ISBN: 9780080552323
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a7acfadfc874e21e3d7b80657445e9f
https://doi.org/10.1016/b978-008055232-3.62488-2
https://doi.org/10.1016/b978-008055232-3.62488-2