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pro vyhledávání: '"Keith H. Byington"'
Autor:
Keith H. Byington
Publikováno v:
Life Sciences. 63:41-44
Incubation of tritium labeled dopamine (3HDA) with a preparation of rat heart or bovine serum albumin in vitro, or the intravenous injection of 3HDA to rats, gives acid insoluble, tritium labeled material that is slowly converted to soluble labeled m
Autor:
Keith H. Byington
Publikováno v:
Biochemical Pharmacology. 49:119-122
The adenylyl cyclase activity of homogenates of striatal tissue from rat brain has been used as a model to test the hypothesis that the products of the reaction of polyphenols with ferric iron compounds are toxic. Dopamine (DA), at levels that stimul
Publikováno v:
European Journal of Pharmacology. 117:43-50
We have synthesized and characterized p-azidoclonidine (AZC) as a putative alpha 2-adrenoceptor photoaffinity label. [3H]AZC demonstrated high affinity (KD = 11.8 +/- 2.5 nM), saturability (Bmax = 171 +/- 21 fmol/mg protein), stereo-specificity, and
Publikováno v:
Toxicology and Applied Pharmacology. 52:379-385
The interaction of triethyllead chloride with human and rat hemoglobin has been investigated using equilibrium dialysis. In addition the uptake of triethyllead by washed human and rat erythrocytes has been studied in vitro and the distribution of the
Publikováno v:
Biochemistry. 7:1596-1602
Publikováno v:
Journal of Biological Chemistry. 243:1589-1597
An oligomycin-sensitive adenosine triphosphatase complex has been purified from bovine heart mitochondria by ammonium sulfate fractionation in presence of bile salts. With the exception of flavin and a small amount of cytochromes b and c1 the prepara
Publikováno v:
Biochemical pharmacology. 29(18)
Autor:
Keith H. Byington, Roy A. Henry
Publikováno v:
Biochemical pharmacology. 25(20)
Compounds having three carbon—germanium, carbon—tin or carbon—lead bonds were found to be effective inhibitors of rat liver glutathione- S -aryltransferase activity with K i , values in the μM range. Classical competitive inhibition was observ
Publikováno v:
Toxicology and applied pharmacology. 27(2)
Triphenyltin chloride caused the rapid hemolysis of dog, hog, rabbit, or rat blood; however, human blood was resistant to hemolysis by triphenyltin chloride. Trialkytin compounds with alkyl groups having 3–6 carbon atoms were hemolytic to both huma
Autor:
Keith H. Byington
Publikováno v:
Life sciences. 40(21)
The 3 or 4 phosphate ester of dopamine (PD) was hydrolyzed by homogenates of rat tissues to give inorganic phosphate (Pi) and dopamine. The rate of hydrolysis of PD by kidney homogenates was increased by exogenous MgCl 2 but not CaCl 2 or KCl. The ac