Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Keith G. Kozminski"'
Autor:
Shubha A Dighe, Keith G Kozminski
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e99494 (2014)
The activation and localization of the Rho-family GTPase Cdc42p at one pole of a cell is necessary for maintaining an axis of polarized growth in many animal and fungal cells. How the asymmetric distribution of this key regulator of polarized morphog
Externí odkaz:
https://doaj.org/article/c38a617c4e814b5fa0154fcb2f7cb129
Autor:
Sukanya Basu, Keith G. Kozminski, Boyang Li, Paul J. Cullen, Garrett Kimble, Beatriz González
Publikováno v:
Molecular Biology of the Cell
Rho GTPases regulate cell polarity and signal transduction pathways to control morphogenetic responses in different settings. In yeast, the Rho GTPase Cdc42p regulates cell polarity, and through the p21-activated kinase Ste20p, Cdc42p also regulates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a23e234313d174e32a2e79a9ae67af57
Autor:
Keith G. Kozminski
Publikováno v:
Molecular Biology of the Cell
New scientific frontiers and emerging technologies within the life sciences pose many global challenges to society. Big Data is a premier example, especially with respect to individual, national, and international security. Here a Special Agent of th
Autor:
Richard J, Smindak, Lindsay A, Heckle, Supraja S, Chittari, Marissa A, Hand, Dylan M, Hyatt, Grace E, Mantus, William A, Sanfelippo, Keith G, Kozminski
Publikováno v:
Journal of cell science. 130(22)
Polarized exocytosis is an essential process in many organisms and cell types for correct cell division or functional specialization. Previous studies established that homologs of the oxysterol-binding protein (OSBP) in
Autor:
Jesper Johansen, Giselle Duamel, Shubha Dighe, Christopher T. Beh, Gabriel Alfaro, Keith G. Kozminski
Publikováno v:
Traffic. 12:1521-1536
Oxysterol-binding protein (OSBP)-related protein Kes1/ Osh4p is implicated in nonvesicular sterol transfer between membranes in Saccharomyces cerevisiae. However, we found that Osh4p associated with exocytic vesicles that move from the mother cell in
Autor:
Giselle Duamel, Anant K. Menon, Christopher T. Beh, Michael C. Kersting, Keith G. Kozminski, David P. Sullivan, Gabriel Alfaro, Shubha Dighe
Publikováno v:
Molecular and Cellular Biochemistry. 326:9-13
Oxysterol-binding protein (OSBP) and OSBP-related proteins (ORPs) are a conserved family of soluble cytoplasmic proteins that can bind sterols, translocate between membrane compartments, and affect sterol trafficking. These properties make ORPs attra
Autor:
Elizabeth Angerman, Charles Boone, Hay-Oak Park, Laure Béven, Keith G. Kozminski, Amy Hin Yan Tong
Publikováno v:
Molecular Biology of the Cell
Molecular Biology of the Cell, American Society for Cell Biology, 2003, 14, pp.4958-4970
Molecular Biology of the Cell, American Society for Cell Biology, 2004, 15, pp.355A
Molecular Biology of the Cell, American Society for Cell Biology, 2003, 14, pp.4958-4970
Molecular Biology of the Cell, American Society for Cell Biology, 2004, 15, pp.355A
Polarized cell growth requires the coupling of a defined spatial site on the cell cortex to the apparatus that directs the establishment of cell polarity. In the budding yeast Saccharomyces cerevisiae, the Ras-family GTPase Rsr1p/Bud1p and its regula
Autor:
Keith G. Kozminski
Publikováno v:
Molecular Biology of the Cell
Intraflagellar transport is the rapid, bidirectional movement of protein complexes along the length of most eukaryotic cilia and flagella. Discovery of this intracellular process in Chlamydomonas reinhardtii 20 years ago led to a rapid discovery of c
Autor:
Erfei Bi, Wei Guo, Li-Lin Du, Keith G. Kozminski, Joshua H. Lipschutz, Peter Novick, Xiaoyu Zhang
Publikováno v:
Journal of Biological Chemistry. 276:46745-46750
Polarized delivery and incorporation of proteins and lipids to specific domains of the plasma membrane is fundamental to a wide range of biological processes such as neuronal synaptogenesis and epithelial cell polarization. The exocyst complex is spe
Autor:
Keith G. Kozminski, Kimberly M Yasutis
Publikováno v:
Cell cycle (Georgetown, Tex.). 12(10)
Entry into mitosis is regulated by a checkpoint at the boundary between the G2 and M phases of the cell cycle (G2/M). In many organisms, this checkpoint surveys DNA damage and cell size and is controlled by both the activation of mitotic cyclin-depen