Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Keith G. H. Dyke"'
Autor:
Simon R. Clarke, Keith G. H. Dyke
Publikováno v:
Microbiology. 147:803-810
The precise start points for transcription of the blaZ and of the blaRI/blaI genes of the Staphylococcus aureus beta-lactamase operon have been determined by primer extension analysis. Consequently the overlapping promoter sequences were deduced. Nor
Autor:
Keith G. H. Dyke, Simon R. Clarke
Publikováno v:
Journal of Antimicrobial Chemotherapy. 47:377-389
The repressor proteins BlaI and MecI bind similarly to the bla operator implicated in the regulation of beta-lactamase synthesis in Staphylococcus aureus. BlaI binds to two separate dyads but neither copper-phenanthroline footprinting nor dimethyl su
Publikováno v:
Infection and Immunity. 69:712-718
The atlC gene (1,485 bp), encoding an autolysin which binds fibronectin, and the ica operon, involved in biofilm formation, were isolated from the chromosome of an infectious isolate of Staphylococcus caprae and sequenced. AtlC (155 kDa) is similar t
Autor:
Ronald A. Skurray, Keith G. H. Dyke, S.P. Curnock, Brendon A. O’Rourke, Tracey Berg, Sumalee Apisiridej, Neville Firth
Publikováno v:
Journal of Bacteriology. 182:2170-2178
Based on structural and functional properties, three groups of large staphylococcal multiresistance plasmids have been recognized, viz., the pSK1 family, pSK41-like conjugative plasmids, and β-lactamase–heavy-metal resistance plasmids. Here we des
Publikováno v:
FEMS Microbiology Letters. 178:271-275
The proteolytic cleavage of BlaI was shown to correlate with beta-lactamase synthesis in Staphylococcus aureus. BlaI was found to be autoregulatory when expressed from the blaZ promoter. Insertion of a 10-bp linker into the SnaBI site of blaRI result
Publikováno v:
Plasmid. 40:238-242
The two Staphylococcus epidermidis plasmids pIP1629 (7.5 kb) and pIP1630 (14.4 kb) contain the vga gene conferring resistance to streptogramin A. All the sequences of pIP1629, except two of the four 22-nt iterons preceding the replication gene, were
Publikováno v:
Plasmid. 34:198-205
The plasmid pJ3356 confers high-level mupirocin resistance on a strain of Staphylococcus aureus isolated from a hospital. The plasmid also carries two copies of IS257. Recombination of an IS257-containing plasmid conferring erythromycin resistance, p
Autor:
Muhammad Sohail, Keith G. H. Dyke
Publikováno v:
Gene. 162:63-68
Site-specific recombination is thought to play an important role in the evolution of multi-resistant plasmids in bacteria, including the human pathogen Staphylococcus aureus (Sa) . A mechanism for site- and orientation-specific recombination between
Publikováno v:
FEMS Microbiology Letters. 127:165-170
The plasmid pI9789::Tn552 carries genes conferring resistance to penicillins and to cadmium, mercury and arsenate ions. The presence of Tn551 at one location in the chromosome of Staphylococcus aureus enhances the frequency of suppression of thermose
Publikováno v:
FEMS Microbiology Letters. 127:165-170
The plasmid pI9789::Tn552 carries genes conferring resistance to penicillins and to cadmium, mercury and arsenate ions. The presence of Tn551 at one location in the chromosome of Staphylococcus aureus enhances the frequency of suppression of thermose