Zobrazeno 1 - 10
of 158
pro vyhledávání: '"Keith G, Mansfield"'
Autor:
Alfred L. Garfall, Adam D. Cohen, Sandra P. Susanibar-Adaniya, Wei-Ting Hwang, Dan T. Vogl, Adam J. Waxman, Simon F. Lacey, Vanessa E. Gonzalez, Joseph A. Fraietta, Minnal Gupta, Irina Kulikovskaya, Lifeng Tian, Fang Chen, Natalka Koterba, Robert L. Bartoszek, Margaret Patchin, Rong Xu, Gabriela Plesa, Don L. Siegel, Andrea Brennan, Anne Marie Nelson, Regina Ferthio, Angela Cosey, Kim-Marie Shea, Rachel Leskowitz, Megan Four, Wesley V. Wilson, Fei Miao, Eric Lancaster, Beatriz M. Carreno, Gerald P. Linette, Elizabeth O. Hexner, Regina M. Young, Dexiu Bu, Keith G. Mansfield, Jennifer L. Brogdon, Carl H. June, Michael C. Milone, Edward A. Stadtmauer
Publikováno v:
Blood Cancer Discovery. 4:118-133
We conducted a phase I clinical trial of anti-BCMA chimeric antigen receptor T cells (CART-BCMA) with or without anti-CD19 CAR T cells (huCART19) in multiple myeloma (MM) patients responding to third- or later-line therapy (phase A, N = 10) or high-r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af15a4e58dc3d2eade0573800002170e
https://doi.org/10.1158/2643-3230.bcd-22-0074
https://doi.org/10.1158/2643-3230.bcd-22-0074
Autor:
Edward A. Stadtmauer, Michael C. Milone, Carl H. June, Jennifer L. Brogdon, Keith G. Mansfield, Dexiu Bu, Regina M. Young, Elizabeth O. Hexner, Gerald P. Linette, Beatriz M. Carreno, Eric Lancaster, Fei Miao, Wesley V. Wilson, Megan Four, Rachel Leskowitz, Kim-Marie Shea, Angela Cosey, Regina Ferthio, Anne Marie Nelson, Andrea Brennan, Don L. Siegel, Gabriela Plesa, Rong Xu, Margaret Patchin, Robert L. Bartoszek, Natalka Koterba, Fang Chen, Lifeng Tian, Irina Kulikovskaya, Minnal Gupta, Joseph A. Fraietta, Vanessa E. Gonzalez, Simon F. Lacey, Adam J. Waxman, Dan T. Vogl, Wei-Ting Hwang, Sandra P. Susanibar-Adaniya, Adam D. Cohen, Alfred L. Garfall
Supplemental tables: (1) Subject characteristics. (2) Cytogenetic profiles and high-risk features. (3) Prior treatment exposures and refractoriness. (4) CAR T cell product characteristics. (5) Products that did not meet target dose. (6) Adverse event
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a41bd0d88d5d4c7b561e5825c554cb6
https://doi.org/10.1158/2643-3230.22546220
https://doi.org/10.1158/2643-3230.22546220
Autor:
Edward A. Stadtmauer, Michael C. Milone, Carl H. June, Jennifer L. Brogdon, Keith G. Mansfield, Dexiu Bu, Regina M. Young, Elizabeth O. Hexner, Gerald P. Linette, Beatriz M. Carreno, Eric Lancaster, Fei Miao, Wesley V. Wilson, Megan Four, Rachel Leskowitz, Kim-Marie Shea, Angela Cosey, Regina Ferthio, Anne Marie Nelson, Andrea Brennan, Don L. Siegel, Gabriela Plesa, Rong Xu, Margaret Patchin, Robert L. Bartoszek, Natalka Koterba, Fang Chen, Lifeng Tian, Irina Kulikovskaya, Minnal Gupta, Joseph A. Fraietta, Vanessa E. Gonzalez, Simon F. Lacey, Adam J. Waxman, Dan T. Vogl, Wei-Ting Hwang, Sandra P. Susanibar-Adaniya, Adam D. Cohen, Alfred L. Garfall
We conducted a phase I clinical trial of anti-BCMA chimeric antigen receptor T cells (CART-BCMA) with or without anti-CD19 CAR T cells (huCART19) in multiple myeloma (MM) patients responding to third- or later-line therapy (phase A, N = 10) or high-r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80421cf85e910d57e6c55056f662dc98
https://doi.org/10.1158/2643-3230.c.6551123.v1
https://doi.org/10.1158/2643-3230.c.6551123.v1
Autor:
Tinya J. Abrams, Jason S. Damiano, Judith A. Abraham, Paul Kwon, Emma Lees, Nancy K. Pryer, Ursula Jeffry, Katherine G. Rendahl, Thomas Huber, Kathy Miller, Christie P. Fanton, Sylvie Lehmann, William R. Tschantz, GiNell Elliot, Rick Newcombe, Margaret E. McLaughlin, Jane Gu, Felipe C. Geyer, Majid Ghoddusi, Jean-Michel Rondeau, Keith G. Mansfield, Anu Connor, Chi Ying, Suzanna Clark, Angela Tam, Yan Tang, Christopher Karim, Daniel L. Menezes, Joseph A. D'Alessio, Qing Sheng
Figures S1, S2, s3, S4, Table S1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::657c2118ddc53bb94cc549cd76abf99c
https://doi.org/10.1158/1535-7163.22521895.v1
https://doi.org/10.1158/1535-7163.22521895.v1
Autor:
Emma Lees, William R. Sellers, Seth A. Ettenberg, Jeffrey A. Engelman, Francesco Hofmann, Juliet Williams, Hui Gao, Xiuxia Sun, Molly A. McShea, Kalli C. Catcott, Nicholas C. Yoder, Vivien W. Chan, Mary J. Janatpour, Jason E. Faris, Matthew J. Meyer, Aaron Bourret, Duc Nguyen, Markus Kurz, William R. Tschantz, Anne Serdakowski London, Tina Rubic-Schneider, Emily K. Meseck, Keith G. Mansfield, Meghan M. Flaherty, Jessica C. Piel, Artur Veloso, GiNell Elliott, Joel P. Wagner, Wei Jiang, Vladimir Capka, Ivana Liric Rajlic, Sanela Bilic, Tiancen Hu, Lance Ostrom, David Lee, Rebecca Mosher, Yeonju Shim, Pierric Prieur, Bruno Lafont, Clemens Dürr, Xiamei Zhang, Parmita Saxena, Xiao Li, Scott D. Collins, Carl U. Bialucha
This file describes supplementary material and methods used.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d44657d8d2fbce35e6a00e8c0ee3cc8
https://doi.org/10.1158/2159-8290.22531925
https://doi.org/10.1158/2159-8290.22531925
Autor:
Emma Lees, William R. Sellers, Seth A. Ettenberg, Jeffrey A. Engelman, Francesco Hofmann, Juliet Williams, Hui Gao, Xiuxia Sun, Molly A. McShea, Kalli C. Catcott, Nicholas C. Yoder, Vivien W. Chan, Mary J. Janatpour, Jason E. Faris, Matthew J. Meyer, Aaron Bourret, Duc Nguyen, Markus Kurz, William R. Tschantz, Anne Serdakowski London, Tina Rubic-Schneider, Emily K. Meseck, Keith G. Mansfield, Meghan M. Flaherty, Jessica C. Piel, Artur Veloso, GiNell Elliott, Joel P. Wagner, Wei Jiang, Vladimir Capka, Ivana Liric Rajlic, Sanela Bilic, Tiancen Hu, Lance Ostrom, David Lee, Rebecca Mosher, Yeonju Shim, Pierric Prieur, Bruno Lafont, Clemens Dürr, Xiamei Zhang, Parmita Saxena, Xiao Li, Scott D. Collins, Carl U. Bialucha
This file contains supplementary tables describing parameters for antitumor activity (T/C analyses), PK and protein crystallography.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c846a62ad61c836d71d14a89443dcfc
https://doi.org/10.1158/2159-8290.22531922.v1
https://doi.org/10.1158/2159-8290.22531922.v1
Autor:
Tinya J. Abrams, Jason S. Damiano, Judith A. Abraham, Paul Kwon, Emma Lees, Nancy K. Pryer, Ursula Jeffry, Katherine G. Rendahl, Thomas Huber, Kathy Miller, Christie P. Fanton, Sylvie Lehmann, William R. Tschantz, GiNell Elliot, Rick Newcombe, Margaret E. McLaughlin, Jane Gu, Felipe C. Geyer, Majid Ghoddusi, Jean-Michel Rondeau, Keith G. Mansfield, Anu Connor, Chi Ying, Suzanna Clark, Angela Tam, Yan Tang, Christopher Karim, Daniel L. Menezes, Joseph A. D'Alessio, Qing Sheng
The cell surface glycoprotein P-cadherin is highly expressed in a number of malignancies, including those arising in the epithelium of the bladder, breast, esophagus, lung, and upper aerodigestive system. PCA062 is a P-cadherin specific antibody–dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42af133f07879ce825ff1f600618e03a
https://doi.org/10.1158/1535-7163.c.6543214.v1
https://doi.org/10.1158/1535-7163.c.6543214.v1
Autor:
Emma Lees, William R. Sellers, Seth A. Ettenberg, Jeffrey A. Engelman, Francesco Hofmann, Juliet Williams, Hui Gao, Xiuxia Sun, Molly A. McShea, Kalli C. Catcott, Nicholas C. Yoder, Vivien W. Chan, Mary J. Janatpour, Jason E. Faris, Matthew J. Meyer, Aaron Bourret, Duc Nguyen, Markus Kurz, William R. Tschantz, Anne Serdakowski London, Tina Rubic-Schneider, Emily K. Meseck, Keith G. Mansfield, Meghan M. Flaherty, Jessica C. Piel, Artur Veloso, GiNell Elliott, Joel P. Wagner, Wei Jiang, Vladimir Capka, Ivana Liric Rajlic, Sanela Bilic, Tiancen Hu, Lance Ostrom, David Lee, Rebecca Mosher, Yeonju Shim, Pierric Prieur, Bruno Lafont, Clemens Dürr, Xiamei Zhang, Parmita Saxena, Xiao Li, Scott D. Collins, Carl U. Bialucha
This file contains the figure legends for supplementary figures S1-S7.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59c4eef9f089f00def2dc18a4bc3cd01
https://doi.org/10.1158/2159-8290.22531931.v1
https://doi.org/10.1158/2159-8290.22531931.v1
Autor:
Tinya J. Abrams, Jason S. Damiano, Judith A. Abraham, Paul Kwon, Emma Lees, Nancy K. Pryer, Ursula Jeffry, Katherine G. Rendahl, Thomas Huber, Kathy Miller, Christie P. Fanton, Sylvie Lehmann, William R. Tschantz, GiNell Elliot, Rick Newcombe, Margaret E. McLaughlin, Jane Gu, Felipe C. Geyer, Majid Ghoddusi, Jean-Michel Rondeau, Keith G. Mansfield, Anu Connor, Chi Ying, Suzanna Clark, Angela Tam, Yan Tang, Christopher Karim, Daniel L. Menezes, Joseph A. D'Alessio, Qing Sheng
Cell line sensitivity table
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69a00bb2e2018e033b09c776799bf3e3
https://doi.org/10.1158/1535-7163.22521889.v1
https://doi.org/10.1158/1535-7163.22521889.v1
Publikováno v:
Toxicologic pathology. 50(5)
CFZ533 (iscalimab) is a nondepleting anti-CD40 antibody intended for inhibition of transplant organ rejection and treatment of autoimmune diseases. In a safety assessment in rhesus monkeys, CFZ533 was administered for 13 weeks up to 150 mg/kg/week su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66fceef472135a8d26a1c1fc3699ec02
https://pubmed.ncbi.nlm.nih.gov/35730205
https://pubmed.ncbi.nlm.nih.gov/35730205