Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Keith E. Steele"'
Autor:
Claire Germain, Priyanka Devi-Marulkar, Samantha Knockaert, Jérôme Biton, Hélène Kaplon, Laïla Letaïef, Jérémy Goc, Agathe Seguin-Givelet, Dominique Gossot, Nicolas Girard, Pierre Validire, Marine Lefèvre, Diane Damotte, Marco Alifano, François M. Lemoine, Keith E. Steele, Jean-Luc Teillaud, Scott A. Hammond, Marie-Caroline Dieu-Nosjean
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The presence of tertiary lymphoid structures (TLS) in the tumor microenvironment is associated with better clinical outcome in many cancers. In non-small cell lung cancer (NSCLC), we have previously showed that a high density of B cells within TLS (T
Externí odkaz:
https://doaj.org/article/757b1a291fa64d989f66f304930a5ace
Autor:
Keith E. Steele, Tze Heng Tan, René Korn, Karma Dacosta, Charles Brown, Michael Kuziora, Johannes Zimmermann, Brian Laffin, Moritz Widmaier, Lorenz Rognoni, Ruben Cardenes, Katrin Schneider, Anmarie Boutrin, Philip Martin, Jiping Zha, Tobias Wiestler
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 6, Iss 1, Pp 1-14 (2018)
Abstract Background Immuno-oncology and cancer immunotherapies are areas of intense research. The numbers and locations of CD8+ tumor-infiltrating lymphocytes (TILs) are important measures of the immune response to cancer with prognostic, pharmacodyn
Externí odkaz:
https://doaj.org/article/7a113cf31f8c43b6a687bb8add920dde
Autor:
Charles B. Millard, Gary R. Matyas, Jon M. Davis, Keith E. Steele, Patricia M. Legler, Jaimee R. Compton, Laszlo Janosi
Publikováno v:
Toxins, Vol 5, Iss 2, Pp 224-248 (2013)
Vitetta and colleagues identified and characterized a putative vascular leak peptide (VLP) consensus sequence in recombinant ricin toxin A-chain (RTA) that contributed to dose-limiting human toxicity when RTA was administered intravenously in large q
Externí odkaz:
https://doaj.org/article/2d3dda4c6b72499b9dcef342ec190dd0
Autor:
Simon Lanzmich, Marietta Scott, Armin Meier, Aleksandra Zuraw, Abraham Silva, Marlon Rebelatto, Alexander Haragan, Tobias Wiestler, Craig Barker, Günter Schmidt, Katharina Nekolla, Keith E Steele, Ansh Kapil, Nicolas Brieu
Publikováno v:
IEEE Transactions on Medical Imaging. 40:2513-2523
We report the ability of two deep learning-based decision systems to stratify non-small cell lung cancer (NSCLC) patients treated with checkpoint inhibitor therapy into two distinct survival groups. Both systems analyze functional and morphological p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc12251bd35dbc62bcc040e927044f83
https://doi.org/10.1109/tmi.2021.3081396
https://doi.org/10.1109/tmi.2021.3081396
Autor:
Claire, Germain, Priyanka, Devi-Marulkar, Samantha, Knockaert, Jérôme, Biton, Hélène, Kaplon, Laïla, Letaïef, Jérémy, Goc, Agathe, Seguin-Givelet, Dominique, Gossot, Nicolas, Girard, Pierre, Validire, Marine, Lefèvre, Diane, Damotte, Marco, Alifano, François M, Lemoine, Keith E, Steele, Jean-Luc, Teillaud, Scott A, Hammond, Marie-Caroline, Dieu-Nosjean
Publikováno v:
Frontiers in Immunology
The presence of tertiary lymphoid structures (TLS) in the tumor microenvironment is associated with better clinical outcome in many cancers. In non-small cell lung cancer (NSCLC), we have previously showed that a high density of B cells within TLS (T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::07f84fce76370946f4c7ef005b49c880
https://pubmed.ncbi.nlm.nih.gov/33763071
https://pubmed.ncbi.nlm.nih.gov/33763071
Autor:
Ignacio I Wistuba, Michael T Tetzlaff, Carlo B Bifulco, Katharina von Loga, Sacha Gnjatic, Scott J Rodig, Keith E Steele, Marlon C Rebelatto, Ana Lako, Guray Akturk, Michael Angelo, Shirley Greenbaum, Noah F Greenwald, Cyrus V Hedvat, Travis J Hollmann, Jonathan Juco, Jaime Rodriguez-Canales, Kurt A Schalper, Edward C Stack, Cláudia S Ferreira, Konstanty Korski, Emanuel Schenck, Michael J Surace
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doajarticles::7bf3be5d1fede6e6cdd97ba97f9f858b
https://jitc.bmj.com/content/8/1/e000325corr1.full
https://jitc.bmj.com/content/8/1/e000325corr1.full
Publikováno v:
Methods in enzymology. 635
Multiplex immunofluorescence (MIF) staining of tumor sections combined with computational pathology quantifies phenotypic variants of tumor and immune cells and assesses their spatial relationships. Here, we discuss a MIF panel composed of cytokerati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::13221bd4f2b33d9c7f4553bdb6fde676
https://pubmed.ncbi.nlm.nih.gov/32122552
https://pubmed.ncbi.nlm.nih.gov/32122552
Autor:
David L. Rimm, Janis M. Taube, Cyrus Hedvat, Sacha Gnjatic, Carlo Bifulco, Emanuel Schenck, Katharina von Loga, Marlon Rebelatto, Keith E Steele, Kurt A. Schalper, Michael Surace, Ana Lako, Konstanty Korski, Michael Angelo, Elizabeth L. Engle, Guray Akturk, Ignacio I. Wistuba, Noah F. Greenwald, Cláudia Ferreira, Edward C. Stack, Jonathan Juco, Travis J. Hollmann, Jaime Rodriguez-Canales, Scott J. Rodig, Michael T. Tetzlaff, Shirley Greenbaum, Edwin R. Parra
Publikováno v:
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
ObjectivesThe interaction between the immune system and tumor cells is an important feature for the prognosis and treatment of cancer. Multiplex immunohistochemistry (mIHC) and multiplex immunofluorescence (mIF) analyses are emerging technologies tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d8a5b3b3656585681adf629ee85fccc
https://pubmed.ncbi.nlm.nih.gov/32499296
https://pubmed.ncbi.nlm.nih.gov/32499296
Multiplex immunofluorescence (MIF) staining of tumor sections combined with computational pathology quantifies phenotypic variants of tumor and immune cells and assesses their spatial relationships. Here, we discuss a MIF panel composed of cytokerati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16a8f72bda2f5db4a6b317f9ca73c3d9
https://doi.org/10.1016/bs.mie.2019.07.039
https://doi.org/10.1016/bs.mie.2019.07.039
Autor:
Jaime Rodriguez-Canales, Claudia Windmueller, Farzad Sekhavati, Karma Dacosta, Keith E Steele, Ruben Cardenes, Charles Brown
Publikováno v:
J Histochem Cytochem
There is an important need in immuno-oncology to develop reliable immunohistochemistry (IHC) to assess the expression of CTLA-4+ tumor-infiltrating lymphocytes in human cancers and quantify them with image analysis (IA). We used commercial polyclonal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc6b3b612f5fafa6080a7d85e46008e1
https://pubmed.ncbi.nlm.nih.gov/31609157
https://pubmed.ncbi.nlm.nih.gov/31609157