Zobrazeno 1 - 10
of 219
pro vyhledávání: '"Keith E. Mostov"'
Autor:
Ying Yang, Pekka Paivinen, Chang Xie, Alexis Leigh Krup, Tomi P. Makela, Keith E. Mostov, Jeremy F. Reiter
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
The mechanisms underlying tubular organ elongation remain poorly understood. Here, the authors show that primary cilia interpret Hedgehog signals to pattern the developing gut and that smooth muscle in the gut wall generates mechanical forces that di
Externí odkaz:
https://doaj.org/article/83752cdb44f4477cb1159ac65b303db8
Autor:
Pavel I. Nedvetsky, Ivo Cornelissen, Thomas Mathivet, Claire Bouleti, Phalla Ou, Pieter Baatsen, Xiaocheng Zhao, Frans Schuit, Fabio Stanchi, Keith E. Mostov, Holger Gerhardt
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 11419 (2022)
During vascular development, endothelial cAMP-dependent protein kinase A (PKA) regulates angiogenesis by controlling the number of tip cells, and PKA inhibition leads to excessive angiogenesis. Whether this role of endothelial PKA is restricted to em
Externí odkaz:
https://doaj.org/article/8396e94963b1405188e4f60aa17ae4be
Autor:
Álvaro Román-Fernández, Julie Roignot, Emma Sandilands, Marisa Nacke, Mohammed A. Mansour, Lynn McGarry, Emma Shanks, Keith E. Mostov, David M. Bryant
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
During de novo establishment of apical-basal polarity, a basolateral membrane must be converted into an apical delivery zone. Here, the authors use MDCK 3D cysts to uncover that the phospholipid PI(3,4)P2 is an apical membrane determinant.
Externí odkaz:
https://doaj.org/article/e0c77c25596d44b6bed03dae472c2b55
Autor:
Tianfang Wang, Sang-Ho Kwon, Xiao Peng, Severine Urdy, Zefu Lu, Robert J. Schmitz, Stephen Dalton, Keith E. Mostov, Shaying Zhao
Publikováno v:
iScience, Vol 23, Iss 10, Pp 101629- (2020)
Summary: Madin-Darby canine kidney II (MDCKII) cells are widely used to study epithelial morphogenesis. To better understand this process, we performed time course RNA-seq analysis of MDCKII 3D cystogenesis, along with polarized 2D cells for comparis
Externí odkaz:
https://doaj.org/article/e75671131a094928b5bd9f0c68d28aa5
Autor:
Jan Borén, Levent M. Akyürek, Per Fogelstrand, Matias Ekstrand, Joakim Karlsson, Max Levin, Malin Levin, Keith E. Mostov, Lars Ny, Martin O. Bergo, Jonas Nilsson, Sara Bjursten, Zhiyuan Zhao, Kristell Le Gal, Andrew J. Ewald, Ankur Pandita
Publikováno v:
The American journal of pathology, vol 191, iss 11
Am J Pathol
Am J Pathol
Angiogenesis supplies oxygen and nutrients to growing tumors. Inhibiting angiogenesis may stop tumor growth, but vascular endothelial growth factor inhibitors have limited effect in most tumors. This limited effect may be explained by an additional,
Autor:
Wallace F. Marshall, Leonardo Morsut, Wendell A. Lim, Keith E. Mostov, Paul Brakeman, Wei Yu, Ross J. Metzger
Publikováno v:
Cell systems, vol 9, iss 3
Cell Syst
Cell Syst
Many metazoan organs are comprised of branching trees of epithelial tubes; how patterning occurs in these trees is a fundamental problem of development. Commonly, branch tips fill the volume of the organ approximately uniformly, e.g. in mammalian lun
Autor:
Keith E. Mostov, Álvaro Román-Fernández, Mohammed A. Mansour, Lynn McGarry, David M. Bryant, Julie Roignot, Emma Shanks, Marisa Nacke, Emma Sandilands
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Nature communications, vol 9, iss 1
Nature Communications
Roman-Fernandez, Alvaro; Roignot, Julie; Sandilands, Emma; Nacke, Marisa; Mansour, Mohammed A; McGarry, Lynn; et al.(2018). The phospholipid PI(3,4)P-2 is an apical identity determinant. NATURE COMMUNICATIONS, 9(1), 5041. doi: 10.1038/s41467-018-07464-8. UCSF: Retrieved from: http://www.escholarship.org/uc/item/8vf614x7
Nature communications, vol 9, iss 1
Nature Communications
Roman-Fernandez, Alvaro; Roignot, Julie; Sandilands, Emma; Nacke, Marisa; Mansour, Mohammed A; McGarry, Lynn; et al.(2018). The phospholipid PI(3,4)P-2 is an apical identity determinant. NATURE COMMUNICATIONS, 9(1), 5041. doi: 10.1038/s41467-018-07464-8. UCSF: Retrieved from: http://www.escholarship.org/uc/item/8vf614x7
Apical-basal polarization is essential for epithelial tissue formation, segregating cortical domains to perform distinct physiological functions. Cortical lipid asymmetry has emerged as a determinant of cell polarization. We report a network of phosp
Publikováno v:
eLife, Vol 2 (2013)
Apical secretion from epithelial tubes of the Drosophila embryo is mediated by apical F-actin cables generated by the formin-family protein Diaphanous (Dia). Apical localization and activity of Dia are at the core of restricting F-actin formation to
Externí odkaz:
https://doaj.org/article/c66273c97d0a4fdbab3fdc17b75b88e6
Autor:
Jeremy F. Reiter, Chang Xie, Keith E. Mostov, Alexis Leigh Krup, Ying Yang, Pekka Paivinen, Tomi P. Mäkelä
SummaryDuring development, many tubular organs undergo extensive longitudinal growth to reach their defined length, essential for their function, but how they lengthen is poorly understood. Here, we found that primary cilia are critical for the elong
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51d49a7a5b472aec49964a651b9ee04b
https://doi.org/10.1101/2020.08.31.276295
https://doi.org/10.1101/2020.08.31.276295
Autor:
Kyra Campbell, Ruby Yun-Ju Huang, Binhua P. Zhou, Yoshiko Takahashi, Yibin Kang, Cédric Blanpain, Antonio García de Herreros, Ben Z. Stanger, Amparo Cano, Gerhard Christofori, Jordi Casanova, Jean Paul Thiery, Jing Yang, Chaya Kalcheim, Geert Berx, Raghu Kalluri, Sendurai A. Mani, Marc P. Stemmler, Yeesim Khew-Goodall, Marianne E. Bronner, Thomas Brabletz, Heide L. Ford, Masatoshi Takeichi, Jonas Fuxe, Rik Derynck, Anna-Katerina Hadjantonakis, Shoukat Dedhar, Parker B. Antin, M. Angela Nieto, Donald F. Newgreen, Herbert Levine, Raymond B. Runyan, Guojun Sheng, Robert A. Weinberg, Gregory J. Goodall, Keith E. Mostov, Erik W. Thompson, Roberto Mayor, Eric Theveneau, Pierre Savagner, Alain Puisieux, Jinsong Liu, Joan Massagué, Elizabeth D. Williams, Gregory D. Longmore, Jianhua Xing, David R. McClay
Publikováno v:
Nature reviews. Molecular cell biology, 21 (6
Nature Reviews. Molecular Cell Biology
Biblos-e Archivo: Repositorio Institucional de la UAM
Universidad Autónoma de Madrid
Digital.CSIC. Repositorio Institucional del CSIC
instname
Biblos-e Archivo. Repositorio Institucional de la UAM
NATURE REVIEWS MOLECULAR CELL BIOLOGY
Nature Reviews. Molecular Cell Biology
Biblos-e Archivo: Repositorio Institucional de la UAM
Universidad Autónoma de Madrid
Digital.CSIC. Repositorio Institucional del CSIC
instname
Biblos-e Archivo. Repositorio Institucional de la UAM
NATURE REVIEWS MOLECULAR CELL BIOLOGY
On behalf of the EMT International Association (TEMTIA).
Epithelial–mesenchymal transition (EMT) encompasses dynamic changes in cellular organization from epithelial to mesenchymal phenotypes, which leads to functional changes in cell migratio
Epithelial–mesenchymal transition (EMT) encompasses dynamic changes in cellular organization from epithelial to mesenchymal phenotypes, which leads to functional changes in cell migratio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d459f964c39138d9c74c1f6c5322d660
https://resolver.caltech.edu/CaltechAUTHORS:20200420-125839736
https://resolver.caltech.edu/CaltechAUTHORS:20200420-125839736