Metabolic Activation of CsgD in the Regulation of Salmonella Biofilms

Autor: Akosiererem S. Sokaribo, Elizabeth G. Hansen, Madeline McCarthy, Taseen S. Desin, Landon L. Waldner, Keith D. MacKenzie, George Mutwiri, Nancy J. Herman, Dakoda J. Herman, Yejun Wang, Aaron P. White

Publikováno v: Microorganisms, Vol 8, Iss 7, p 964 (2020)

Among human food-borne pathogens, gastroenteritis-causing Salmonella strains have the most real-world impact. Like all pathogens, their success relies on efficient transmission. Biofilm formation, a specialized physiology characterized by multicellul

Externí odkaz: https://doaj.org/article/d7d34cf0019b41d0b5ee0a4f18231ec6

Examining the Link between Biofilm Formation and the Ability of Pathogenic Salmonella Strains to Colonize Multiple Host Species

Autor: Keith D. MacKenzie, Melissa B. Palmer, Wolfgang L. Köster, Aaron P. White

Publikováno v: Frontiers in Veterinary Science, Vol 4 (2017)

Salmonella are important pathogens worldwide and a predominant number of human infections are zoonotic in nature. The ability of strains to form biofilms, which is a multicellular behavior characterized by the aggregation of cells, is predicted to be

Externí odkaz: https://doaj.org/article/c74e2f564b7e4200ae138e394c876959

In vivo synthesis of bacterial amyloid curli contributes to joint inflammation during S. Typhimurium infection.

Autor: Amanda L Miller, J Alex Pasternak, Nicole J Medeiros, Lauren K Nicastro, Sarah A Tursi, Elizabeth G Hansen, Ryan Krochak, Akosiererem S Sokaribo, Keith D MacKenzie, Melissa B Palmer, Dakoda J Herman, Nikole L Watson, Yi Zhang, Heather L Wilson, R Paul Wilson, Aaron P White, Çagla Tükel

Publikováno v: PLoS Pathogens, Vol 16, Iss 7, p e1008591 (2020)

Reactive arthritis, an autoimmune disorder, occurs following gastrointestinal infection with invasive enteric pathogens, such as Salmonella enterica. Curli, an extracellular, bacterial amyloid with cross beta-sheet structure can trigger inflammatory

Externí odkaz: https://doaj.org/article/1badb525e2964d4b81ab1e7a66ba92da

A Complete Whole-Genome Sequence of Ignavigranum ruoffiae Strain CPL 242382-20, an Opportunistic Human Pathogen Recovered from a Breast Cyst

Autor: Danae M. Suchan, Kara D. Loos, Keith D. MacKenzie, Sean D. Workman, Lori Johnson, Andrew D. S. Cameron, David C. Alexander

Publikováno v: Microbiology Resource Announcements. 12

Ignavigranum ruoffiae is a rare human pathogen. Strain CPL 242382-20 was isolated in Manitoba, Canada, from a breast cyst. Whole-genome sequencing was performed with the Oxford Nanopore Technologies MinION and Illumina MiSeq platforms. The circular c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4a9d25af34a46d48f552b61d6a5b2f7
https://doi.org/10.1128/mra.00521-22

Redefining the H-NS protein family: a diversity of specialized core and accessory forms exhibit hierarchical transcriptional network integration

Autor: Daniel M. Stoebel, Stefani C. Kary, Andrew D. S. Cameron, Tzu-Chiao Chao, Ebtihal Y Alshabib, Stephen F. Fitzgerald, Keith D. MacKenzie

Publikováno v: Fitzgerald, S, Kary, S C, Alshbib, E Y, Mackenzie, K D, Stoebel, D M, Chao, T-C & Cameron, A D S 2020, ' Redefining the H-NS protein family: a diversity of specialized core and accessory forms exhibit hierarchical transcriptional network integration ', Nucleic Acids Research . https://doi.org/10.1093/nar/gkaa709
Nucleic Acids Research

H-NS is a nucleoid structuring protein and global repressor of virulence and horizontally-acquired genes in bacteria. H-NS can interact with itself or with homologous proteins, but protein family diversity and regulatory network overlap remain poorly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc47b6df31342cf811a513685a654327
https://doi.org/10.1093/nar/gkaa709