Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Keith D Kauffman"'
Autor:
Christine E Nelson, Taylor W Foreman, Eduardo R Fukutani, Keith D Kauffman, Shunsuke Sakai, Joel D Fleegle, Felipe Gomez, NIAID/DIR Tuberculosis Imaging Program, Sydnee T Gould, Cyril Le Nouën, Xueqiao Liu, Tracey L Burdette, Nicole L Garza, Bernard A P Lafont, Kelsie Brooks, Cecilia S Lindestam Arlehamn, Daniela Weiskopf, Alessandro Sette, Heather D Hickman, Ursula J Buchholz, Reed F Johnson, Jason M Brenchley, James P Oberman, Artur T L Quieroz, Bruno B Andrade, Laura E Via, Daniel L Barber
Publikováno v:
PLoS Pathogens, Vol 20, Iss 7, p e1012339 (2024)
The regulation of inflammatory responses and pulmonary disease during SARS-CoV-2 infection is incompletely understood. Here we examine the roles of the prototypic pro- and anti-inflammatory cytokines IFNγ and IL-10 using the rhesus macaque model of
Externí odkaz:
https://doaj.org/article/4f2fca22c4d14a298492237eba187e8e
Autor:
Shunsuke Sakai, Keith D Kauffman, Michelle A Sallin, Arlene H Sharpe, Howard A Young, Vitaly V Ganusov, Daniel L Barber
Publikováno v:
PLoS Pathogens, Vol 12, Iss 5, p e1005667 (2016)
IFN-γ-producing CD4 T cells are required for protection against Mycobacterium tuberculosis (Mtb) infection, but the extent to which IFN-γ contributes to overall CD4 T cell-mediated protection remains unclear. Furthermore, it is not known if increas
Externí odkaz:
https://doaj.org/article/7f77a02e79c44c3fbea7435cc5c4fc21
Autor:
Edward Sionov, Katrin D Mayer-Barber, Yun C Chang, Keith D Kauffman, Michael A Eckhaus, Andres M Salazar, Daniel L Barber, Kyung J Kwon-Chung
Publikováno v:
PLoS Pathogens, Vol 11, Iss 8, p e1005040 (2015)
Cryptococcus neoformans is the most common cause of fungal meningoencephalitis in AIDS patients. Depletion of CD4 cells, such as occurs during advanced AIDS, is known to be a critical risk factor for developing cryptococcosis. However, the role of HI
Externí odkaz:
https://doaj.org/article/908caa3c0c7e43f18586b6670336c2eb
Autor:
Stella G. Hoft, Keith D. Kauffman, Shunsuke Sakai, Cecilia S. Lindestam Arlehamn, Alessandro Sette, Daniel F. Hoft, Richard Herbert, Daniel L. Barber
Publikováno v:
mBio, Vol 14, Iss 2 (2023)
ABSTRACT Alternative delivery routes of the current Mycobacterium tuberculosis (Mtb) vaccine, intradermally (ID) delivered BCG, may provide better protection against tuberculosis, and be more easily administered. Here, we use rhesus macaques to compa
Externí odkaz:
https://doaj.org/article/0ede394fe9264bd2be150bdaf50800d8
Autor:
Andrea C. Bohrer, Ehydel Castro, Claire E. Tocheny, Maike Assmann, Benjamin Schwarz, Eric Bohrnsen, Michelle A. Makiya, Fanny Legrand, Kerry L. Hilligan, Paul J. Baker, Flor Torres-Juarez, Zhidong Hu, Hui Ma, Lin Wang, Liangfei Niu, Zilu Wen, Sang H. Lee, Olena Kamenyeva, Keith D. Kauffman, Michele Donato, Alan Sher, Daniel L. Barber, Laura E. Via, Thomas J. Scriba, Purvesh Khatri, Yanzheng Song, Ka-Wing Wong, Catharine M. Bosio, Amy D. Klion, Katrin D. Mayer-Barber
Publikováno v:
Cell Reports, Vol 40, Iss 4, Pp 111144- (2022)
Summary: Influx of eosinophils into the lungs is typically associated with type II responses during allergy and fungal and parasitic infections. However, we previously reported that eosinophils accumulate in lung lesions during type I inflammatory re
Externí odkaz:
https://doaj.org/article/4cc9d670630f4c0ab39dbfc2f415fe75
Autor:
Arundhathi Venkatasubramaniam, Grant Liao, Eunice Cho, Rajan P. Adhikari, Tom Kort, Frederick W. Holtsberg, Karen E. Elsass, Dean J. Kobs, Thomas L. Rudge, Keith D. Kauffman, Nickiana E. Lora, Daniel L. Barber, M. Javad Aman, Hatice Karauzum
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Staphylococcus aureus is a leading cause of significant morbidity and mortality and an enormous economic burden to public health worldwide. Infections caused by methicillin-resistant S. aureus (MRSA) pose a major threat as MRSA strains are becoming i
Externí odkaz:
https://doaj.org/article/c83a2f964899456781ac389d4bee43fb
Autor:
Taylor W. Foreman, Christine E. Nelson, Michelle A. Sallin, Keith D. Kauffman, Shunsuke Sakai, Francisco Otaizo-Carrasquero, Timothy G. Myers, Daniel L. Barber
Publikováno v:
Journal of Experimental Medicine. 220
Control of Mycobacterium tuberculosis (Mtb) infection requires generation of T cells that migrate to granulomas, complex immune structures surrounding sites of bacterial replication. Here we compared the gene expression profiles of T cells in pulmona
Autor:
Eduardo P. Amaral, Taylor W. Foreman, Sivaranjani Namasivayam, Kerry L. Hilligan, Keith D. Kauffman, Caio Cesar Barbosa Bomfim, Diego L. Costa, Beatriz Barreto-Duarte, Clarissa Gurgel-Rocha, Monique Freire Santana, Marcelo Cordeiro-Santos, Elsa Du Bruyn, Catherine Riou, Kate Aberman, Robert John Wilkinson, Daniel L. Barber, Katrin D. Mayer-Barber, Bruno B. Andrade, Alan Sher
Cellular necrosis during Mycobacterium tuberculosis (Mtb) infection promotes both immunopathology and bacterial dissemination. Glutathione peroxidase-4 (Gpx4) is an enzyme that plays a critical role in preventing iron-dependent lipid peroxidation–m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::305757cd850db2f6e16c842d68c85e66
http://hdl.handle.net/10044/1/100503
http://hdl.handle.net/10044/1/100503
Autor:
Keith D. Kauffman, Clifton E. Barry, Shunsuke Sakai, Sangmi Oh, Daniel L. Barber, Christine E. Nelson
Publikováno v:
Mucosal Immunology. 14:199-208
Mucosal-associated invariant T (MAIT) cells are potential targets of vaccination and host-directed therapeutics for tuberculosis, but the role of MAIT cells during Mycobacterium tuberculosis (Mtb) infection in vivo is not well understood. Here we fin
Autor:
Yanzheng Song, Luman Wang, David M. Lowe, Linda Petrone, Clifton E. Barry, Amy D. Klion, Laura E. Via, Franca Del Nonno, Christine E. Nelson, Shunsuke Sakai, Bruno B. Andrade, Honghui Ma, Keith D. Kauffman, Ka-Wing Wong, Daniel L. Barber, Delia Goletti, Andrea C. Bohrer, Catherine Riou, Zhibin Hu, Robert J. Wilkinson, Maike Assmann, Ian N. Moore, du Bruyn E, Paul J. Baker, Mark R. Cronan, Ehydel Castro, Artur T. L. Queiroz, Adrian R. Martineau, Wen Zilu, Katrin D. Mayer-Barber, Claire E. Tocheny
Host resistance to Mycobacterium tuberculosis infection requires the activities of multiple leukocyte subsets, yet the roles of the different innate effector cells during tuberculosis are incompletely understood. Here we uncover an unexpected associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40c4a7c486e9463da59fe3f673b44d59
https://doi.org/10.1101/2021.05.29.446277
https://doi.org/10.1101/2021.05.29.446277