Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Keith D Harshman"'
Autor:
Benjamin R. Bowen, Keith D Harshman, Wei Ding, C. Capener, K Bulka, Mark H. Skolnick, Victor Abkevich, Jathine Wong, Bryan Wardell, B. Campbell, E. N. Kort, Steven C. Hunt, M. McDermott, Hui-Chun Wang, Alexander Gutin, Dennis G. Ballinger, Mark E. Samuels, T. Thorne, Paul N. Hopkins
Publikováno v:
The American Journal of Human Genetics. 66:1845-1856
Coronary heart disease (CHD) accounts for half of the 1 million deaths annually ascribed to cardiovascular disease and for almost all of the 1.5 million acute myocardial infarctions. Within families affected by early and apparently heritable CHD, dys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7b445f3f00551f89cb62ac16c66bc42
https://doi.org/10.1086/302945
https://doi.org/10.1086/302945
Autor:
Sean V. Tavtigian, Jane Weaver-Feldhaus, Keith D Harshman, Bruce E. Johnson, Alexander Kamb, Qingyun Liu, Mark H. Skolnick, Nelleke A. Gruis, Elisabeth Stockert, Rufus S. Day
Publikováno v:
Science. 264:436-440
A putative tumor suppressor locus on the short arm of human chromosome 9 has been localized to a region of less than 40 kilobases by means of homozygous deletions in melanoma cell lines. This region contained a gene, Multiple Tumor Suppressor 1 (MTS1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e58bcad11c36232f8890012d1b22bba
https://doi.org/10.1126/science.8153634
https://doi.org/10.1126/science.8153634
Autor:
Mei Lai, Thomas Haltier, Franklin H. Norris, Daniel Shaffer, Charles E. Hussey, Wei Ding, Keith D Harshman, Katherine K. Richardson, Thanh Tran, Robert Phelps, Russell Bell, Pamela K. Bristow, Priya Dayananth, Steven Bayer, Yoshio MlKl, Harold Katcher, Ken Eddington, Jeff Swenson, Mark H. Skolnick, Paul Robert Rosteck, Judith Rosenthal, Cheryl Frye, Donna M Shattuck-Eidens, Alexander Kamb, Zahra Gholami, Brad Dehoff, Steven Stone
Publikováno v:
Human molecular genetics. 4(8)
A critical step in positional cloning is the identification of candidate genes from a large, genetically defined region. Candidate gene isolation by hybrid selection, genomic sequencing, and direct cDNA library screening identified 45 candidate gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bfd9a8982396fa61ae3d2ed7bd6b47d
https://pubmed.ncbi.nlm.nih.gov/7581362
https://pubmed.ncbi.nlm.nih.gov/7581362
Autor:
Charles Cochran, Keith D Harshman, Wei Ding, Yoshio Miki, L. Michelle Bennett, Peter Söderkvist, Alexander Kamb, Sean V. Tavtigian, Zahra Gholami, Qingyun Liu, Suresh C. Jhanwar, Dennis G. Ballinger, Jeff Swensen, Donna M Shattuck-Eidens, Roger W. Wiseman, Astrid Haugen-Strano, Cheryl Frye, P. Andrew Futreal, Mark H. Skolnick, J. Cari Barrett, Jane Weaver-Feldhaus, Lori A. Terry, Jeffrey R. Marks, J. Dirk Iglehart, Andrew Berchuck, Melody McClure, Ken Eddington
Publikováno v:
Science (New York, N.Y.). 266(5182)
Loss of heterozygosity data from familial tumors suggest that BRCA1, a gene that confers susceptibility to ovarian and early-onset breast cancer, encodes a tumor suppressor. The BRCA1 region is also subject to allelic loss in sporadic breast and ovar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52820dc29c5f94f2cbe151f0ced87113
https://pubmed.ncbi.nlm.nih.gov/7939630
https://pubmed.ncbi.nlm.nih.gov/7939630
Autor:
Charles Cochran, Sean V. Tavtigian, Jeffrey R. Marks, Maurine R. Hobbs, Jeff Swensen, Keith D Harshman, Robert Phelps, Russell Bell, Qingyun Liu, Judith Rosenthal, Donna M Shattuck-Eidens, P. Andrew Futreal, Alexander Kamb, Charles E. Hussey, Yoshio Miki, J. Carl Barrett, Roger W. Wiseman, Thanh Tran, L. Michelle Bennett
Publikováno v:
Genomics. 23(1)
The VH1-related human protein (VHR) gene was localized to human chromosome 17q21 in a region thought to contain the BRCA1 locus, a locus that confers susceptibility to breast and ovarian cancer. VHR encodes a phosphatase with dual specificity for tyr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eae39461fc939b96022348b8e695885f
https://pubmed.ncbi.nlm.nih.gov/7829067
https://pubmed.ncbi.nlm.nih.gov/7829067
The calphotin protein, encoded by the calphotin (cap) gene, is expressed in the soma and axons of all Drosophila photoreceptor cells. It is expressed early in photo-receptor cell development, at the time when cell-type decisions are being made. Expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a1a8949b0df81c1099114ff60a7bcf5
https://europepmc.org/articles/PMC45909/
https://europepmc.org/articles/PMC45909/
Autor:
Carlos Cordon-Cardo, Alexander Kamb, Qingyun Liu, Mark H. Skolnick, Keith D Harshman, Sean V. Tavtigian
Publikováno v:
Science. 265:416-417
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae4555759a55d748fa6777473d454c4e
https://doi.org/10.1126/science.265.5170.416
https://doi.org/10.1126/science.265.5170.416