Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Keith Crowshaw"'
Publikováno v:
Circulation Research. 32:712-717
Inhibition of prostaglandin synthesis in chloralose-anesthetized dogs reduced renal blood flow, and this reduction closely correlated (r=0.92, P 2 . We used solvent extraction and thin-layer chromatography coupled with parallel bioassay to identify a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1edcd082341c49d605708550d1b7d90c
https://doi.org/10.1161/01.res.32.6.712
https://doi.org/10.1161/01.res.32.6.712
Autor:
J. C. McGiff, Norberto A. Terragno, Kevin K. F. Ng, James C. Strand, Andrew J. Lonigro, Mary Anne Williamson, James B. Lee, Keith Crowshaw
Publikováno v:
Circulation Research. 27:765-782
Renal prostaglandins (PC s ) might mediate an antihypertensive function of the kidney. The blood-superfused organ technique possesses the sensitivity (threshold < 0.4 ng/ml blood) and specificity required for identification of PGs in blood. Induction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1594dc0510a216875864328fafd7a76
https://doi.org/10.1161/01.res.27.5.765
https://doi.org/10.1161/01.res.27.5.765
Publikováno v:
Nature. 227:1255-1257
WE describe here the release from the kidney by angiotensin II and noradrenaline of substances which have the properties of prostaglandins. This observation may help to account for the antihypertensive function of the kidney first suggested by Fascio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c474414e36ae29dbaaab701987a5ce1a
https://doi.org/10.1038/2271255b0
https://doi.org/10.1038/2271255b0
Autor:
Michael P.L. Caton, Keith Crowshaw
(±)-11-Deoxyprostaglandins of the E 1 series are synthesised by elaboration of the aldehyde (vii) which is prepared from the enone (iv) via thenitrile (vi) or nitromethyl compound (xii). The stereochemistry of the intermediates is discussed and evid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3b0e6a491defb8bf6fc995e0bd8396d
https://doi.org/10.1016/b978-0-12-405850-7.50011-4
https://doi.org/10.1016/b978-0-12-405850-7.50011-4
Autor:
Keith Crowshaw
Publikováno v:
Nature: New biology. 231(25)
THIS report describes the biosynthesis of the naturally occurring renal prostaglandins E2 (PGE2) and F2α (PGF2α)1,2 by homogenates and slices of rabbit renal medulla, from endogenous precursors. I have confirmed that rabbit renal cortex contains li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b827ccfddd551fa707788a2ef489c1af
https://pubmed.ncbi.nlm.nih.gov/5284363
https://pubmed.ncbi.nlm.nih.gov/5284363
Publikováno v:
The Journal of pharmacy and pharmacology. 22(4)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::558c4e39179a6ecb423e553b08076184
https://pubmed.ncbi.nlm.nih.gov/4392573
https://pubmed.ncbi.nlm.nih.gov/4392573
Publikováno v:
Clinical science. 42(2)
1. The concentrations of prostaglandin E(PGE)- and prostaglandin F(PGF)-like substances in renal venous blood were determined by parallel bioassay of extracts of renal venous effluent before and during adrenergic stimulation of the kidney and were re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbe6c0fedf4dd70a57d4fea91194c79c
https://pubmed.ncbi.nlm.nih.gov/5058576
https://pubmed.ncbi.nlm.nih.gov/5058576
Autor:
Keith Crowshaw
Publikováno v:
Prostaglandins. 3(5)
1. 1. [1- 14 C]Arachidonic acid is taken up by slices of rabbit renal medulla and cortex and incorporated into tissue phospholipids and neutral lipids. Although arachidonic acid is known to be the precursor of PGE 2 and PGF 2α in rabbit renal medull
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b08e520488261ba4349ecf4f0041d579
https://pubmed.ncbi.nlm.nih.gov/4729593
https://pubmed.ncbi.nlm.nih.gov/4729593
Autor:
J. Z. Szlyk, Keith Crowshaw
Three prostaglandins (PGE(2), PGF(2alpha) and PGA(2)) are present in rabbit kidney medulla. An acidic lipid extract (0.165g) obtained from 2kg of frozen rabbit kidney cortex was separated by silicic acid chromatography to yield eluates containing fat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afd9e50b7fc499e9d9e846309c92e79f
https://europepmc.org/articles/PMC1185380/
https://europepmc.org/articles/PMC1185380/
Autor:
JamesB Lee, Keith Crowshaw
Publikováno v:
The Lancet. 291:247
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b192122f0aac482d7727b50d83c7e4e6
https://doi.org/10.1016/s0140-6736(68)90877-5
https://doi.org/10.1016/s0140-6736(68)90877-5