Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Keith Charrier"'
Autor:
John R. Doedens, Beverly J Castner, Guixian Jin, Susan W. Sunnarborg, Roy A. Black, R. Cowling, Jennifer L. Slack, Richard S. Johnson, Keith Charrier, Ray Paxton, Duke Virca, David C. Lee, Lin Guo, Alison Wallace, Jacques J. Peschon, Rajeev M Mahimkar, June R. Eisenman
Publikováno v:
Biochemical Society Symposia. 70:39-52
Tumour necrosis factor α (TNFα)-converting enzyme (TACE/ADAM-17, where ADAM stands for a disintegrin and metalloproteinase) releases from the cell surface the extracellular domains of TNF and several other proteins. Previous studies have found that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9727d6426c1d576731fc2cee98f33d8
https://doi.org/10.1042/bss0700039
https://doi.org/10.1042/bss0700039
Autor:
J.Greg Murison, Annjanette S. Warren, Timothy A. Bird, Jonathan M.J. Derry, Keith Charrier, Moira Glaccum, Pamela M. Holland, Suzanne Kanaly, Jacques J. Peschon, Cynthia R. Willis, G. Duke Virca
Publikováno v:
Current Biology. 12(16):1424-1428
The epidermis is a stratified, continually renewing epithelium dependent on a balance among cell proliferation, differentiation, and death for homeostasis. In normal epidermis, a mitotically active basal layer gives rise to terminally differentiating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec8fa09bb2a7b4f62e905e680dcb88dc
Reversible Defects in Natural Killer and Memory Cd8 T Cell Lineages in Interleukin 15–Deficient Mice
Autor:
Kim L. Stocking, Sandra N. Brown, Sebastian Joyce, Philip J. Morrissey, Monica E. Embers, Naoto Matsuki, Keith Charrier, Eric A. Butz, Lisa M. Sedger, Kenneth Brasel, Moira Glaccum, Jacques J. Peschon, JoAnn C. L. Schuh, Joanne L. Viney, Mary K. Kennedy, Cynthia R. Willis
Publikováno v:
The Journal of Experimental Medicine
C57BL/6 mice genetically deficient in interleukin 15 (IL-15−/− mice) were generated by gene targeting. IL-15−/− mice displayed marked reductions in numbers of thymic and peripheral natural killer (NK) T cells, memory phenotype CD8+ T cells, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94442119fb9637300d5cb06846fc344b
https://doi.org/10.1084/jem.191.5.771
https://doi.org/10.1084/jem.191.5.771
TNF Receptor-Deficient Mice Reveal Divergent Roles for p55 and p75 in Several Models of Inflammation
Autor:
Jacques J. Peschon, Dauphine S. Torrance, Kim L. Stocking, Moira B. Glaccum, Carol Otten, Cynthia R. Willis, Keith Charrier, Philip J. Morrissey, Carol B. Ware, Kendall M. Mohler
Publikováno v:
The Journal of Immunology. 160:943-952
The pleiotropic activities of the potent proinflammatory cytokine TNF are mediated by two structurally related, but functionally distinct, receptors, p55 and p75, that are coexpressed on most cell types. The majority of biologic responses classically
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb6f71c8b610a603a86ab4382bb25a68
https://doi.org/10.4049/jimmunol.160.2.943
https://doi.org/10.4049/jimmunol.160.2.943
Autor:
Douglas E. Williams, Hilary J. McKenna, Chi Chang Lee, Kenneth Brasel, Stewart D. Lyman, Philip J. Morrissey, Arvia E. Morris, Keith Charrier
Publikováno v:
Blood. 88:2004-2012
We have investigated the effects of in vivo treatment with flt3 ligand (FL) on murine hematopoiesis, including mobilization of progenitors into the peripheral blood (PB). Mice were injected once daily with 10 micrograms recombinant human FL for 15 da
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8eae459c7f373dedca80493c6de00ca8
https://doi.org/10.1182/blood.v88.6.2004.bloodjournal8862004
https://doi.org/10.1182/blood.v88.6.2004.bloodjournal8862004
Publikováno v:
The Journal of Experimental Medicine
Purified CD4+ lymph node T cells were sorted into two populations on the basis of their expression of CD45RB (CD45RBhi and CD45RBlo) and injected into congenic severe combined immunodeficient (SCID) mice. After a period of time that was dependent on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8752c600c41adb74f623c459c50c026f
https://doi.org/10.1084/jem.178.1.237
https://doi.org/10.1084/jem.178.1.237
Autor:
Fred H. Rodriguez, Ping Zhang, Suzanne T. Kanaly, Steve Nelson, Peter Oliver, Jason Zhang, Keith Charrier, Kim L. Stocking, Judd E. Shellito, Weitao Huang, G. J. Bagby, Jay K. Kolls, Paul Schwarzenberger, Jacques J. Peschon, Peng Ye, Jill R. Schurr
Publikováno v:
The Journal of Experimental Medicine
Bacterial pneumonia is an increasing complication of HIV infection and inversely correlates with the CD4+ lymphocyte count. Interleukin (IL)-17 is a cytokine produced principally by CD4+ T cells, which induces granulopoiesis via granulocyte colony-st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1397fc6d681960db93fb451ffe87ee0d
https://pubmed.ncbi.nlm.nih.gov/11514607
https://pubmed.ncbi.nlm.nih.gov/11514607
Autor:
James D. Watson, Keith Charrier, Douglas E. Williams, Philip J. Morrissey, Hilary J. McKenna, Steve Braddy, Rob Voice, Michael B. Widmer
Publikováno v:
Cellular immunology. 157(1)
The ability of Steel factor (SLF) to stimulate the growth of immature thymocytes alone and in combination with IL-7 was assessed. In suspension cultures of CD4 - /CD8 - thymocytes. SLF itself did not induce significant proliferation, but in combinati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::add29758bf8e0983de45d164f587b326
https://pubmed.ncbi.nlm.nih.gov/7518749
https://pubmed.ncbi.nlm.nih.gov/7518749
Autor:
Frederick R. Appelbaum, Jan C. Wulff, George E. Sale, H. Joachim Deeg, Keith Charrier, Rainer Storb, Ted Graham
Publikováno v:
Hematological oncology. 2(2)
Forty cases of naturally occurring canine lymphoma were studied using a panel of murine monoclonal antibodies which identify defined subsets of normal canine lymphocytes. The distribution of phenotypes was similar to that which is seen in man in that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5889a64971e841ed84b1a013fd5fe84
https://pubmed.ncbi.nlm.nih.gov/6540237
https://pubmed.ncbi.nlm.nih.gov/6540237