Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Keith C. Olsen"'
Autor:
Ajit A Kulkarni, Thomas H Thatcher, Hsi-Min Hsiao, Keith C Olsen, Robert Matthew Kottmann, Jason Morrissette, Terry W Wright, Richard P Phipps, Patricia J Sime
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63798 (2013)
Pulmonary Fibrosis (PF) is a devastating progressive disease in which normal lung structure and function is compromised by scarring. Lung fibrosis can be caused by thoracic radiation, injury from chemotherapy and systemic diseases such as rheumatoid
Externí odkaz:
https://doaj.org/article/cc467949afda4006b9c5ce9d4bc6a25b
Autor:
Hsi-Min Hsiao, Ramil E Sapinoro, Thomas H Thatcher, Amanda Croasdell, Elizabeth P Levy, Robert A Fulton, Keith C Olsen, Stephen J Pollock, Charles N Serhan, Richard P Phipps, Patricia J Sime
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58258 (2013)
INTRODUCTION:Cigarette smoke is a profound pro-inflammatory stimulus that contributes to acute lung injuries and to chronic lung disease including COPD (emphysema and chronic bronchitis). Until recently, it was assumed that resolution of inflammation
Externí odkaz:
https://doaj.org/article/9ae1c2a6004846ce93453cc8b2138675
Autor:
Ajit A Kulkarni, Thomas H Thatcher, Keith C Olsen, Sanjay B Maggirwar, Richard P Phipps, Patricia J Sime
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e15909 (2011)
Transforming growth factor beta (TGFβ) induced differentiation of human lung fibroblasts to myofibroblasts is a key event in the pathogenesis of pulmonary fibrosis. Although the typical TGFβ signaling pathway involves the Smad family of transcripti
Externí odkaz:
https://doaj.org/article/714fa35730b0445085726be7c2910c57
Publikováno v:
The American Journal of dermatopathology. 40(2)
Cutaneous complications secondary to transcatheter arterial chemoembolization (TACE) are exceptionally rare and may occur because of nontarget embolization of terminal vessels supplying the skin. We present a patient who developed painful retiform pu
Publikováno v:
Dermatitis : contact, atopic, occupational, drug. 27(4)
Publikováno v:
Infection and Immunity. 80:3912-3920
Pneumocystis is an opportunistic fungal pathogen that causes pneumonia in a variety of clinical settings. An early step in Pneumocystis infection involves the attachment of organisms to alveolar epithelial cells (AECs). AECs produce chemokines in res
Autor:
Ajit A. Kulkarni, Gail V.W. Johnson, Siiri E. Iismaa, Richard P. Phipps, Thomas H. Thatcher, Keith C. Olsen, Ramil Sapinoro, Patricia J. Sime, R.M. Kottmann
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 184:699-707
Rationale: Idiopathic pulmonary fibrosis (IPF) is a deadly progressive disease with few treatment options. Transglutaminase 2 (TG2) is a multifunctional protein, but its function in pulmonary fibrosis is unknown. Objectives: To determine the role of
Autor:
Thomas H. Thatcher, Elizabeth P. Levy, Robert A. Fulton, Charles N. Serhan, Amanda Croasdell, Patricia J. Sime, Stephen J. Pollock, Ramil Sapinoro, Hsi-Min Hsiao, Keith C. Olsen, Richard P. Phipps
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58258 (2013)
PLoS ONE
PLoS ONE
Introduction Cigarette smoke is a profound pro-inflammatory stimulus that contributes to acute lung injuries and to chronic lung disease including COPD (emphysema and chronic bronchitis). Until recently, it was assumed that resolution of inflammation
Autor:
Keith C. Olsen, Ajit A. Kulkarni, RP Phipps, Patricia J. Sime, Katie Smolnycki, R. Matthew Kottmann, Thomas H. Thatcher
Publikováno v:
D39. NOVEL THERAPEUTICS IN PULMONARY FIBROSIS.
Autor:
Patricia J. Sime, Xia Xi, Steven E. Feldon, Shikha Gupta, Stephen J. Pollock, Carolyn J. Baglole, Krystel R. Huxlin, Richard P. Phipps, Ajit A. Kulkarni, Geniece M. Lehmann, Keith C. Olsen, Ann E. Casey
Publikováno v:
The American journal of pathology. 178(4)
Fibrosis can occur in any human tissue when the normal wound healing response is amplified. Such amplification results in fibroblast proliferation, myofibroblast differentiation, and excessive extracellular matrix deposition. Occurrence of these sequ