Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Keith C, Cheng"'
Autor:
Fae N. Kronman, Josephine K. Liwang, Rebecca Betty, Daniel J. Vanselow, Yuan-Ting Wu, Nicholas J. Tustison, Ashwin Bhandiwad, Steffy B. Manjila, Jennifer A. Minteer, Donghui Shin, Choong Heon Lee, Rohan Patil, Jeffrey T. Duda, Jian Xue, Yingxi Lin, Keith C. Cheng, Luis Puelles, James C. Gee, Jiangyang Zhang, Lydia Ng, Yongsoo Kim
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract 3D brain atlases are key resources to understand the brain’s spatial organization and promote interoperability across different studies. However, unlike the adult mouse brain, the lack of developing mouse brain 3D reference atlases hinders
Externí odkaz:
https://doaj.org/article/a5b5166d34af4240a02ab1939e81a491
Monitoring mouse papillomavirus-associated cancer development using longitudinal Pap smear screening
Autor:
Hannah M. Atkins, Aysegul Aksakal Uslu, Jingwei J. Li, Debra A. Shearer, Sarah A. Brendle, Chen Han, Michael Kozak, Paul Lopez, Deesha Nayar, Karla K. Balogh, Catherine Abendroth, Jean Copper, Keith C. Cheng, Neil D. Christensen, Yusheng Zhu, Stefanie Avril, Adam D. Burgener, Thomas T. Murooka, Jiafen Hu
Publikováno v:
mBio, Vol 15, Iss 8 (2024)
ABSTRACT A substantial percentage of the population remains at risk for cervical cancer due to pre-existing human papillomavirus (HPV) infections, despite prophylactic vaccines. Early diagnosis and treatment are crucial for better disease outcomes. T
Externí odkaz:
https://doaj.org/article/6e22c5056c51441a99de50ea519d0897
Autor:
Mee S Ngu, Daniel J Vanselow, Andrew L Sugarman, Rachelle A Saint-Fort, Carolyn R Zaino, Maksim A Yakovlev, Keith C Cheng, Khai C Ang
Publikováno v:
PLoS ONE, Vol 19, Iss 11, p e0313389 (2024)
Micro-CT imaging is a powerful tool for generating high-resolution, isotropic, three-dimensional datasets of whole, centimeter-scale model organisms. At histological resolutions, micro-CT can be used for whole-animal qualitative and quantitative char
Externí odkaz:
https://doaj.org/article/a8bef96cebb14e3d82f5bb295608e1c7
Autor:
Hie Lim Kim, Tanghua Li, Namrata Kalsi, Hung Tran The Nguyen, Timothy A. Shaw, Khai C. Ang, Keith C. Cheng, Aakrosh Ratan, W. Richard Peltier, Dhrubajyoti Samanta, Mahesh Pratapneni, Stephan C. Schuster, Benjamin P. Horton
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-10 (2023)
Population genomic analyses and palaeogeographical modelling combine to help infer the ancient migration of humans into South Asia from Sundaland, driven by rapid sea level rises.
Externí odkaz:
https://doaj.org/article/9119fe3155504c2d93d8ad7ebaf31487
Autor:
Khai C Ang, Victor A Canfield, Tiffany C Foster, Thaddeus D Harbaugh, Kathryn A Early, Rachel L Harter, Katherine P Reid, Shou Ling Leong, Yuka Kawasawa, Dajiang Liu, John W Hawley, Keith C Cheng
Publikováno v:
eLife, Vol 12 (2023)
Our interest in the genetic basis of skin color variation between populations led us to seek a Native American population with genetically African admixture but low frequency of European light skin alleles. Analysis of 458 genomes from individuals re
Externí odkaz:
https://doaj.org/article/a7a57cf3af0744a899d78c2aa70312ca
Autor:
Maksim A. Yakovlev, Daniel J. Vanselow, Mee Siing Ngu, Carolyn R. Zaino, Spencer R. Katz, Yifu Ding, Dula Parkinson, Steve Yuxin Wang, Khai Chung Ang, Patrick La Riviere, Keith C. Cheng
Publikováno v:
Journal of Synchrotron Radiation, Vol 29, Iss 2, Pp 505-514 (2022)
Ideal three-dimensional imaging of complex samples made up of micron-scale structures extending over mm to cm, such as biological tissues, requires both wide field of view and high resolution. For existing optics and detectors used for micro-CT (comp
Externí odkaz:
https://doaj.org/article/e2c1fc4c582741da9130eb44fbce82e3
Autor:
Keith C. Cheng, Rebecca D. Burdine, Mary E. Dickinson, Stephen C. Ekker, Alex Y. Lin, K. C. Kent Lloyd, Cathleen M. Lutz, Calum A. MacRae, John H. Morrison, David H. O'Connor, John H. Postlethwait, Crystal D. Rogers, Susan Sanchez, Julie H. Simpson, William S. Talbot, Douglas C. Wallace, Jill M. Weimer, Hugo J. Bellen
Publikováno v:
Disease Models & Mechanisms, Vol 15, Iss 9 (2022)
Externí odkaz:
https://doaj.org/article/222ed46e51c14f58b45949b868d864dd
Autor:
Spencer R Katz, Maksim A Yakovlev, Daniel J Vanselow, Yifu Ding, Alex Y Lin, Dilworth Y Parkinson, Yuxin Wang, Victor A Canfield, Khai C Ang, Keith C Cheng
Publikováno v:
eLife, Vol 10 (2021)
We previously described X-ray histotomography, a high-resolution, non-destructive form of X-ray microtomography (micro-CT) imaging customized for three-dimensional (3D), digital histology, allowing quantitative, volumetric tissue and organismal pheno
Externí odkaz:
https://doaj.org/article/d40d64fe600d4ee18f7b8f9e921ab330
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Anatomical brain atlases elucidate the anatomical and functional organisation across species but different atlases have conflicting anatomical border and 3D coordinates. The authors integrated two atlases into a unified and highly segmented anatomica
Externí odkaz:
https://doaj.org/article/cc8d3da813b94cfda556d207d89e80d7
Autor:
Yifu Ding, Daniel J Vanselow, Maksim A Yakovlev, Spencer R Katz, Alex Y Lin, Darin P Clark, Phillip Vargas, Xuying Xin, Jean E Copper, Victor A Canfield, Khai C Ang, Yuxin Wang, Xianghui Xiao, Francesco De Carlo, Damian B van Rossum, Patrick La Riviere, Keith C Cheng
Publikováno v:
eLife, Vol 8 (2019)
Organismal phenotypes frequently involve multiple organ systems. Histology is a powerful way to detect cellular and tissue phenotypes, but is largely descriptive and subjective. To determine how synchrotron-based X-ray micro-tomography (micro-CT) can
Externí odkaz:
https://doaj.org/article/a4fe8abecd5345ed8e6fd5e965f76360