Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Keith B Glaser"'
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0114363 (2015)
Constitutive activation of the Janus kinase (JAK)/signal transducer and activator of transcription (STAT) axis is fundamental to the molecular pathogenesis of a host of hematological disorders, including acute leukemias and myeloproliferative neoplas
Externí odkaz:
https://doaj.org/article/0d6bfec9019c409fab628f1f0498b7b3
Autor:
Cherry L. Wainwright, Mauro M. Teixeira, David L. Adelson, Eric J. Buenz, Bruno David, Keith B. Glaser, Yuka Harata-Lee, Melanie-Jayne R. Howes, Angelo A. Izzo, Pasquale Maffia, Alejandro M.S. Mayer, Claire Mazars, David J. Newman, Eimear Nic Lughadha, Adriano M.C. Pimenta, John A.A. Parra, Zhipeng Qu, Hanyuan Shen, Michael Spedding, Jean-Luc Wolfender
Publikováno v:
Pharmacological Research, Vol 180, Iss , Pp 106207- (2022)
Externí odkaz:
https://doaj.org/article/b215426536d141999cb70e91b0a202d1
Autor:
Cherry L. Wainwright, Mauro M. Teixeira, David L. Adelson, Fernão C. Braga, Eric J. Buenz, Priscilla R.V. Campana, Bruno David, Keith B. Glaser, Yuka Harata-Lee, Melanie-Jayne R. Howes, Angelo A. Izzo, Pasquale Maffia, Alejandro M.S. Mayer, Claire Mazars, David J. Newman, Eimear Nic Lughadha, Rodrigo M. Pádua, Adriano M.C. Pimenta, John A.A. Parra, Zhipeng Qu, Hanyuan Shen, Michael Spedding, Jean-Luc Wolfender
Publikováno v:
Pharmacological Research, Vol 177, Iss , Pp 106076- (2022)
Drug discovery from natural sources is going through a renaissance, having spent many decades in the shadow of synthetic molecule drug discovery, despite the fact that natural product-derived compounds occupy a much greater chemical space than those
Externí odkaz:
https://doaj.org/article/7548a631600c45a6b94850aa79d2813e
Autor:
Alejandro MS. Mayer, Marsha Pierce, Maria Reji, Alex C. Wu, Karolina K. Jekielek, Henry Q. Le, Katelyn Howe, Maryam Butt, Sujin Seo, David J. Newman, Keith B. Glaser
Publikováno v:
ASPET 2023 Annual Meeting Abstract - Drug Discovery and Development.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d170d566ef6ffa3e66f796fbb5eb8487
https://doi.org/10.1124/jpet.122.527010
https://doi.org/10.1124/jpet.122.527010
Autor:
Kathleen M. Sakamoto, Keith B. Glaser, Michael C. Heinrich, Diana Griffith, Ajia Presnell, Xiaolin Tan, Elliot M. Landaw, Joan P. Zape, Jenny E. Hernandez-Davies
Supplementary Figure 3 from The Multitargeted Receptor Tyrosine Kinase Inhibitor Linifanib (ABT-869) Induces Apoptosis through an Akt and Glycogen Synthase Kinase 3β–Dependent Pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05a7ee63525783ac9a81acbdd140aaf0
https://doi.org/10.1158/1535-7163.22496235.v1
https://doi.org/10.1158/1535-7163.22496235.v1
Autor:
Kathleen M. Sakamoto, Keith B. Glaser, Michael C. Heinrich, Diana Griffith, Ajia Presnell, Xiaolin Tan, Elliot M. Landaw, Joan P. Zape, Jenny E. Hernandez-Davies
Supplementary Figure 1 from The Multitargeted Receptor Tyrosine Kinase Inhibitor Linifanib (ABT-869) Induces Apoptosis through an Akt and Glycogen Synthase Kinase 3β–Dependent Pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::698a1a335f8501f11935663ce79a6014
https://doi.org/10.1158/1535-7163.22496241.v1
https://doi.org/10.1158/1535-7163.22496241.v1
Autor:
Kathleen M. Sakamoto, Keith B. Glaser, Michael C. Heinrich, Diana Griffith, Ajia Presnell, Xiaolin Tan, Elliot M. Landaw, Joan P. Zape, Jenny E. Hernandez-Davies
Supplementary Figure 2 from The Multitargeted Receptor Tyrosine Kinase Inhibitor Linifanib (ABT-869) Induces Apoptosis through an Akt and Glycogen Synthase Kinase 3β–Dependent Pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08203e2ced20c43292e10459701e6f3b
https://doi.org/10.1158/1535-7163.22496238.v1
https://doi.org/10.1158/1535-7163.22496238.v1
Autor:
Kathleen M. Sakamoto, Keith B. Glaser, Michael C. Heinrich, Diana Griffith, Ajia Presnell, Xiaolin Tan, Elliot M. Landaw, Joan P. Zape, Jenny E. Hernandez-Davies
The FMS-like receptor tyrosine kinase 3 (FLT3) plays an important role in controlling differentiation and proliferation of hematopoietic cells. Activating mutations in FLT3 occur in patients with acute myeloid leukemia (AML; 15%–35%), resulting in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06b3aea7b1fa5cbbd1cbc65071a3339c
https://doi.org/10.1158/1535-7163.c.6535200
https://doi.org/10.1158/1535-7163.c.6535200
Autor:
Alex C. Wu, Karolina K. Jelielek, Henry Q. Le, Maryam Butt, David J. Newman, Keith B. Glaser, Marsha L. Pierce, Alejandro M. Mayer
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11edce84d9e77cd2ce7ff4d2b68179d8
https://doi.org/10.1096/fasebj.2022.36.s1.l7586
https://doi.org/10.1096/fasebj.2022.36.s1.l7586
Autor:
Kenneth Kowalkowski, Keith B. Glaser, Wayne R. Buck, Yi Yang, Rita Ciurlionis, Eric A. G. Blomme, Daniel H. Albert
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 12629, p 12629 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 22; Issue 23; Pages: 12629
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 22; Issue 23; Pages: 12629
Cancer therapies targeting the vascular endothelial growth factor (VEGF) signaling pathway can lead to renal damage by disrupting the glomerular ultrafiltration apparatus. The objective of the current study was to identify sensitive biomarkers for VE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::210f677cdf88bcd6d72e8a4c2ff07611
https://www.mdpi.com/1422-0067/22/23/12629
https://www.mdpi.com/1422-0067/22/23/12629