Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Keith AB"'
Publikováno v:
International Journal of Population Data Science, Vol 9, Iss 5 (2024)
Background & Objectives Trial Emulation methods can be applied to Population-Scale Linked Electronic Health Records (EHR) to generalise the results of Randomised Controlled Trials (RCTs) to a broader patient population. However, the Data Generating M
Externí odkaz:
https://doaj.org/article/7488e110f1ff4997bf9fd5e8cea24f10
Publikováno v:
International Journal of Population Data Science, Vol 9, Iss 5 (2024)
Background and Objectives Healthcare decision-making has previously focused on developing recommendations for single conditions. This research aimed to develop a modeling framework to estimate the effects of multi-indication treatment in people livin
Externí odkaz:
https://doaj.org/article/fc8b7adadb804deba9ac3db25272e2a9
Autor:
Jonathan Broomfield, Keith Abrams, Nick Latimer, Michela Guglieri, Mark Rutherford, Michael Crowther
Publikováno v:
Brain and Behavior, Vol 13, Iss 12, Pp n/a-n/a (2023)
Abstract Background Duchenne muscular dystrophy (DMD) is a rare, muscle‐degenerative disease predominantly affecting males. Natural history models capture the full disease pathway under current care and combine with estimates of new interventions
Externí odkaz:
https://doaj.org/article/af8c1ccc94e14c8383f076690e267936
Autor:
Natalie Bezman, Erin W Meermeier, Caleb Stein, Meaghen Sharik, Megan Du, Chang-Xin Shi, Yuan Xiao Zhu, Keith Abayasiriwardana, Timothy Fisher, Bas Baaten, Kristin Bompiani-Myers, P Leif Bergsagel, Marta Chesi
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/4fb39234917941daab7d6c48109eec89
Autor:
Adele Moatti, Dylan Silkstone, Taylor Martin, Keith Abbey, Kendall A Hutson, Douglas C Fitzpatrick, Carlton J Zdanski, Alan G Cheng, Frances S Ligler, Alon Greenbaum
Publikováno v:
iScience, Vol 26, Iss 6, Pp 106789- (2023)
Summary: Delivery of pharmaceutical therapeutics to the inner ear to treat and prevent hearing loss is challenging. Systemic delivery is not effective as only a small fraction of the therapeutic agent reaches the inner ear. Invasive surgeries to inje
Externí odkaz:
https://doaj.org/article/9b43e426dc0e496bb366311746e7fbe3
Autor:
Chinyereugo M. Umemneku-Chikere, Olubukola Ayodele, Marta Soares, Sam Khan, Keith Abrams, Rhiannon Owen, Sylwia Bujkiewicz
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Breast cancer is the fifth leading cause of cancer-related deaths worldwide. The randomized controlled trials (RCTs) of targeted therapies in human epidermal receptor 2 (HER2)–positive advanced breast cancer (ABC) have provided an evidence base for
Externí odkaz:
https://doaj.org/article/0185c2e8b67b473f855e88956ee6332f
Autor:
Kamlesh Khunti, Laura J Gray, Katherine Woolf, Luke Bryant, Robert C Free, Manish Pareek, Fatimah Wobi, Keith R Abrams, Laura Nellums, Amit Gupta, Catherine John, Martin D Tobin, Chris Orton, Sue Carr, David Ford, Christopher A Martin, Keith Abrams, Louise V Wain, Martin Tobin, Lucy Teece, Carl Melbourne, Edward Dove, Mayuri Gogoi, Ruby Reed-Berendt, Amani Al-Oraibi, Osama Hassan, Anna L Guyatt, I Chris McManus, Claire Garwood, Vishant Modhwadia, Ian Chris McManus, Janet Hood
Publikováno v:
BMJ Open, Vol 11, Iss 9 (2021)
Introduction The COVID-19 pandemic has resulted in significant morbidity and mortality and devastated economies globally. Among groups at increased risk are healthcare workers (HCWs) and ethnic minority groups. Emerging evidence suggests that HCWs fr
Externí odkaz:
https://doaj.org/article/2b16ed15616348da8b74c346256b9399
Autor:
Kamlesh Khunti, Katherine Woolf, Manish Pareek, Fatimah Wobi, Amit Gupta, Catherine Johns, Sue Carr, Chris McManus, Laura Gray, David Ford, Keith Abrams, Anna Guyatt, Louise Wain, Mayuri Gogoi, Amani Al-Oraibi, Laura B Nellums, Rob Free
Publikováno v:
BMJ Open, Vol 11, Iss 7 (2021)
Introduction As the world continues to grapple with the COVID-19 pandemic, emerging evidence suggests that individuals from ethnic minority backgrounds may be disproportionately affected. The United Kingdom Research study into Ethnicity And COVID-19
Externí odkaz:
https://doaj.org/article/dd54e1dbdf8442e08b3958a61c6a0d2a
Autor:
Kamlesh Khunti, Laura J Gray, David V Ford, Katherine Woolf, Manish Pareek, Keith R Abrams, David McAllister, Laura Nellums, Amit Gupta, Catherine John, Chris Orton, Catherine Johns, Sue Carr, Chris McManus, Laura Gray, David Ford, Christopher A Martin, Keith Abrams, Martin Tobin, Lucy Teece, Carl Melbourne, Anna Guyatt, Ibrahim Akubakar, Louise Wain, Edward Dove, Kamlesh Kunti, Robert Free
Publikováno v:
BMJ Open, Vol 11, Iss 6 (2021)
Introduction COVID-19 has spread rapidly worldwide, causing significant morbidity and mortality. People from ethnic minorities, particularly those working in healthcare settings, have been disproportionately affected. Current evidence of the associat
Externí odkaz:
https://doaj.org/article/ccfbcf66dbc24573a9570da0b717e8f2
Autor:
Reynaldo Martina, David Jenkins, Sylwia Bujkiewicz, Pascale Dequen, Keith Abrams, on behalf of GetReal Workpackage
Publikováno v:
Trials, Vol 19, Iss 1, Pp 1-12 (2018)
Abstract Background When designing studies it is common to search the literature to investigate variability estimates to use in sample size calculations. Proprietary data of previously designed trials in a particular indication are also used to obtai
Externí odkaz:
https://doaj.org/article/627fc62ac8e24f559f71f597fac8cbdc