Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Keith A. Spriggs"'
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Background Phytochemicals have become a growing source of alternative medicine in developing countries due to the poor prognosis, high cost of conventional pharmaceuticals, and undesirable effects associated with mainstream cancer treatment.
Externí odkaz:
https://doaj.org/article/d4a4bd356d7f4f3aa9d1713b6214d4cb
Autor:
Arif A. Surani, Keith A. Spriggs, Christoph Ufer, Christos Polytarchou, Cristina Montiel-Duarte
Publikováno v:
iScience, Vol 25, Iss 12, Pp 105519- (2022)
Summary: The relevance of minor transcription start sites in broad promoters is not well understood. We have studied AGAP2 expression in prostate cancer and chronic myeloid leukemia (CML), showing transcription is initiated from alternative transcrip
Externí odkaz:
https://doaj.org/article/3b2b90179d504e70b559ca56edf708b1
Autor:
Keith A. Spriggs, Ruman Rahman, Cameron Alexander, Ali Alazzo, Nurcan Gumus, Pratik Gurnani, Snjezana Stolnik
Publikováno v:
Journal of Materials Chemistry B. 10:236-246
The temporary silencing of disease-associated genes utilising short interfering RNA (siRNA) is a potent and selective route for addressing a wide range of life limiting disorders. However, the few clinically approved siRNA therapies rely on lipid bas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::173f3a444de7ee8bf29277414a0bcdf7
https://doi.org/10.1039/d1tb01793d
https://doi.org/10.1039/d1tb01793d
Autor:
Keith A Spriggs, Laura C Cobbold, Simon H Ridley, Mark Coldwell, Andrew Bottley, Martin Bushell, Anne E Willis, Kenneth Siddle
Publikováno v:
Nucleic Acids Research. 50:1796-1798
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77965b89bb1074706a51d3313c7f74e9
https://doi.org/10.1093/nar/gkac063
https://doi.org/10.1093/nar/gkac063
Autor:
Arif A. Surani, Keith A. Spriggs, Christoph Ufer, Christos Polytarchou, Cristina Montiel Duarte
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::afa328b3025be2edc83c45a264fd70ef
https://doi.org/10.2139/ssrn.4102618
https://doi.org/10.2139/ssrn.4102618
Autor:
Frances R Wadelin, Joel Fulton, Hilary M Collins, Nikolaos Tertipis, Andrew Bottley, Keith A Spriggs, Franco H Falcone, David M Heery
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0129297 (2015)
Externí odkaz:
https://doaj.org/article/08ee3cf0f78f4a109c22985a95f46940
Autor:
Frances R Wadelin, Joel Fulton, Hilary M Collins, Nikolaos Tertipis, Andrew Bottley, Keith A Spriggs, Franco H Falcone, David M Heery
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e58052 (2013)
Preferentially expressed antigen in melanoma (PRAME) has been described as a cancer-testis antigen and is associated with leukaemias and solid tumours. Here we show that PRAME gene transcription in leukaemic cell lines is rapidly induced by exposure
Externí odkaz:
https://doaj.org/article/b32dad261bba42caabba91579d7a833f
Publikováno v:
African Journal of Pharmacy and Pharmacology. 12:310-318
The cytotoxic activity of ethanol extract of Parquetina nigrescen was investigated using a (3-(4, 5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay, methylene blue and Trypan Blue exclusion assay on four human cancer cell lines, MCF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7066ee96afaf7ee5a5702c125467d87
https://doi.org/10.5897/ajpp2018.4947
https://doi.org/10.5897/ajpp2018.4947
Publikováno v:
PLoS ONE, Vol 5, Iss 9 (2010)
Alzheimer's disease (AD) is the main cause of dementia in our increasingly aging population. The debilitating cognitive and behavioral symptoms characteristic of AD make it an extremely distressing illness for patients and carers. Although drugs have
Externí odkaz:
https://doaj.org/article/21af6888f29b45a49080c31c310de211
Autor:
Steven M. Howdle, Muhammad Gulfam, Raphaël Riva, Keith A. Spriggs, Christine Jérôme, Patrícia F. Monteiro, Teresa Matini, Hilary M. Collins, Cameron Alexander
Publikováno v:
Biomaterials Science. 5:532-550
Polymer micelles have emerged as promising carriers for controlled release applications, however, several limitations of micelle-based drug delivery have also been reported. To address these issues, we have synthesized a functional biodegradable and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9a885b2c6374d1f5f1b592f8c7c5514
https://doi.org/10.1039/c6bm00888g
https://doi.org/10.1039/c6bm00888g