Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Keith A. Nair"'
Autor:
Georgios I. Laliotis, Evangelia Chavdoula, Maria D. Paraskevopoulou, Abdul Kaba, Alessandro La Ferlita, Satishkumar Singh, Vollter Anastas, Keith A. Nair, Arturo Orlacchio, Vasiliki Taraslia, Ioannis Vlachos, Marina Capece, Artemis Hatzigeorgiou, Dario Palmieri, Christos Tsatsanis, Salvatore Alaimo, Lalit Sehgal, David P. Carbone, Vincenzo Coppola, Philip N. Tsichlis
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-25 (2021)
IWS1 regulates multiple steps in RNA metabolism, including RNA elongation and alternative RNA splicing. Here the authors show that AKT3 phosphorylates IWS1, which alters U2AF2 RNA splicing and promotes growth of lung adenocarcinomas via a Sororin/ERK
Externí odkaz:
https://doaj.org/article/d561adaf19ee4c4ab175614033a5dedb
Autor:
Georgios I. Laliotis, Evangelia Chavdoula, Maria D. Paraskevopoulou, Abdul Kaba, Alessandro La Ferlita, Satishkumar Singh, Vollter Anastas, Keith A. Nair, Arturo Orlacchio, Vasiliki Taraslia, Ioannis Vlachos, Marina Capece, Artemis Hatzigeorgiou, Dario Palmieri, Christos Tsatsanis, Salvatore Alaimo, Lalit Sehgal, David P. Carbone, Vincenzo Coppola, Philip N. Tsichlis
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/5b5c850325bc4e3a8c96cdcd15103370
Autor:
Dario Palmieri, Ioannis S. Vlachos, Satishkumar Singh, Vasiliki Taraslia, David P. Carbone, Keith A. Nair Ii, Georgios I. Laliotis, Vincenzo Coppola, Arturo Orlacchio, Christos Tsatsanis, Marina Capece, Alessandro La Ferlita, Lalit Sehgal, Vollter Anastas, Artemis G. Hatzigeorgiou, Salvatore Alaimo, Abdul Kaba, Evangelia Chavdoula, Maria D. Paraskevopoulou, Philip N. Tsichlis
Publikováno v:
Nature Communications. 12
AKT-phosphorylated IWS1 regulates alternative RNA splicing via a pathway that is active in lung cancer. RNA-seq studies in lung adenocarcinoma cells lacking phosphorylated IWS1, identified a exon 2-deficient U2AF2 splice variant. Here, we show that e
Autor:
Georgios I. Laliotis, Evangelia Chavdoula, Maria D. Paraskevopoulou, Abdul D. Kaba, Alessandro La Ferlita, Satishkumar Singh, Vollter Anastas, Salvatore Alaimo, Arturo Orlacchio, Keith A. Nair, Vasiliki Taraslia, Ioannis Vlachos, Marina Capece, Artemis Hatzigeorgiou, Dario Palmieri, Christos Tsatsanis, Lalit Sehgal, David P. Carbone, Vincenzo Coppola, Philip N. Tsichlis
The authors have withdrawn their manuscript. While attempting to reproduce the data on the alternative splicing of exon 2 of U2AF2, they observed that the proposed splicing mechanism could not give rise to a functional U2AF2 protein. In addition, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96bd0c17abcc468f6c6412c4f547244f
https://doi.org/10.1101/2020.07.14.195297
https://doi.org/10.1101/2020.07.14.195297
Autor:
Keith Alan Nair, Bei Liu
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Endoplasmic reticulum stress occurs due to large amounts of misfolded proteins, hypoxia, nutrient deprivation, and more. The unfolded protein is a complex intracellular signaling network designed to operate under this stress. Composed of three indivi
Externí odkaz:
https://doaj.org/article/d6760abbaee7412199c7d65fe070fea6