Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Keith A. Charlton"'
Autor:
Cristina Rioja, Saskia C Van Wees, Keith A Charlton, Corné M J Pieterse, Oscar Lorenzo, Susana García-Sánchez
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54654 (2013)
Microbe-Associated Molecular Patterns and virulence effectors are recognized by plants as a first step to mount a defence response against potential pathogens. This recognition involves a large family of extracellular membrane receptors and other imm
Externí odkaz:
https://doaj.org/article/adcc005f0f094b53a9d80e2724b2b787
Autor:
Rebecca Parr, Heather M. Wallace, Hal Robinson, Gary A. Cameron, Thomas Engelhardt, Keith A. Charlton, Gillian Broadbent
Publikováno v:
Pharmaceutical and Biomedical Research.
Background: Fascia Iliaca Compartment Block (FICB) is commonly used in older patients to provide effective analgesia following hip fracture. Objectives: However, only limited Pharmacokinetic (PK) data about levobupivacaine are available to help clini
Publikováno v:
Archives of Clinical Microbiology.
Publikováno v:
Applied and Environmental Microbiology. 80:462-469
A number of bacteria, including pathogens like Pseudomonas aeruginosa , utilize homoserine lactones (HSLs) as quorum sensing (QS) signaling compounds and engage in cell-to-cell communication to coordinate their behavior. Blocking this bacterial commu
Autor:
Matthew C. Wright, Keith A. Charlton, James Shaw, Emma A. Fairhall, Guo Cai Huang, Karen Wallace, Sid C. Wright, Steven A. White, Alastair D. Burt
Publikováno v:
Toxicol. Res.
Reduction in the use of animals in toxicology is an important goal despite the continued need to assess drug and chemical safety in man. However, a limitation to in vitro screening for drug and chemical toxicity is the lack of available human hepatoc
Publikováno v:
Journal of Cell Science. 124:405-413
Elevated glucocorticoid levels result in the transdifferentiation of pancreatic acinar cells into hepatocytes through a process that requires a transient repression of WNT signalling upstream of the induction of C/EBP-β. However, the mechanism by wh
Publikováno v:
Toxicology. 278:277-287
Hepatocytes are the preparation of choice for Toxicological research in vitro. However, despite the fact that hepatocytes proliferate in vivo during liver regeneration, they are resistant to proliferation in vitro, do not tolerate sub-culture and ten
Autor:
Gillian Broadbent, Soumya Palliyil, Keith A. Charlton, David C. Cullen, Andrew J. Porter, Mohammed M. Al Qaraghuli
Publikováno v:
BMC Biotechnology
Background: Low molecular weight haptens (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7afffcd9010765bd5d1c2b246a89a6a8
https://strathprints.strath.ac.uk/62285/1/Al_Qaraghuli_etal_BMC_Biotechnology_2015_Defining_the_complementarities_between_antibodies_and_haptens.pdf
https://strathprints.strath.ac.uk/62285/1/Al_Qaraghuli_etal_BMC_Biotechnology_2015_Defining_the_complementarities_between_antibodies_and_haptens.pdf
Publikováno v:
Biosensors and Bioelectronics. 16:639-646
The complexity and expense of producing anti-hapten monoclonals via the traditional hybridoma route and the preferential selection of antibodies that recognise the conjugated form of the hapten, over antibodies that specifically recognise free hapten
Autor:
Matthew C. Wright, Emma A. Fairhall, Keith A. Charlton, Michelle Charles, Stefan A. Hoffmann, M. Richter, Claire Schwab, Christine J. Harrison, Katrin Zeilinger, Karen Wallace
Publikováno v:
Toxicology Research
The rat pancreatic “B-13” acinar cell is a stable progenitor cell line that differentiates into hepatocyte-like cells (B-13/H cells) in 2D un-coated plastic culture with simple culture media in response to glucocorticoid exposure. Examination of