Zobrazeno 1 - 10
of 199
pro vyhledávání: '"Keith A. Porter"'
Publikováno v:
Lifelines 2022.
Publikováno v:
Organic Letters. 16:940-943
A series of improvements to the standard solid phase peptide synthesis (SPPS) process allowing for significant gains in product purity along with only a 4 min standard cycle time and a 90% reduction in total waste produced is reported. For example, s
Autor:
Jessica M. Boname, Clemens Hermann, Keith M. Porter, Paul J. Lehner, John Trowsdale, Marian L. Burr, Karsten Skjødt, Michael E. Harbour, Peysh A. Patel, Louise H. Boyle, David Rhodes, Lidia M. Duncan
Publikováno v:
Boyle, L H, Hermann, C, Boname, J M, Porter, K M, Patel, P A, Burr, M L, Duncan, L M, Harbour, M E, Rhodes, D A, Skjødt, K, Lehner, P J & Trowsdale, J 2013, ' Tapasin-related protein TAPBPR is an additional component of the MHC class I presentation pathway ', Proceedings of the National Academy of Sciences of the United States of America, vol. 110, no. 9, pp. 3465-3470 . https://doi.org/10.1073/pnas.1222342110
Tapasin is an integral component of the peptide-loading complex (PLC) important for efficient peptide loading onto MHC class I molecules. We investigated the function of the tapasin-related protein, TAPBPR. Like tapasin, TAPBPR is widely expressed, I
Autor:
Isabel, Huang-Doran, Louise S, Bicknell, Francis M, Finucane, Nuno, Rocha, Keith M, Porter, Y C Loraine, Tung, Ferenc, Szekeres, Anna, Krook, John J, Nolan, Mark, O'Driscoll, Michael, Bober, Stephen, O'Rahilly, Andrew P, Jackson, Robert K, Semple, Natalia, Volevodz
Publikováno v:
Huang-Doran, I, Bicknell, L S, Finucane, F M, Rocha, N, Porter, K M, Tung, Y C L, Szekeres, F, Krook, A, Nolan, J J, O'Driscoll, M, Bober, M, O'Rahilly, S & Jackson, A P & Semple, R K 2011, ' Genetic Defects in Human Pericentrin Are Associated With Severe Insulin Resistance and Diabetes ', Diabetes, vol. 60, no. 3, pp. 925-935 . https://doi.org/10.2337/db10-1334
Diabetes
Diabetes
OBJECTIVE Genetic defects in human pericentrin (PCNT), encoding the centrosomal protein pericentrin, cause a form of osteodysplastic primordial dwarfism that is sometimes reported to be associated with diabetes. We thus set out to determine the preva
Autor:
Inês Barroso, Victoria E. R. Parker, J. Kirk, Keith M. Porter, Christian J. Hendriksz, Robert K. Semple, Stephen O'Rahilly
Publikováno v:
Journal of Inherited Metabolic Disease
In Npc1 null mice, a model for Niemann Pick Disease Type C1, it has been reported that hepatocyte insulin receptor function is significantly impaired, consistent with growing evidence that membrane fluidity and microdomain structure have an important
Autor:
Keith S. Porter, Laurence Smith
Publikováno v:
Regional Environmental Change. 10:311-326
Primary purposes for catchment management are to establish a cost-effective allocation and use of its water resources and to most effectively apply measures to protect the quantity and quality of the water produced by the catchment. For the latter pu
Autor:
Scott R. White, Haim Weissman, Keith A. Porter, Gerald O. Wilson, Nancy R. Sottos, Jeffrey S. Moore
Publikováno v:
Advanced Synthesis & Catalysis. 351:1817-1825
The stability of second generation Grubbs� alkylidenes to primary amines relative to the first generation derivatives is investigated. For both Grubbsalkylidene derivatives, the tricyclohexyl- phosphine (PCy3) ligand is displaced by n-butyl- A and
Autor:
Keith A. Porter, Anthony C. Willis, Xiangting Zhou, Elizabeth H. Krenske, Michelle L. Coote, Michelle Weir, S. Bruce Wild
Publikováno v:
Organometallics. 27:5099-5107
A new method for the asymmetric synthesis of As-chiral tertiary arsines is described. The addition at −95 °C of n-butyllithium to a dichloromethane solution of a phosphine-stabilized arsenium salt of the type (±)-[R3P→AsMePh]PF6, where R3P is a
The central focus of this volume is a critical comparative analysis of the key drivers for water resource management and the provision of clean water – governance systems and institutional and legal arrangements. The authors present a systematic an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03523998f34cd77ea5f5633b6cceac12
https://doi.org/10.4324/9780203129159
https://doi.org/10.4324/9780203129159