Zobrazeno 1 - 10
of 285
pro vyhledávání: '"Keith, Wheatley"'
Autor:
Nicola Fenwick, Rebekah Weston, Keith Wheatley, Jodie Hodgson, Lynley Marshall, Martin Elliott, Guy Makin, Antony Ng, Bernadette Brennan, Stephen Lowis, Jenny Adamski, John Paul Kilday, Rachel Cox, Mike Gattens, Andrew Moore, Toby Trahair, Milind Ronghe, Martin Campbell, Helen Campbell, Molly W. Williams, Maria Kirby, Natasha Van Eijkelenburg, Jennifer Keely, Ugo Scarpa, Victoria Stavrou, Livingstone Fultang, Sarah Booth, Paul Cheng, Carmela De Santo, Francis Mussai
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundThe survival for many children with relapsed/refractory cancers remains poor despite advances in therapies. Arginine metabolism plays a key role in the pathophysiology of a number of pediatric cancers. We report the first in child study of
Externí odkaz:
https://doaj.org/article/4902b15b11094343be86c12a848d2cb8
Autor:
David Jayne, Michael Walsh, Peter A Merkel, Chen Au Peh, Wladimir Szpirt, Xavier Puéchal, Shouichi Fujimoto, Carmel Hawley, Nader Khalidi, Rachel Jones, Oliver Flossmann, Ron Wald, Louis Girard, Adeera Levin, Gina Gregorini, Lorraine Harper, William Clark, Christian Pagnoux, Ulrich Specks, Lucy Smyth, Toshiko Ito-Ihara, Janak de Zoysa, Biljana Brezina, Andrea Mazzetti, Carol A McAlear, Donna Reidlinger, Samir Mehta, Natalie Ives, Elizabeth A Brettell, Hugh Jarrett, Keith Wheatley, Elizabeth Broadhurst, Alina Casian, Charles D Pusey
Publikováno v:
Health Technology Assessment, Vol 26, Iss 38 (2022)
Background: Anti-neutrophil cytoplasm antibody-associated vasculitis is a multisystem, autoimmune disease that causes organ failure and death. Physical removal of pathogenic autoantibodies by plasma exchange is recommended for severe presentations, a
Externí odkaz:
https://doaj.org/article/d0a874aa7a77433586be6d35e45e9780
Autor:
Jennifer Anderton, Veronica Moroz, Perrine Marec-Bérard, Nathalie Gaspar, Valerie Laurence, Javier Martín-Broto, Ana Sastre, Hans Gelderblom, Cormac Owens, Sophie Kaiser, Melissa Fernández-Pinto, Nicola Fenwick, Abigail Evans, Sandra Strauss, Jeremy Whelan, Keith Wheatley, Bernadette Brennan
Publikováno v:
Trials, Vol 21, Iss 1, Pp 1-9 (2020)
Abstract Background Although there have been multiple randomised trials in newly diagnosed Ewing sarcoma family of tumours (ESFT) and these have been conducted over many years and involved many international cooperative groups, the outcomes for all s
Externí odkaz:
https://doaj.org/article/3811d226d5e147d297ab7d33074ca8fc
Autor:
Sarah Alexander, Anne Aupérin, Simon Bomken, Monika Csóka, Bernarda Kazanowska, Alan K Chiang, Mara Andres, Anne Uyttebroeck, G A Amos Burke, József Zsiros, Marta Pillon, Catherine M Bollard, Lara Mussolin, Jaime Verdu-Amoros, Bénédicte Neven, Donald A Barkauskas, Keith Wheatley, Catherine Patte, Thomas G Gross, Véronique Minard-Colin
Publikováno v:
The Lancet Haematology. 10:e445-e457
Autor:
Darren Green, Diana Vassallo, Kelly Handley, Natalie Ives, Keith Wheatley, Constantina Chrysochou, Janet Hegarty, Julian Wright, Jon Moss, Rajan K. Patel, Chris Deighan, John Webster, Peter Rowe, Sue Carr, Jenny Cross, Jamie O’Driscoll, Raj Sharma, Patrick Mark, Philip A. Kalra
Publikováno v:
BMC Nephrology, Vol 20, Iss 1, Pp 1-9 (2019)
Abstract Background The ASTRAL trial showed no difference in clinical outcomes between medical therapy and revascularization for atherosclerotic renal vascular disease (ARVD). Here we report a sub-study using echocardiography to assess differences in
Externí odkaz:
https://doaj.org/article/87f44cc1f57e4768a0a2b65742e47193
Autor:
Catherine M. Sackley, Christina H. Smith, Caroline E. Rick, Marian C. Brady, Natalie Ives, Smitaa Patel, Rebecca Woolley, Francis Dowling, Ramilla Patel, Helen Roberts, Sue Jowett, Keith Wheatley, Debbie Kelly, Gina Sands, Carl E. Clarke, on behalf of the PD COMM Pilot Collaborative Group
Publikováno v:
Pilot and Feasibility Studies, Vol 4, Iss 1, Pp 1-10 (2018)
Abstract Background Speech-related problems are common in Parkinson’s disease (PD), but there is little evidence for the effectiveness of standard speech and language therapy (SLT) or Lee Silverman Voice Treatment (LSVT LOUD®). Methods The PD COMM
Externí odkaz:
https://doaj.org/article/0f4d30211fe7407ebe9084a999f6a01f
Autor:
Lynn Quek, Paul Ferguson, Marlen Metzner, Ikhlaaq Ahmed, Alison Kennedy, Catherine Garnett, Sally Jeffries, Claudia Walter, Kim Piechocki, Adele Timbs, Robert Danby, Manoj Raghavan, Andrew Peniket, Mike Griffiths, Andrew Bacon, Janice Ward, Keith Wheatley, Paresh Vyas, Charles Craddock
Publikováno v:
Blood Advances, Vol 1, Iss 3, Pp 193-204 (2016)
Abstract: Disease relapse is the major cause of treatment failure after allogeneic stem cell transplantation (allo-SCT) in acute myeloid leukemia (AML). To identify AML-associated genes prognostic of AML relapse post–allo-SCT, we resequenced 35 gen
Externí odkaz:
https://doaj.org/article/c7aa4ecc15494ffc87dd288a52539336
Autor:
Jim Murray, Guy Pratt, Abe Jacob, Fiona Clark, Rachel Blundred, Sonia Fox, Rebecca Bishop, Keith Wheatley, Farhat Khanim, Chris Bunce, Mark Drayson
Publikováno v:
Contemporary Clinical Trials Communications, Vol 14, Iss , Pp - (2019)
We previously reported the safety and efficacy of low dose BaP [Bezafibrate (Bez) and Medroxyprogesterone acetate (MPA)] in 20 acute myeloid leukaemia (AML) patients for whom chemotherapy was not an option. This study provided evidence that BaP had a
Externí odkaz:
https://doaj.org/article/f1551d62f7a546c7abba645fbac2c2f3
Autor:
Nicholas JA Webb, Rebecca L Woolley, Tosin Lambe, Emma Frew, Elizabeth A Brettell, Emma N Barsoum, Richard S Trompeter, Carole Cummins, Keith Wheatley, Natalie J Ives
Publikováno v:
Health Technology Assessment, Vol 23, Iss 26 (2019)
Background: The optimal corticosteroid regimen for treating the presenting episode of steroid-sensitive nephrotic syndrome (SSNS) remains uncertain. Most UK centres use an 8-week regimen, despite previous systematic reviews indicating that longer reg
Externí odkaz:
https://doaj.org/article/70b1a7df8be04f38ab82cff77133acb4
Autor:
Paresh Vyas, Jamie D. Cavenagh, Michael Dennis, Shamyla Siddique, Richard J. Kelly, Srinivas P. Pillai, Mary Frances McMullin, Keith Wheatley, Louise Dudley, Sandeep Nagra, Manoj Raghavan, Angela Hamblin, Alison Kennedy, Natalia Garcia-Martin, Marlen Metzner, Corran Roberts, Emma Gbandi, Paul Ferguson, Lynn Swun Quek, Aimee E. Houlton, Charles F. Craddock
Table S3. Variants detected by NGS targeted re-sequencing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30cac8136a16ee1bad22e1c2d07a962d
https://doi.org/10.1158/1078-0432.22468974.v1
https://doi.org/10.1158/1078-0432.22468974.v1