Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Keith, Wafford"'
Autor:
Paula de Oliveira, Claire Cella, Nicolas Locker, Kiran K. G. Ravindran, Agampodi Mendis, Keith Wafford, Gary Gilmour, Derk-Jan Dijk, Raphaelle Winsky-Sommerer
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 42(16)
Several cellular pathways contribute to neurodegenerative tauopathy-related disorders. Microglial activation, a major component of neuroinflammation, is an early pathologic hallmark that correlates with cognitive decline, while the unfolded protein r
Publikováno v:
Advances in Pharmacological Sciences, Vol 2012 (2012)
Externí odkaz:
https://doaj.org/article/8ca1d796c3e14ec6aad8406dcb7bf27c
Publikováno v:
Advances in Pharmacological Sciences
Autor:
Dianne R, Peden, Caroline M, Petitjean, Murray B, Herd, Murat S, Durakoglugil, Thomas W, Rosahl, Keith, Wafford, Gregg E, Homanics, Delia, Belelli, Jean-Marc, Fritschy, Jeremy J, Lambert
Publikováno v:
The Journal of physiology. 586(4)
Thalamic ventrobasal (VB) relay neurones express multiple GABA(A) receptor subtypes mediating phasic and tonic inhibition. During postnatal development, marked changes in subunit expression occur, presumably reflecting changes in functional propertie
Anxiogenic properties of an inverse agonist selective for alpha3 subunit-containing GABA A receptors
Autor:
John R, Atack, Peter H, Hutson, Neil, Collinson, George, Marshall, Graham, Bentley, Christopher, Moyes, Susan M, Cook, Ian, Collins, Keith, Wafford, Ruth M, McKernan, Gerard R, Dawson
Publikováno v:
British journal of pharmacology. 144(3)
Alpha3IA (6-(4-pyridyl)-5-(4-methoxyphenyl)-3-carbomethoxy-1-methyl-1H-pyridin-2-one) is a pyridone with higher binding and functional affinity and greater inverse agonist efficacy for GABA(A) receptors containing an alpha3 rather than an alpha1, alp