Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Keith, Nieforth"'
Autor:
Rong Chen, Alan Schumitzky, Alona Kryshchenko, Keith Nieforth, Michael Tomashevskiy, Shuhua Hu, Romain Garreau, Julian Otalvaro, Walter Yamada, Michael N. Neely
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 13, Iss 5, Pp 759-780 (2024)
Abstract Inspired from quantum Monte Carlo, by sampling discrete and continuous variables at the same time using the Metropolis–Hastings algorithm, we present a novel, fast, and accurate high performance Monte Carlo Parametric Expectation Maximizat
Externí odkaz:
https://doaj.org/article/db51cc11e3bb4c799334eb1b26b3456e
Autor:
Sushmita Chanda, Keith Nieforth, Dymphy Huntjens, Matthew McClure, John P. DeVincenzo, Patrick F. Smith, Kashyap Patel, Leo Beigelman, Lawrence M. Blatt, Carl M. J. Kirkpatrick, Qingling Zhang, Julian Symons, John Fry
Publikováno v:
Journal of Antimicrobial Chemotherapy. 74:442-452
Background Respiratory syncytial virus (RSV) causes high morbidity, with mortality rates approaching or exceeding that of influenza in adult and infant patient populations, respectively. Lumicitabine (ALS-008176 or JNJ-64041575) is an oral nucleoside
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e24737e190892f675d9ef2f64fd5a68
https://doi.org/10.1093/jac/dky415
https://doi.org/10.1093/jac/dky415
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology
A visual predictive check (VPC) is a common diagnostic procedure for population pharmacometric models. Typically, VPCs are generated by specifying intervals, or "bins", of an independent variable (e.g., time). However, bin specification is not always
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c6dc798295d086d42002ce6ca3c73f2
http://europepmc.org/articles/PMC6202468
http://europepmc.org/articles/PMC6202468
Autor:
Georgina Dall, Richard E. Nelson, David Bin-Chia Wu, Mohamed A. Kamal, Carl M. J. Kirkpatrick, Aaron W. C. Kamauu, Craig R Rayner, Kenneth K.C. Lee, Nathorn Chaiyakunapruk, Stephen Toovey, Chayanin Pratoomsoot, Keith Nieforth, David C. M. Kong, Huey Yi Chong, Patrick F. Smith
Publikováno v:
British Journal of Clinical Pharmacology. 83:1580-1594
Aims A modular interdisciplinary platform was developed to investigate the economic impact of oseltamivir treatment by dosage regimen under simulated influenza pandemic scenarios. Methods The pharmacology module consisted of a pharmacokinetic distrib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3aff16c78509adda51abf9b986d817fe
https://doi.org/10.1111/bcp.13229
https://doi.org/10.1111/bcp.13229
Autor:
Mohamed A. Kamal, David C. M. Kong, Craig R Rayner, Nathorn Chaiyakunapruk, Georgina Dall, David Bin-Chia Wu, Chayanin Pratoomsoot, Stephen Toovey, Aaron Kamauu, Huey Yi Chong, Richard E. Nelson, Kenneth K.C. Lee, Patrick F. Smith, Carl M. J. Kirkpatrick, Keith Nieforth
Publikováno v:
Epidemiol Infect
Simulation models are used widely in pharmacology, epidemiology and health economics (HEs). However, there have been no attempts to incorporate models from these disciplines into a single integrated model. Accordingly, we explored this linkage to eva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6469322f56ca401ac9fb2d5b09e62a13
https://europepmc.org/articles/PMC9134563/
https://europepmc.org/articles/PMC9134563/
Autor:
Iain Tatt, Miriam Adamcova, Patricia Schlagenhauf, Stephen Toovey, Gabriel Schnetzler, Keith Nieforth, Danitza Tomianovic, Patrick F. Smith
Publikováno v:
Travel Medicine and Infectious Disease. 12:726-732
Summary Background Chemoprophylaxis against falciparum malaria is recommended for travellers from non-endemic countries to malarious destinations, but debate continues on benefit, especially with regard to mefloquine. Quantification of benefit for tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3c79ae8660a91bea814d6dfe2891fea
https://doi.org/10.1016/j.tmaid.2014.08.005
https://doi.org/10.1016/j.tmaid.2014.08.005
Autor:
Richard Peck, Nenad Sarapa, Michael Derks, Hisham Y. Abdallah, Bruno Boutouyrie, Patrick F. Smith, Keith Nieforth
Publikováno v:
British Journal of Clinical Pharmacology. 76:841-845
How does one define the discipline of clinical pharmacology? This has been a subject for much debate in recent literature [1–5]. The historical discipline of clinical pharmacology is one of integrating information across disciplines, requiring a br
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3f92e834a538e22506a86daf39c4ab3
https://doi.org/10.1111/bcp.12119
https://doi.org/10.1111/bcp.12119
Autor:
David J Moore, Li Yu, Peter N. Morcos, Mika Sato, Meret Martin-Facklam, Matt Whayman, Katja Heinig, Elena Guerini, Dieter Muri, Alex Phipps, Kosuke Kawashima, Katrijn Bogman, Keith Nieforth, Hisakazu Chugai Seiyaku Kabushiki Kaisha Katsuki
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 47(3)
1. Alectinib is a highly selective, central nervous system-active small molecule anaplastic lymphoma kinase inhibitor. 2. The absolute bioavailability, metabolism, excretion and pharmacokinetics of alectinib were studied in a two-period single-sequen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd8e36d67c0f387a5c770b980d4be750
https://pubmed.ncbi.nlm.nih.gov/27180975
https://pubmed.ncbi.nlm.nih.gov/27180975
Autor:
Mohamed A, Kamal, Patrick F, Smith, Nathorn, Chaiyakunapruk, David B C, Wu, Chayanin, Pratoomsoot, Kenneth K C, Lee, Huey Yi, Chong, Richard E, Nelson, Keith, Nieforth, Georgina, Dall, Stephen, Toovey, David C M, Kong, Aaron, Kamauu, Carl M, Kirkpatrick, Craig R, Rayner
Publikováno v:
British journal of clinical pharmacology. 83(7)
A modular interdisciplinary platform was developed to investigate the economic impact of oseltamivir treatment by dosage regimen under simulated influenza pandemic scenarios.The pharmacology module consisted of a pharmacokinetic distribution of oselt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b396e144c09caa595febd5cb1d8ddd80
https://pubmed.ncbi.nlm.nih.gov/28176362
https://pubmed.ncbi.nlm.nih.gov/28176362
Autor:
Sushmita Chanda, Jolanta Bernatoniene, Keith Nieforth, Michael Fayon, Kashyap Patel, Kathia Luciani, Adam Finn, Leonid Beigelman, Julian Symons, Lawrence M. Blatt, Abbie Oey, Patrick F. Smith, Rattapon Uppala, Matthew C. McClure, Qingling Zhang, John Fry
Publikováno v:
Open Forum Infectious Diseases. 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e0ae3e2f162bce22ede3b89d1b40a93
https://doi.org/10.1093/ofid/ofw172.1052
https://doi.org/10.1093/ofid/ofw172.1052