Clinical Snapshot of Group A Streptococcal Isolates from an Australian Tertiary Hospital

Autor: Phoebe K. Shaw, Andrew J. Hayes, Maree Langton, Angela Berkhout, Keith Grimwood, Mark R. Davies, Mark J. Walker, Stephan Brouwer

Publikováno v: Pathogens, Vol 13, Iss 11, p 956 (2024)

Streptococcus pyogenes (Group A Streptococcus, GAS) is a human-restricted pathogen that causes a wide range of diseases from pharyngitis and scarlet fever to more severe, invasive infections such as necrotising fasciitis and streptococcal toxic shock

Externí odkaz: https://doaj.org/article/fac9282c98c04531ba4a75998629c59a

Detection of Streptococcus pyogenes M1UK in Australia and characterization of the mutation driving enhanced expression of superantigen SpeA

Autor: Mark R. Davies, Nadia Keller, Stephan Brouwer, Magnus G. Jespersen, Amanda J. Cork, Andrew J. Hayes, Miranda E. Pitt, David M. P. De Oliveira, Nichaela Harbison-Price, Olivia M. Bertolla, Daniel G. Mediati, Bodie F. Curren, George Taiaroa, Jake A. Lacey, Helen V. Smith, Ning-Xia Fang, Lachlan J. M. Coin, Kerrie Stevens, Steven Y. C. Tong, Martina Sanderson-Smith, Jai J. Tree, Adam D. Irwin, Keith Grimwood, Benjamin P. Howden, Amy V. Jennison, Mark J. Walker

Publikováno v: Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)

A variant of group A Streptococcus serotype M1 (UK) has been increasingly reported and can be differentiated from the global variant by its overexpression of the superantigen SpeA. Here, Davies et al probe the mechanism behind enhanced SpeA expressio

Externí odkaz: https://doaj.org/article/c8e8696ec17643b4a4f2990cdf959bbe

Quality standards for managing children and adolescents with bronchiectasis: an international consensus

Autor: Anne B. Chang, Jeanette Boyd, Andrew Bush, Adam T. Hill, Zena Powell, Angela Zacharasiewicz, Efthymia Alexopoulou, James D. Chalmers, Andrew J. Collaro, Carolina Constant, Konstantinos Douros, Rebecca Fortescue, Matthias Griese, Jonathan Grigg, Andreas Hector, Bulent Karadag, Oleksandr Mazulov, Fabio Midulla, Alexander Moeller, Marijke Proesmans, Christine Wilson, Stephanie T. Yerkovich, Ahmad Kantar, Keith Grimwood

Publikováno v: Breathe, Vol 18, Iss 3 (2022)

The global burden of bronchiectasis in children and adolescents is being recognised increasingly. However, marked inequity exists between, and within, settings and countries for resources and standards of care afforded to children and adolescents wit

Externí odkaz: https://doaj.org/article/0aa6dce8670849429657afe38267af0d

Study Protocol for Preventing Early-Onset Pneumonia in Young Children Through Maternal Immunisation: A Multi-Centre Randomised Controlled Trial (PneuMatters)

Autor: Anne B. Chang, Maree Toombs, Mark D. Chatfield, Remai Mitchell, Siew M. Fong, Michael J. Binks, Heidi Smith-Vaughan, Susan J. Pizzutto, Karin Lust, Peter S. Morris, Julie M. Marchant, Stephanie T. Yerkovich, Hannah O'Farrell, Paul J. Torzillo, Carolyn Maclennan, David Simon, Holger W. Unger, Hasthika Ellepola, Jens Odendahl, Helen S. Marshall, Geeta K. Swamy, Keith Grimwood

Publikováno v: Frontiers in Pediatrics, Vol 9 (2022)

Background: Preventing and/or reducing acute lower respiratory infections (ALRIs) in young children will lead to substantial short and long-term clinical benefits. While immunisation with pneumococcal conjugate vaccines (PCV) reduces paediatric ALRIs

Externí odkaz: https://doaj.org/article/177b649bdd9c4ed383042db29e6e9ad2

Queensland Pediatric Sepsis Breakthrough Collaborative: Multicenter Observational Study to Evaluate the Implementation of a Pediatric Sepsis Pathway Within the Emergency Department

Autor: Amanda Harley, MN, Paula Lister, PhD, Patricia Gilholm, PhD, Michael Rice, MN, Bala Venkatesh, MD, Amy N.B. Johnston, PhD, Debbie Massey, PhD, Adam Irwin, PhD, Kristen Gibbons, PhD, Luregn J. Schlapbach, PhD, on behalf of the Queensland Statewide Sepsis Collaborative, Luregn Schlapbach, Amanda Harley, Adam Irwin, Nicolette Graham, Fiona Thomson, Kieran Owen, Kirsten Garrish, Emma Sampson, Debbie Long, Shane George, Keith Grimwood, Christa Bell, Bethany Semple, Claire Adams, Josea Brown, Louise Maloney, Paula Lister, Scott Schofield, Clare Thomas, Liam Dejong, Esther Bently, Lambros Halkidis, Cheryl Bird, Matthew Smith, Pia Alexander, Laura Davidson-West, Titiosibina Ebenezer Adegbija, Alice Brandt, Bree Walker, Andrea McLucas, Adam Philip Michael, Yulia Sugeng, Samantha Hoole, Candice Bauer, John Sutherland, Douglas Gordon Thomas, David Van der Walt, Jessica Hulme, Kerrie Burke, Helena Cooney, Doug Morel, Louise O’Riordan, Samantha Fairless, Megan Bool, Nandini Choudary, Shalini Arora, Ben Lawton, Jo Farrell, Penelope Prasad, Rudesh Prasad, Laura O’Connor, Timothy Butters, Peter Kennedy, Hanh Pham, Maya Aoude, Sara Blundell, Natasha Willmett, Louise McGrath, Karen Smith, Kate Weller, Trina Maturanec, Michael Rice, Balasubramanian Venkatesh, Paul Lane, Lyndell Redpath, Robert Seaton, Donna Mason, Naitik Mehta, Vikrant Kalke, Damian Jones, Mathew Ames, Mary Steele, Amy Wilkinson, Kristen Gibbons, Patricia Gilholm, Endrias Ergetu, Rachel Treadwell, Tahlia Van Raders, Jessicah Minogue

Publikováno v: Critical Care Explorations, Vol 3, Iss 11, p e0573 (2021)

OBJECTIVES:. To evaluate the implementation of a pediatric sepsis pathway in the emergency department as part of a statewide quality improvement initiative in Queensland, Australia. DESIGN:. Multicenter observational prospective cohort study. SETTING

Externí odkaz: https://doaj.org/article/b3f366b90c604ecaa49b548e686ff111