Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Keith, Fraser"'
Autor:
Shounak Banerjee, Keith Fraser, Donna E. Crone, Jinal C. Patel, Sarah E. Bondos, Christopher Bystroff
Publikováno v:
Sensors, Vol 24, Iss 19, p 6380 (2024)
The leave-one-out (LOO) green fluorescent protein (GFP) approach to biosensor design combines computational protein design with split protein reconstitution. LOO-GFPs reversibly fold and gain fluorescence upon encountering the target peptide, which c
Externí odkaz:
https://doaj.org/article/e4ba448fa8524e7d80f3b477f7b255f3
Autor:
Keith Fraser, Arran Hamlet, Kévin Jean, Daniel Garkauskas Ramos, Alessandro Romano, Jennifer Horton, Laurence Cibrelus, Neil M Ferguson, Katy A M Gaythorpe
Publikováno v:
PLOS Global Public Health, Vol 4, Iss 11, p e0003781 (2024)
Yellow fever (YF), a vector-borne viral hemorrhagic fever, is endemic in tropical regions of Africa and South America, with large vaccination programmes being used for control. However, significant outbreaks have occurred in recent years. Data on inf
Externí odkaz:
https://doaj.org/article/ec232319c65b48a3a69eff8cf8c671e1
Autor:
Paul S. Kwon, Shirley Xu, Hanseul Oh, Seok-Joon Kwon, Andre L. Rodrigues, Maisha Feroz, Keith Fraser, Peng He, Fuming Zhang, Jung Joo Hong, Robert J. Linhardt, Jonathan S. Dordick
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-8 (2023)
Suramin, a polysulfated synthetic drug, binds to the ACE2 receptor and heparan sulfate binding sites on SARS-CoV-2 RBDs with preferential binding for Omicron RBD and inhibition of infection by the Omicron variant in vitro.
Externí odkaz:
https://doaj.org/article/f9c4ce0ff01c4a649d774200f246e2fd
Autor:
Javan Chanda, Joseph Wagman, Benjamin Chanda, Tresford Kaniki, Mirabelle Ng’andu, Rayford Muyabe, Mwansa Mwenya, Jimmy Sakala, John Miller, Gift Mwaanga, Limonty Simubali, Monicah Mirai Mburu, Edgar Simulundu, Alice Mungo, Keith Fraser, Lazaro Mwandigha, Ruth Ashton, Joshua Yukich, Angela F. Harris, Thomas R. Burkot, Erica Orange, Megan Littrell, Julian Entwistle
Publikováno v:
Malaria Journal, Vol 22, Iss 1, Pp 1-15 (2023)
Abstract Background Attractive targeted sugar bait (ATSB) stations are a promising new approach to malaria vector control that could compliment current tools by exploiting the natural sugar feeding behaviors of mosquitoes. Recent proof of concept wor
Externí odkaz:
https://doaj.org/article/fee5d3ba750b4b228ccaa116c0849628
Autor:
Stacyann Bailey, Keith Fraser
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
The gut microbiome has been implicated in a multitude of human diseases, with emerging evidence linking its microbial diversity to osteoporosis. This review article will explore the molecular mechanisms underlying perturbations in the gut microbiome
Externí odkaz:
https://doaj.org/article/dc3e277e62eb4c2f8fe11578781d8c7f
Autor:
Katy A.M. Gaythorpe, Rich G. Fitzjohn, Wes Hinsley, Natsuko Imai, Edward S. Knock, Pablo N. Perez Guzman, Bimandra Djaafara, Keith Fraser, Marc Baguelin, Neil M. Ferguson
Publikováno v:
Epidemics, Vol 43, Iss , Pp 100676- (2023)
In an emergency epidemic response, data providers supply data on a best-faith effort to modellers and analysts who are typically the end user of data collected for other primary purposes such as to inform patient care. Thus, modellers who analyse sec
Externí odkaz:
https://doaj.org/article/5e16eb6416804431a46246dc22c28454
Autor:
Jonathan A. Polonsky, Sangeeta Bhatia, Keith Fraser, Arran Hamlet, Janetta Skarp, Isaac J. Stopard, Stéphane Hugonnet, Laurent Kaiser, Christian Lengeler, Karl Blanchet, Paul Spiegel
Publikováno v:
Infectious Diseases of Poverty, Vol 11, Iss 1, Pp 1-19 (2022)
Abstract Background Non-pharmaceutical interventions (NPIs) are a crucial suite of measures to prevent and control infectious disease outbreaks. Despite being particularly important for crisis-affected populations and those living in informal settlem
Externí odkaz:
https://doaj.org/article/1def88efb6a44e058da6a695779d6307
Autor:
Abinaya Badri, Asher Williams, Adeola Awofiranye, Payel Datta, Ke Xia, Wenqin He, Keith Fraser, Jonathan S. Dordick, Robert J. Linhardt, Mattheos A. G. Koffas
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Chondroitin sulfate (CS) is a type of sulfated glycosaminoglycan that is manufactured by extraction from animal tissues for the treatment of osteoarthritis and in drug delivery applications. Here, the authors report the development of single microbia
Externí odkaz:
https://doaj.org/article/2577cbcebedc48b7b753dd7ad282e97c
Autor:
Shaokang Ren, Keith Fraser, Lili Kuo, Neha Chauhan, Addison T. Adrian, Fuming Zhang, Robert J. Linhardt, Paul S. Kwon, Xing Wang
Publikováno v:
Nat Protoc
Emerging viral diseases can substantially threaten national and global public health. Central to our ability to successfully tackle these diseases is the need to quickly detect the causative virus and neutralize it efficiently. Here we present the ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75597897aaf15670596f672e9c914fdf
https://doi.org/10.1038/s41596-021-00641-y
https://doi.org/10.1038/s41596-021-00641-y
Autor:
Natsuko Imai, Thomas Rawson, Edward S Knock, Raphael Sonabend, Yasin Elmaci, Pablo N Perez-Guzman, Lilith K Whittles, Divya Thekke Kanapram, Katy AM Gaythorpe, Wes Hinsley, Bimandra A Djaafara, Haowei Wang, Keith Fraser, Richard G FitzJohn, Alexandra B Hogan, Patrick Doohan, Azra C Ghani, Neil M Ferguson, Marc Baguelin, Anne Cori
Publikováno v:
e183
e174
e174
BackgroundThe UK was the first country to start national COVID-19 vaccination programmes, initially administering doses 3-weeks apart. However, early evidence of high vaccine effectiveness after the first dose and the emergence of the Alpha variant p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f747ed4c854013082a9aad84a2d84e1a
https://doi.org/10.1101/2022.08.08.22278528
https://doi.org/10.1101/2022.08.08.22278528
