Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Keith, Abe"'
Autor:
Malia Rasa MD, James Musgrave MD, Keith Abe MD, Len Tanaka MD, Konstantine Xoinis MD, Bruce Shiramizu MD, Gretchen Foskett MD, Rhiana Lau MD
Publikováno v:
Journal of Investigative Medicine High Impact Case Reports, Vol 5 (2017)
Hemolytic uremic syndrome (HUS) can be classified as typical and atypical, and the treatment recommendations currently differ between the 2 types. Eculizumab is recommended as first-line treatment for atypical HUS; however, its use in typical HUS has
Externí odkaz:
https://doaj.org/article/a07ccabda34c4df2a092ad3e128164f3
Autor:
Laurie H Seaver, Xue-Ying He, Keith Abe, Tina Cowan, Gregory M Enns, Lawrence Sweetman, Manfred Philipp, Sansan Lee, Mazhar Malik, Song-Yu Yang
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27348 (2011)
Hydroxysteroid (17beta) dehydrogenase 10 (HSD10) is a mitochondrial multifunctional enzyme encoded by the HSD17B10 gene. Missense mutations in this gene result in HSD10 deficiency, whereas a silent mutation results in mental retardation, X-linked, sy
Externí odkaz:
https://doaj.org/article/4d1b3092eec5405f92855c1277622af9
Autor:
Nelly Gutierrez Martinez, Surabhi Khasgiwala, Len Tanaka, Aileen Tanaka, Konstantine Xoinis, John Harrington, Keith Abe, Rupert Chang, Prashant Purohit
Publikováno v:
Critical Care Medicine. 50:395-395
Autor:
Keith Abe, John Harrington, Marina Nogues, Rupert Chang, Natascha Ching, Len Tanaka, Marian E. Melish, Prashant Purohit
Publikováno v:
Critical Care Medicine. 49:388-388
Autor:
Shujun Yuan, Derek Sim, Perry Liu, Peter Bringmann, Martin Rosenbruch, Katalin Kauser, Keith Abe, Jian-Ming Gu
Publikováno v:
Experimental hematology. 60
Vaso-occlusive crisis (VOC) is the most common and debilitating complication of sickle cell disease (SCD); recurrent episodes cause organ damage and contribute to early mortality. Plasma placental growth factor (PlGF) levels are elevated in SCD and c
Autor:
Malia, Rasa, James, Musgrave, Keith, Abe, Len, Tanaka, Konstantine, Xoinis, Bruce, Shiramizu, Gretchen, Foskett, Rhiana, Lau
Publikováno v:
Journal of Investigative Medicine High Impact Case Reports
Hemolytic uremic syndrome (HUS) can be classified as typical and atypical, and the treatment recommendations currently differ between the 2 types. Eculizumab is recommended as first-line treatment for atypical HUS; however, its use in typical HUS has
Autor:
Andrew M. Scharenberg, Laura Smith, Chester Jacobs, Karen Vo, Chandra Patel, Keith Abe, David J. Rawlings, West Samuel, Gene Uenishi, Troy R. Torgerson, Simon Gebremeskel, Cade E. Ito, Cornell Mallari, Greg Boucher, Karen Sommer, Samantha Chin, Luis Gamboa, Dariusz Wodziak, Basha Stankovich, Noelle Dahl, Rangoli Aeran, Greg J. Cost
Publikováno v:
Blood. 134:3355-3355
Regulatory T-cells (Treg) depend on signals from IL2 and their endogenous T-cell receptors to survive, proliferate, and maintain suppressive activity. We have developed a strategy for engineering effector CD4 T-cells into edited, regulatory-like T-ce
Autor:
Cornell Mallari, Andrew M. Scharenberg, Gregory J. Cost, Bee-Chun Sun, Gene Uenishi, Keith Abe
Publikováno v:
Blood. 132:3480-3480
The ability to edit the genome of long-term-engrafting hematopoietic stem cells (LT-HSCs) would provide a curative therapy for a wide range of hematological disorders. While mixed LT/ST-HSC (ST, short-term) pools edited via non-homologous end joining
Autor:
Andrew M. Scharenberg, Sowndharya Rajavel, Cade E. Ito, Gregory J. Cost, Gene Uenishi, Keith Abe, Valerie Guerrero
Publikováno v:
Blood. 132:2203-2203
Auto-reactive antibody production by plasma cells is the direct cause of many auto-immune diseases. In such cases elimination of plasma cells would ameliorate the disease. Chimeric antigen receptor T (CAR-T) cells with cytotoxicity toward cells expre
Autor:
Peter I. Teng, Thomas Quertermous, Keith Abe, László G. Kömüves, James N. Topper, Maria R. Dichiara
Publikováno v:
Physiological Genomics. 11:99-107
We have developed a system utilizing the murine Tie2 promoter/enhancer coupled with the "tetracycline-on" regulatory elements to create a model that allows regulated and selective expression of a beta-galactosidase (betaGal) reporter transgene in the