Zobrazeno 1 - 10
of 195
pro vyhledávání: '"Keitaro Yamanouchi"'
Autor:
Keitaro YAMANOUCHI, Shizuka KATO, Yukie TANAKA, Masanari IKEDA, Yukina OSHIMO, Takanori SHIGA, Kei HATAMOTO, James CHAMBERS, Takuya IMAMURA, Ryuji HIRAMATSU, Kazuyuki UCHIDA, Fuko MATSUDA, Takashi MATSUWAKI, Tetsuya KOHSAKA
Publikováno v:
The Journal of Reproduction and Development, Vol 70, Iss 2, Pp 55-64 (2024)
The mammalian X chromosome exhibits enrichment in genes associated with germ cell development. Previously, we generated a rat model of Becker muscular dystrophy (BMD) characterized by an in-frame mutation in the dystrophin gene, situated on the X chr
Externí odkaz:
https://doaj.org/article/ecc08a81b4cf491cb44a10573b2b3d4f
Autor:
Yuki Kihara, Yukie Tanaka, Masanari Ikeda, Jun Homma, Ryo Takagi, Keiko Ishigaki, Keitaro Yamanouchi, Hiroaki Honda, Satoru Nagata, Masayuki Yamato
Publikováno v:
Regenerative Therapy, Vol 21, Iss , Pp 486-493 (2022)
Introduction: Duchenne muscular dystrophy (DMD) is a progressive disease that leads to damage of muscle and myocardium due to genetic abnormalities in the dystrophin gene. In utero cell transplantation that might facilitate allogenic transplantation
Externí odkaz:
https://doaj.org/article/ba8eb31e37f24328b7308889df383856
Autor:
Keitaro Yamanouchi, Yukie Tanaka, Masanari Ikeda, Shizuka Kato, Ryosuke Okino, Hiroki Nishi, Fumihiko Hakuno, Shin-Ichiro Takahashi, James Chambers, Takashi Matsuwaki, Kazuyuki Uchida
Publikováno v:
Skeletal Muscle, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Background Duchenne muscular dystrophy (DMD) is an X-linked muscle disease caused by a complete lack of dystrophin, which stabilizes the plasma membrane of myofibers. The orofacial function is affected in an advanced stage of DMD and this of
Externí odkaz:
https://doaj.org/article/aeae3a048a30439680dbbe41dd4509b4
Autor:
Yuri Fujikura, Koichi Kimura, Keitaro Yamanouchi, Hidetoshi Sugihara, Masaki Hatakeyama, Haotong Zhuang, Tomoki Abe, Masao Daimon, Hiroyuki Morita, Issei Komuro, Katsutaka Oishi
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Duchenne muscular dystrophy (DMD) is an X-linked recessive myopathy caused by dystrophin mutations. Although respiratory management has improved the prognosis of patients with DMD, inevitable progressive cardiomyopathy is a current leading c
Externí odkaz:
https://doaj.org/article/d50f2bb6f4b9403ab67d58c916cd780c
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Duchenne muscular dystrophy (DMD) is an X-linked fatal muscular disease, affecting one in 3,500 live male births worldwide. Currently, there is no cure for this disease, except for steroid-based treatment to attenuate disease progression. Cell transp
Externí odkaz:
https://doaj.org/article/19836df5eb434a1a9f257bb3af7bb5a7
Autor:
Yuri Fujikura, Keitaro Yamanouchi, Hidetoshi Sugihara, Masaki Hatakeyama, Tomoki Abe, Satoru Ato, Katsutaka Oishi
Publikováno v:
Biochemistry and Biophysics Reports, Vol 32, Iss , Pp 101378- (2022)
Duchenne muscular dystrophy (DMD) is a myopathy characterized by progressive muscle weakness caused by a mutation in the dystrophin gene on the X chromosome. We recently showed that a medium-chain triglyceride-containing ketogenic diet (MCTKD) improv
Externí odkaz:
https://doaj.org/article/5d6a200037814dee9ec1d7237174ad5c
Autor:
Naomi Teramoto, Hidetoshi Sugihara, Keitaro Yamanouchi, Katsuyuki Nakamura, Koichi Kimura, Tomoko Okano, Takanori Shiga, Taku Shirakawa, Masafumi Matsuo, Tetsuya Nagata, Masao Daimon, Takashi Matsuwaki, Masugi Nishihara
Publikováno v:
Disease Models & Mechanisms, Vol 13, Iss 9 (2020)
Dystrophin, encoded by the DMD gene on the X chromosome, stabilizes the sarcolemma by linking the actin cytoskeleton with the dystrophin-glycoprotein complex (DGC). In-frame mutations in DMD cause a milder form of X-linked muscular dystrophy, called
Externí odkaz:
https://doaj.org/article/a399ff435644417caf8d668df3203c5b
Publikováno v:
Journal of Animal Reproduction and Biotechnology, Vol 29, Iss 3, Pp 235-240 (2014)
Ethylene glycol (EG) has been successfully used as a cryoprotectant for vitrification of mammalian embryos (including human embryos) due to its low formula weight and high permeation into cells compared with other cryoprotectants, including propylene
Externí odkaz:
https://doaj.org/article/c5a4e57c1d7347bca4c6d0a50c14c3d1
Publikováno v:
Journal of Animal Reproduction and Biotechnology, Vol 29, Iss 3, Pp 241-248 (2014)
This study was carried out to evaluate the effects of embryonic stage, cryoprotectant, and freezing-thawing method on the rates of survival and development of the cryopreserved mouse early embryo and finally to establish the cryopreservation method o
Externí odkaz:
https://doaj.org/article/60e040f81d7a4bc2bc077ba7b25b5c37
Autor:
Fumihiko Hakuno, Yoko Yamauchi, Gen Kaneko, Yosuke Yoneyama, Jun Nakae, Kazuhiro Chida, Tatsuhiko Kadowaki, Keitaro Yamanouchi, Masugi Nishihara, Shin-Ichiro Takahashi
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e25655 (2011)
Insulin-like growth factors (IGFs) are well known to play essential roles in enhancement of myogenic differentiation. In this report we showed that initial IGF-I signal activation but long-term IGF-1 signal termination are required for myogenic diffe
Externí odkaz:
https://doaj.org/article/2cee6e660c0f41748b202c6c0def952f