Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Keita Uchida"'
Publikováno v:
Physiological Reports, Vol 11, Iss 15, Pp n/a-n/a (2023)
Abstract Remodeling of cardiac t‐tubules in normal and pathophysiological conditions is an important process contributing to the functional performance of the heart. While it is well documented that deterioration of t‐tubule network associated wi
Externí odkaz:
https://doaj.org/article/204cad51122b4591822efc7fcbe8c5c8
Autor:
Emily A. Scarborough, Keita Uchida, Maria Vogel, Noa Erlitzki, Meghana Iyer, Sai Aung Phyo, Alexey Bogush, Izhak Kehat, Benjamin L. Prosser
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
New contractile units are required during cardiac hypertrophy, though it remains unclear precisely where and how these new sarcomeres are added. Here the authors reveal that in the heart, microtubules spatiotemporally regulate mRNAs and ribosomes to
Externí odkaz:
https://doaj.org/article/45f029fcfdd34855a349043120951555
Autor:
Sai Aung Phyo, Keita Uchida, Christina Yingxian Chen, Matthew A. Caporizzo, Kenneth Bedi, Joanna Griffin, Kenneth Margulies, Benjamin L. Prosser
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
A proliferated and post-translationally modified microtubule network underlies cellular growth in cardiac hypertrophy and contributes to contractile dysfunction in heart failure. Yet how the heart achieves this modified network is poorly understood.
Externí odkaz:
https://doaj.org/article/cb8fb63a82a94d1f96a0aa4051e2f54b
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Efficient excitation-contraction coupling in ventricular myocytes depends critically on the presence of the t-tubular network. It has been recently demonstrated that cholesterol, a major component of the lipid bilayer, plays an important role in long
Externí odkaz:
https://doaj.org/article/b7f4c625633e42498a9a5b12608d88be
Autor:
Sarah N Cilvik, Joy I Wang, Kory J Lavine, Keita Uchida, Angela Castro, Carolyn M Gierasch, Carla J Weinheimer, Stacey L House, Attila Kovacs, Colin G Nichols, David M Ornitz
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e82979 (2013)
Fibroblast growth factors (FGFs) and their receptors are highly conserved signaling molecules that have been implicated in postnatal cardiac remodeling. However, it is not known whether cardiomyocyte-expressed FGF receptors are necessary or sufficien
Externí odkaz:
https://doaj.org/article/e3c86d1f5cca41bf88dba6cd2bbbd09f
Autor:
Marco Luciani, Mauro Montalbano, Luca Troncone, Camilla Bacchin, Keita Uchida, Gianlorenzo Daniele, Bethany Jacobs Wolf, Helen M Butler, Justin Kiel, Stefano Berto, Cortney Gensemer, Kelsey Moore, Jordan Morningstar, Thamonwan Diteepeng, Onder Albayram, José F Abisambra, Russell A Norris, Thomas G Di Salvo, Benjamin Prosser, Rakez Kayed, Federica del Monte
Publikováno v:
European Heart Journal. 44:1560-1570
Background Amyloid plaques and neurofibrillary tangles, the molecular lesions that characterize Alzheimer’s disease (AD) and other forms of dementia, are emerging as determinants of proteinopathies ‘beyond the brain’. This study aims to establi
Autor:
Vasiliki Courelli, Keita Uchida, Alexia Vite, Benjamin Prosser, Kenneth Margulies, Michael Ibrahim
Publikováno v:
Journal of Molecular and Cellular Cardiology. 173:138-139
Publikováno v:
Journal of Molecular and Cellular Cardiology. 173:17-18
Publikováno v:
Am J Physiol Heart Circ Physiol
Cardiac t tubules undergo significant remodeling in various pathological and experimental conditions, which can be associated with mechanical or osmotic stress. In particular, it has been shown that removal of hyposmotic stress can lead to sealing of
Publikováno v:
Journal of the Japan Institute of Metals and Materials. 84:58-65