Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Keita Tomioka"'
Autor:
Keita Tomioka, Tatsuo Miyamoto, Silvia Natsuko Akutsu, Hiromi Yanagihara, Kazumasa Fujita, Ekaterina Royba, Hiroshi Tauchi, Takashi Yamamoto, Iemasa Koh, Eiji Hirata, Yoshiki Kudo, Masao Kobayashi, Satoshi Okada, Shinya Matsuura
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Genetic information is protected against a variety of genotoxins including ionizing radiation (IR) through the DNA double-strand break (DSB) repair machinery. Genome-wide association studies and clinical sequencing of cancer patients have su
Externí odkaz:
https://doaj.org/article/48c6efd18e614b7e83decd8058014ba6
Autor:
Silvia Natsuko Akutsu, Tatsuo Miyamoto, Daiju Oba, Keita Tomioka, Hiroshi Ochiai, Hirofumi Ohashi, Shinya Matsuura
Publikováno v:
PLoS ONE, Vol 17, Iss 3 (2022)
Trisomy 21, 18, and 13 are the major autosomal aneuploidy disorders in humans. They are mostly derived from chromosome non-disjunction in maternal meiosis, and the extra trisomic chromosome can cause several congenital malformations. Various genes on
Externí odkaz:
https://doaj.org/article/b0fd28459f2949acb6093b25fb737922
Publikováno v:
Cells, Vol 9, Iss 1, p 239 (2020)
Chromosomal segregation errors in germ cells and early embryonic development underlie aneuploidies, which are numerical chromosomal abnormalities causing fetal absorption, developmental anomalies, and carcinogenesis. It has been considered that human
Externí odkaz:
https://doaj.org/article/505a3ce0c65b47d29a74ec0ee955f9f9
Autor:
Risa Matsumura, Hiroshi Kawaguchi, Shiho Nishimura, Yoko Mizoguchi, Masao Kobayashi, Keita Tomioka
Publikováno v:
Blood. 134:1127-1127
Prophylactic administration of factor VIII products is necessary to prevent bleeding and preserve normal musculoskeletal function in children with severe hemophilia A (HA). Recently, extended half-life recombinant factor VIII (EHL-rFVIII) products ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ab6b0469c163c8b5068712dc397c956
https://doi.org/10.1182/blood-2019-128149
https://doi.org/10.1182/blood-2019-128149
Autor:
Masao Kobayashi, Yuko Nakashima, Keita Tomioka, Maiko Shimomura, Shinobu Sasaki, Yoshiko Matsubara, Nobuo Adachi, Yoko Mizoguchi, Kazuo Awai, Shiho Nishimura, Chihiro Tani
Publikováno v:
Blood. 132:5027-5027
The regular prophylactic replacement therapy with clotting factors has significantly reduced the arthropathy in patients with hemophilia. Early detection of the signs of joint damage is important to prevent the progressive joint damage. For the early
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa019627f181fcbe73e14de42dbff3df
https://doi.org/10.1182/blood-2018-99-120016
https://doi.org/10.1182/blood-2018-99-120016
Autor:
Atsushi Ono, Nakao Konishi, Hiroshi Kawaguchi, Ikue Chijimatsu, Aya Furue, Masao Kobayashi, Yusuke Imanaka, Keita Tomioka, Mizuka Miki, Reiko Kagawa, Shiho Nishimura, Satoshi Saito, Maiko Shimomura, Yoko Mizoguchi
Publikováno v:
International journal of hematology. 103(4)
The production of factor VIII (FVIII) inhibitory antibodies is a serious problem in patients with hemophilia A. Immune tolerance induction (ITI) is the only strategy proven to eradicate persistent inhibitors and has been shown to be successful in 70
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f0e4f1d3dc6ff446344fb3809b7d34e
https://pubmed.ncbi.nlm.nih.gov/26830966
https://pubmed.ncbi.nlm.nih.gov/26830966
Autor:
Keita Tomioka, Aya Furue, Maiko Shimomura, Masao Kobayashi, Kazuhiro Nakamura, Shuhei Karakawa, Hiroshi Kawaguchi, Sonoko Sakata, Ikue Chijimatsu, Mizuka Miki, Shiho Nishimura, Takehiko Doi, Satoshi Okada, Yoko Mizoguchi
Publikováno v:
Blood. 128:3688-3688
Severe congenital neutropenia (SCN) is a rare heterogeneous genetic disorder characterized by severe chronic neutropenia, with absolute neutrophil counts below 0.5×109/L, and by recurrent bacterial infections from early infancy. Granulocyte colony-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0531522bd39ecb922588622ee45c482
https://doi.org/10.1182/blood.v128.22.3688.3688
https://doi.org/10.1182/blood.v128.22.3688.3688
Autor:
Masao Kobayashi, Yoko Mizoguchi, Mizuka Miki, Shiho Nishimura, Hiroshi Kawaguchi, Kazuhiro Nakamura, Keita Tomioka, Shuhei Karakawa
Publikováno v:
Blood. 124:5920-5920
Severe congenital neutropenia (SCN) is characterized by severe chronic neutropenia with a absolute neutrophil count of less than 0.5×109/L, maturation arrest of myeloid precursors at the promyelocyts/myelocyte stage, and the recurrent bacterial infe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ce1b4c8b87fef31b889b55f74ea83f0
https://doi.org/10.1182/blood.v124.21.5920.5920
https://doi.org/10.1182/blood.v124.21.5920.5920