Zobrazeno 1 - 10
of 184
pro vyhledávání: '"Keita Saku"'
Autor:
Hiroki Matsushita, Keita Saku, Takuya Nishikawa, Shohei Yokota, Kei Sato, Hidetaka Morita, Yuki Yoshida, Masafumi Fukumitsu, Kazunori Uemura, Toru Kawada, Ken Yamaura
Publikováno v:
Intensive Care Medicine Experimental, Vol 12, Iss 1, Pp 1-15 (2024)
Abstract Background ECPELLA, a combination of veno-arterial (VA) extracorporeal membrane oxygenation (ECMO) and Impella, a percutaneous left ventricular (LV) assist device, has emerged as a novel therapeutic option in patients with severe cardiogenic
Externí odkaz:
https://doaj.org/article/912f96fc2e8b45778aebf069fd5611a9
Publikováno v:
Journal of Intensive Care, Vol 11, Iss 1, Pp 1-14 (2023)
Abstract Cardiogenic shock is a complex and diverse pathological condition characterized by reduced myocardial contractility. The goal of treatment of cardiogenic shock is to improve abnormal hemodynamics and maintain adequate tissue perfusion in org
Externí odkaz:
https://doaj.org/article/85a62b42d4134f6eb5c5e5bd22434519
Autor:
Kazumasu Sasaki, Toru Kawada, Hiroki Matsushita, Shohei Yokota, Midori Kakuuchi, Aimi Yokoi, Yuki Yoshida, Hidetaka Morita, Kei Sato, Takuya Nishikawa, Annette P. N. Kutter, Yasuyuki Kataoka, Joe Alexander, Keita Saku, Tatsuya Ishikawa, Kazunori Uemura
Publikováno v:
Frontiers in Veterinary Science, Vol 11 (2024)
IntroductionIntra-operative hypotension is a common complication of surgery under general anesthesia in dogs and humans. Computer-controlled closed-loop infusion systems of norepinephrine (NE) have been developed and clinically applied for automated
Externí odkaz:
https://doaj.org/article/37db7acad19043b580ca2e3966debd9e
Autor:
Toru Kawada, Meihua Li, Akitsugu Nishiura, Yuki Yoshida, Shohei Yokota, Hiroki Matsushita, Masafumi Fukumitsu, Kazunori Uemura, Joe Alexander, Keita Saku
Publikováno v:
Journal of Physiological Sciences, Vol 73, Iss 1, Pp 1-12 (2023)
Abstract Sodium–glucose cotransporter 2 (SGLT2) inhibitors have exerted cardioprotective effects in clinical trials, but underlying mechanisms are not fully understood. As mitigating sympathetic overactivity is of major clinical concern in the mech
Externí odkaz:
https://doaj.org/article/e40a9c4bd9954cdfa2d9900b9322166b
Autor:
Toru Kawada, Hiromi Yamamoto, Aimi Yokoi, Akitsugu Nishiura, Midori Kakuuchi, Shohei Yokota, Hiroki Matsushita, Joe Alexander, Keita Saku
Publikováno v:
Journal of Physiological Sciences, Vol 73, Iss 1, Pp 1-12 (2023)
Abstract Although suppression of sympathetic activity is suggested as one of the underlying mechanisms for the cardioprotective effects afforded by sodium–glucose cotransporter 2 (SGLT2) inhibitors, whether the modulation of glucose handling acutel
Externí odkaz:
https://doaj.org/article/a0a4113fcfb24f429872f1824ed0f85e
Publikováno v:
Pulmonary Circulation, Vol 12, Iss 4, Pp n/a-n/a (2022)
Abstract Vagal nerve stimulation (VNS) ameliorates pulmonary vascular remodeling and improves survival in a rat model of pulmonary hypertension (PH). However, the direct impact of VNS on right ventricular (RV) function, which is the key predictor of
Externí odkaz:
https://doaj.org/article/626d9b226cb14e2fa9207b9c02a9a328
Publikováno v:
Physiological Reports, Vol 10, Iss 14, Pp n/a-n/a (2022)
Abstract Since the arterial baroreflex system is classified as an immediate control system, the focus has been on analyzing its dynamic characteristics in the frequency range between 0.01 and 1 Hz. Although the dynamic characteristics in the frequenc
Externí odkaz:
https://doaj.org/article/4e17153480764785b89de65c0052dc1d
Autor:
Tadayoshi Miyamoto, Daisuke Sotobayashi, Go Ito, Eriko Kawai, Hidehiro Nakahara, Shinya Ueda, Takeshi Toyama, Keita Saku, Yasuto Nakanishi, Hiroshi Kinoshita
Publikováno v:
Physiological Reports, Vol 10, Iss 5, Pp n/a-n/a (2022)
Abstract This study aimed to investigate whether anticipatory cardiorespiratory responses vary depending on the intensity of the subsequent exercise bout, and whether anticipatory cardiorespiratory adjustments contribute importantly to enhancing exer
Externí odkaz:
https://doaj.org/article/b82947e4624d4730aa31ecbc7fe07158
Autor:
Takuya Nishikawa, Keita Saku, Kiyoshi Uike, Kazunori Uemura, Genya Sunagawa, Takeshi Tohyama, Keimei Yoshida, Takuya Kishi, Kenji Sunagawa, Hiroyuki Tsutsui
Publikováno v:
ESC Heart Failure, Vol 7, Iss 5, Pp 3075-3085 (2020)
Abstract Aims Interatrial shunting (IAS) reduces left atrial pressure in patients with heart failure. Several clinical trials reported that IAS improved the New York Heart Association score and exercise capacity. However, its effects on haemodynamics
Externí odkaz:
https://doaj.org/article/5b71593c165d4464b1800265e2b3d258
Autor:
Toru Kawada, Hiromi Yamamoto, Tadayoshi Miyamoto, Yohsuke Hayama, Meihua Li, Can Zheng, Kazunori Uemura, Masaru Sugimachi, Keita Saku
Publikováno v:
Physiological Reports, Vol 9, Iss 23, Pp n/a-n/a (2021)
Abstract Muscarinic potassium channels (IK,ACh) are thought to contribute to the high frequency (HF) dynamic heart rate (HR) response to vagal nerve stimulation (VNS) because they act faster than the pathway mediated by hyperpolarization‐activated
Externí odkaz:
https://doaj.org/article/bf636843e8f3451297e267606343cc94