Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Keita Saeki"'
Publikováno v:
Food & Nutrition Research, Vol 66, Pp 1-10 (2022)
Background: A mixture of five herbal extracts called internatural (INT), which is prepared from pumpkin seeds, purple turmeric, pearl barley, corn pistil, and cinnamon, is widely used by people in Japan and elsewhere for its immunity-enhancing effect
Externí odkaz:
https://doaj.org/article/24f249e327684d04a429a4252cb5a83e
Autor:
Takashi Sekiya, Sana Hibino, Keita Saeki, Mitsuhiro Kanamori, Satoshi Takaki, Akihiko Yoshimura
Publikováno v:
Cell Reports, Vol 24, Iss 6, Pp 1627-1638.e6 (2018)
Summary: Regulatory T (Treg) cells develop from a self-reactive, CD4-single positive (CD4SP) precursor cell pool. Thus, Treg-fated developing thymocytes are expected to possess the potential to generate pathogenic self-reactive cells. However, no suc
Externí odkaz:
https://doaj.org/article/66a305dfc10540d8a353519d34058c55
Autor:
Yoshinori Ohno, Shin'ichiro Yasunaga, Salima Janmohamed, Motoaki Ohtsubo, Keita Saeki, Toshiaki Kurogi, Keichiro Mihara, Norman N Iscove, Yoshihiro Takihara
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53161 (2013)
Hoxb4, a 3'-located Hox gene, enhances hematopoietic stem cell (HSC) activity, while a subset of 5'-located Hox genes is involved in hematopoiesis and leukemogenesis, and some of them are common translocation partners for Nucleoporin 98 (Nup98) in pa
Externí odkaz:
https://doaj.org/article/634246b9d6a346179ece6d459995ed46
Autor:
Satoshi Kubo, Rhea Kataria, Yikun Yao, Justin Q. Gabrielski, Lixin Zheng, Tovah E. Markowitz, Waipan Chan, Jian Song, Arun K. Boddapati, Keita Saeki, Björn Häupl, Ann Y. Park, Yan H. Cheng, Jing Cui, Thomas Oellerich, Michael J. Lenardo
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(33)
Apoptosis is a genetically regulated program of cell death that plays a key role in immune disease processes. We identified EBF4, a little-studied member of the early B cell factor (EBF) family of transcription factors, in a whole-genome CRISPR scree
Autor:
Daisuke Kurotaki, Kenta Kikuchi, Kairong Cui, Wataru Kawase, Keita Saeki, Junpei Fukumoto, Akira Nishiyama, Kisaburo Nagamune, Keji Zhao, Keiko Ozato, Pedro P. Rocha, Tomohiko Tamura
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Classical dendritic cells (cDCs) are essential for immune responses and differentiate from hematopoietic stem cells via intermediate progenitors, such as monocyte−DC progenitors (MDPs) and common DC progenitors (CDPs). Upon infection, cDCs are acti
Autor:
Mitsuhiro Kanamori, Takashi Sekiya, Keita Saeki, Akihiko Yoshimura, Satoshi Takaki, Sana Hibino
Publikováno v:
Cell Reports, Vol 24, Iss 6, Pp 1627-1638.e6 (2018)
Summary: Regulatory T (Treg) cells develop from a self-reactive, CD4-single positive (CD4SP) precursor cell pool. Thus, Treg-fated developing thymocytes are expected to possess the potential to generate pathogenic self-reactive cells. However, no suc
Autor:
Hajime Higuchi, Hiromitsu Soma, Yoshiyuki Yamagishi, Takanori Kanai, Naohisa Yahagi, Shigenari Hozawa, Keita Saeki, Kaori Kameyama, Yuji Nakamura, Naoteru Miyata, Yohei Masugi
Publikováno v:
Gut and Liver
We report herein improved methods for the safe and successful completion of endoscopic papillectomy (EP). Between January 2008 and November 2011, 12 patients underwent double-snare retracting papillectomy for the treatment of lesions of the major duo
Autor:
Toshiaki Kurogi, Kyoko Suzuki-Takedachi, Yoshihiro Takihara, Yoshinori Ohno, Motoaki Ohtsubo, Kenichi Yoshida, Keita Saeki, Manabu Shirai, Shin'ichiro Yasunaga, J. Willem Voncken, Keichiro Mihara
Publikováno v:
Molecular Biology of the Cell
Molecular Biology of the Cell, 25(8), 1374-1383. American Society for Cell Biology
Molecular Biology of the Cell, 25(8), 1374-1383. American Society for Cell Biology
Geminin transcription, regulated by E2Fs, is negatively regulated by Geminin through the inhibition of chromatin remodeling. Geminin transcription is thus regulated by a negative-feedback loop through the chromatin configuration. Homeostatically regu
Autor:
Toshifumi Hibi, Junichiro Irie, Toshiaki Teratani, Shigenari Hozawa, Keita Saeki, Tadakazu Hisamatsu, Hirotoshi Ebinuma, Yohei Mikami, Takahiro Suzuki, Jun Miyoshi, Nobuhiro Nakamoto, Yoshiyuki Yamagishi, Miho Takabe, Hiroshi Itoh, Yuji Nakamura, Naoteru Miyata, Hajime Higuchi, Takanori Kanai, Hidetsugu Saito
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 304:G700-G707
Glucagon-like peptide-1 (GLP-1) promotes insulin release; however, the relationship between the GLP-1 signal and chronic pancreatitis is not well understood. Here we focus on chemokine (C-C motif) ligand 2 (CCL2) and its receptor (CCR2) axis, which r
Autor:
Toru Igarashi, Hajime Higuchi, Toshifumi Hibi, Akiko Yokoyama, Toshifumi Azuma, Naoteru Miyata, Shigenari Hozawa, Keita Saeki, Ayano Kabashima
Publikováno v:
Pancreas. 41:745-752
OBJECTIVES The objectives of the present study were (i) to identify a novel tumor suppressor gene whose expression level was regulated by transforming growth factor (TGF-β) and (ii) to evaluate the effect of Ras/MEK/ERK signaling on TGF-β-dependent