Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Keita Kohno"'
Autor:
Chinatsu Shinozaki, Keita Kohno, Mitsunori Shiroishi, Daisuke Takahashi, Yu Yoshikawa, Yoshito Abe, Kenji Hamase, Makoto Nakakido, Kohei Tsumoto, Kazuhide Inoue, Makoto Tsuda, Tadashi Ueda
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract We have recently developed a mouse monoclonal antibody (12–10H) binding to the head domain region in rat P2X4 receptor (rP2X4R, which is crucial for the pathogenesis of neuropathic pain) expressed on the cell with the highest binding affin
Externí odkaz:
https://doaj.org/article/56486021f0394e62b51df59f5de03618
Autor:
Keita Kohno, Makoto Tsuda
Publikováno v:
PAIN Reports, Vol 6, Iss 1, p e864 (2021)
Abstract. Pain plays an indispensable role as an alarm system to protect us from dangers or injuries. However, neuropathic pain, a debilitating pain condition caused by damage to the nervous system, persists for a long period even in the absence of d
Externí odkaz:
https://doaj.org/article/184453fb17f149cb97de520f7ac2114c
Autor:
Tomohiro Yamashita, Shota Yamamoto, Jiaming Zhang, Miho Kometani, Daisuke Tomiyama, Keita Kohno, Hidetoshi Tozaki-Saitoh, Kazuhide Inoue, Makoto Tsuda
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0165189 (2016)
P2X4 receptors (P2X4R) are a family of ATP-gated non-selective cation channels. We previously demonstrated that activation of P2X4R in spinal microglia is crucial for neuropathic pain, a highly debilitating chronic pain condition, suggesting that P2X
Externí odkaz:
https://doaj.org/article/2640ccb4e24042e29f531abd924b51c7
Autor:
Keita Kohno1,2, Ryoji Shirasaka3, Kohei Yoshihara3, Satsuki Mikuriya1, Kaori Tanaka4, Keiko Takanami5,6, Kazuhide Inoue7, Hirotaka Sakamoto5, Yasuyuki Ohkawa4, Takahiro Masuda1,2, Makoto Tsuda1,2 tsuda@phar.kyushu-u.ac.jp
Publikováno v:
Science. 4/1/2022, Vol. 376 Issue 6588, p86-90. 5p. 4 Diagrams.
Publikováno v:
Trends in Neurosciences.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c26b7247687af07fbf682f3f145c8732
https://doi.org/10.1016/j.tins.2023.05.001
https://doi.org/10.1016/j.tins.2023.05.001
Autor:
Makoto Tsuda, Keita Kohno
Publikováno v:
Folia Pharmacologica Japonica; 2023, Vol. 158 Issue 5, p362-366, 5p
Autor:
Miho Shiratori-Hayashi, Motohiro Nishida, Kazuhide Inoue, Kazushi Eguchi, Makoto Tsuda, Yuto Shiraishi, Katsuhiko Mikoshiba, Keita Kohno, Chiharu Yamaguchi
Publikováno v:
Journal of Allergy and Clinical Immunology. 147:1341-1353
Background Chronic itch is a debilitating symptom of inflammatory skin diseases, but the underlying mechanism is poorly understood. We have recently demonstrated that astrocytes in the spinal dorsal horn become reactive in models of atopic and contac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f21fd1ac75242cc433d6482aa0fa57c
https://doi.org/10.1016/j.jaci.2020.06.039
https://doi.org/10.1016/j.jaci.2020.06.039
Autor:
Teruaki Ono, Hidetoshi Tozaki-Saitoh, Yasuharu Nakashima, Makoto Tsuda, Keita Kohno, Yuta Kohro
Publikováno v:
Brain, Behavior, and Immunity. 89:389-399
Chronic pain is one of the main symptoms of spinal disorders such as spinal canal stenosis. A major cause of this pain is related to compression of the spinal cord, and chronic pain can develop at the level of the compressed spinal segment. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e9334b3eef8b6df49299c8ebda15db2
https://doi.org/10.1016/j.bbi.2020.07.025
https://doi.org/10.1016/j.bbi.2020.07.025
Autor:
Po Sung Chu, Masayuki Inoue, Yuya Hagihara, Takaharu Okada, Akihiko Yoshimura, Mamoru Tanida, Yosuke Harada, Harumichi Ishigame, Minoru Matsui, Toshihiko Yada, Yusaku Iwasaki, Kentaro Miyamoto, Hideyuki Okano, Takanori Kanai, Wataru Suda, Nobuhito Taniki, Shinsuke Shibata, Nobuhiro Nakamoto, Yuko Kitagawa, Yohei Mikami, Masahira Hattori, Toshiaki Teratani, Tomohisa Sujino, Keita Kohno, Takahiro Suzuki, Koji Okabayashi, Makoto Tsuda
Publikováno v:
Nature. 585:591-596
Recent clinical and experimental evidence has evoked the concept of the gut–brain axis to explain mutual interactions between the central nervous system and gut microbiota that are closely associated with the bidirectional effects of inflammatory b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43acf5e446c02266792cb6af72e7608d
https://doi.org/10.1038/s41586-020-2425-3
https://doi.org/10.1038/s41586-020-2425-3
Autor:
Miho, Shiratori-Hayashi, Chiharu, Yamaguchi, Kazushi, Eguchi, Yuto, Shiraishi, Keita, Kohno, Katsuhiko, Mikoshiba, Kazuhide, Inoue, Motohiro, Nishida, Makoto, Tsuda
Publikováno v:
The Journal of allergy and clinical immunology. 147(4)
Chronic itch is a debilitating symptom of inflammatory skin diseases, but the underlying mechanism is poorly understood. We have recently demonstrated that astrocytes in the spinal dorsal horn become reactive in models of atopic and contact dermatiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f450f3dfa22e16bcb3f17fb6e7b0d5ed
https://pubmed.ncbi.nlm.nih.gov/32781002
https://pubmed.ncbi.nlm.nih.gov/32781002