Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Keita Hiraga"'
Autor:
Keita Hiraga, Makoto Hattori, Yuki Satake, Daigo Tamakoshi, Taiki Fukushima, Takashi Uematsu, Takashi Tsuboi, Maki Sato, Katsunori Yokoi, Keisuke Suzuki, Yutaka Arahata, Yukihiko Washimi, Akihiro Hori, Masayuki Yamamoto, Hideaki Shimizu, Masakazu Wakai, Harutsugu Tatebe, Takahiko Tokuda, Akinori Nakamura, Shumpei Niida, Masahisa Katsuno
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-11 (2024)
Abstract Comorbid Alzheimer’s disease (AD) neuropathology is common in Lewy body disease (LBD); however, AD comorbidity in the prodromal phase of LBD remains unclear. This study investigated AD comorbidity in the prodromal and symptomatic phases of
Externí odkaz:
https://doaj.org/article/6c580b4813af4d3f98397e9dbd06a241
Autor:
Makoto Hattori, Keita Hiraga, Yuki Satake, Takashi Tsuboi, Daigo Tamakoshi, Maki Sato, Katsunori Yokoi, Keisuke Suzuki, Yutaka Arahata, Akihiro Hori, Motoshi Kawashima, Hideaki Shimizu, Hiroshi Matsuda, Katsuhiko Kato, Yukihiko Washimi, Masahisa Katsuno
Publikováno v:
npj Parkinson's Disease, Vol 9, Iss 1, Pp 1-9 (2023)
Abstract Individuals with prodromal symptoms of Lewy body disease (LBD), such as rapid eye movement sleep behavior disorder (RBD), often showed imaging defects similar to patients with Parkinson’s disease and dementia with Lewy bodies. We examined
Externí odkaz:
https://doaj.org/article/8e2fea013a514829a4b3af0fa64418dd
Autor:
Takashi Tsuboi, Yuki Satake, Keita Hiraga, Katsunori Yokoi, Makoto Hattori, Masashi Suzuki, Kazuhiro Hara, Adolfo Ramirez-Zamora, Michael S. Okun, Masahisa Katsuno
Publikováno v:
npj Parkinson's Disease, Vol 8, Iss 1, Pp 1-21 (2022)
Abstract Non-motor symptoms (NMS) are common among patients with Parkinson’s disease and reduce patients’ quality of life (QOL). However, there remain considerable unmet needs for NMS management. Three monoamine oxidase B inhibitors (MAO-BIs), se
Externí odkaz:
https://doaj.org/article/4b591779a84141ea87740810762727f7
Autor:
Tracy T. Chuong, Toshihiko Ogura, Norihito Hiyoshi, Kazuma Takahashi, Sangho Lee, Keita Hiraga, Hiroki Iwase, Akira Yamaguchi, Kiyoto Kamagata, Eriko Mano, Satoshi Hamakawa, Hirotomo Nishihara, Takashi Kyotani, Galen D. Stucky, Tetsuji Itoh
Publikováno v:
ACS Applied Materials & Interfaces. 14:26507-26516
Cryogenic electron microscopy is one of the fastest and most robust methods for capturing high-resolution images of proteins, but stringent sample preparation, imaging conditions, and in situ radiation damage inflicted during data acquisition directl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04154fb9253b70d077f0e1bf3d1c4f67
https://doi.org/10.1021/acsami.2c06318
https://doi.org/10.1021/acsami.2c06318
Autor:
Kazuhiro Hara, Takashi Tsuboi, Yasuhiro Tanaka, Hirohisa Watanabe, Daisuke Nakatsubo, Maki Sato, Katsunori Yokoi, Jun Torii, Gen Sobue, Masahiko Yamamoto, Yuki Satake, Masahisa Katsuno, Keita Hiraga, Satoshi Maesawa, Kazuya Kawabata, Makoto Hattori
Publikováno v:
Parkinsonism & Related Disorders. 93:8-11
Introduction: The impact of deep brain stimulation (DBS) on speech rhythm and its mechanism remains unclear. We investigated speech rhythm characteristics of patients with Parkinson's disease (PD) treated with subthalamic nucleus (STN) DBS to underst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ead2db098b6d073425cb4f594b9a054
https://doi.org/10.1016/j.parkreldis.2021.10.029
https://doi.org/10.1016/j.parkreldis.2021.10.029
Autor:
Masahisa Katsuno, Makoto Hattori, Keita Hiraga, Yuki Satake, Takashi Tsuboi, Maki Sato, Katsunori Yokoi, Keisuke Suzuki, Yutaka Arahata, Akihiro Hori, Motoshi Kawashima, Hideaki Shimizu, Hiroshi Matsuda, Katsuhiko Kato, Yukihiko Washimi
Individuals with prodromal symptoms of Lewy body disease (LBD), such as rapid eye movement sleep behavior disorder (RBD), often showed imaging defects similar to patients. We examined dopamine transporter (DaT) single-photon-emission computed tomogra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3a13c1e1516d38ec2b6f56a15ed5d67
https://doi.org/10.21203/rs.3.rs-1999286/v1
https://doi.org/10.21203/rs.3.rs-1999286/v1
Autor:
Katsunori Yokoi, Yurie Iribe, Norihide Kitaoka, Takashi Tsuboi, Keita Hiraga, Yuki Satake, Makoto Hattori, Yasuhiro Tanaka, Maki Sato, Akihiro Hori, Masahisa Katsuno
Publikováno v:
Parkinsonism & Related Disorders. :105411
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aee1c57821c7cbfc0544f067423be4d8
https://doi.org/10.1016/j.parkreldis.2023.105411
https://doi.org/10.1016/j.parkreldis.2023.105411
Autor:
Yutaro Saito, Hiroyuki Yatabe, Iori Tamura, Yohei Kondo, Ryo Ishida, Tomohiro Seki, Keita Hiraga, Akihiro Eguchi, Yoichi Takakusagi, Keisuke Saito, Nobu Oshima, Hiroshi Ishikita, Kazutoshi Yamamoto, Murali C. Krishna, Shinsuke Sando
Publikováno v:
Science Advances. 8
Dynamic nuclear polarization (DNP) is a cutting-edge technique that markedly enhances the detection sensitivity of molecules using nuclear magnetic resonance (NMR)/magnetic resonance imaging (MRI). This methodology enables real-time imaging of dynami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27400b5bd45d789348c908a53c42189f
https://doi.org/10.1126/sciadv.abj2667
https://doi.org/10.1126/sciadv.abj2667
Autor:
Atsushi Kobayashi, Yuichi Riku, Keita Hiraga, Maya Mimuro, Hiroaki Miyahara, Yasushi Iwasaki, Shota Ito, Mari Yoshida, Tetsuyuki Kitamoto, Akio Akagi, Tetsuo Ando
Publikováno v:
Neuropathology. 39:452-460
Comprehensive analysis is required for the accurate diagnosis of MV2-type sporadic Creutzfeldt-Jakob disease (sCJD) because it shows a wide clinicopathological spectrum. Here, we describe the clinical findings and neuropathologic observations of an a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8010c959edd6c5b4dae770be54b3721a
https://doi.org/10.1111/neup.12595
https://doi.org/10.1111/neup.12595
Autor:
Makoto Suematsu, Kazuhiro Haginoya, Yuki Sugiura, Tomoyasu Noji, Shigeo Kure, Keita Hiraga, Kyoko Yamada, Yuki Ochiai, Fuminori Sugihara, Shigekazu Nagata, Yasuo Uchiyama, Takuo Nishimura, Hidetaka Kosako, Wataru Shoji, Chigure Suzuki, Atsuo Kikuchi, Masahito Ikawa, Hiroshi Ishikita, Yasuko Kobayashi, Katsumori Segawa, Kohei Nishino, Mitsuhiro Matsunaga, Shinya Iwasawa
Publikováno v:
J Clin Invest
ATP11A translocates phosphatidylserine (PtdSer), but not phosphatidylcholine (PtdCho), from the outer to the inner leaflet of plasma membranes, thereby maintaining the asymmetric distribution of PtdSer. Here, we detected a de novo heterozygous point
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98d9500bf41887fe56bf82f95617abaf
https://pubmed.ncbi.nlm.nih.gov/34403372
https://pubmed.ncbi.nlm.nih.gov/34403372