Identification of a gene cluster for telomestatin biosynthesis and heterologous expression using a specific promoter in a clean host

Autor: Keita Amagai, Haruo Ikeda, Junko Hashimoto, Ikuko Kozone, Miho Izumikawa, Fumitaka Kudo, Tadashi Eguchi, Takemichi Nakamura, Hiroyuki Osada, Shunji Takahashi, Kazuo Shin-ya

Publikováno v: Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)

Abstract Telomestatin, a strong telomerase inhibitor with G-quadruplex stabilizing activity, is a potential therapeutic agent for treating cancers. Difficulties in isolating telomestatin from microbial cultures and in chemical synthesis are bottlenec

Externí odkaz: https://doaj.org/article/bc74afa0add84c29833f93ffbe2a2b0d

Qualitative evaluation of a package of implementation strategies codesigned to support the introduction of multiple micronutrient supplementation (MMS) for pregnant women in Bamako, Mali.

Autor: Ba A; Jhpiego, Bamako, Mali., Fox MJ; Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.; Vitamin Angel Alliance, Goleta, California, USA., Keita AM; Center for Vaccine Development, Bamako, Mali., Hurley KM; Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.; Vitamin Angel Alliance, Goleta, California, USA., King SE; Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.; Vitamin Angel Alliance, Goleta, California, USA., Sow S; Center for Vaccine Development, Bamako, Mali., Diarra K; Center for Vaccine Development, Bamako, Mali., Djiteye M; Center for Vaccine Development, Bamako, Mali., Kanté BS; Center for Vaccine Development, Bamako, Mali., Coulibaly M; Center for Vaccine Development, Bamako, Mali., Dembele O; Center for Vaccine Development, Bamako, Mali., Noguchi LM; Jhpiego, Baltimore, Maryland, USA., Sripad P; Jhpiego, Baltimore, Maryland, USA., Winch PJ; Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.

Publikováno v: Maternal & child nutrition [Matern Child Nutr] 2024 Aug 22, pp. e13712. Date of Electronic Publication: 2024 Aug 22.

Diarrhea Case Surveillance in the Enterics for Global Health Shigella Surveillance Study: Epidemiologic Methods.

Autor: Atlas HE; Department of Global Health, University of Washington, Seattle, Washington, USA., Conteh B; Medical Research Council Unit The Gambia, London School of Hygiene and Tropical Medicine, Fajara, The Gambia., Islam MT; Infectious Diseases Division, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh., Jere KC; Malawi Liverpool Wellcome Programme, Blantyre, Malawi.; Department of Clinical Infection, Microbiology and Immunology, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom.; Department of Medical Laboratory Sciences, Kamuzu University of Health Sciences, School of Life Sciences and Health Professions, Blantyre, Malawi., Omore R; Centre for Global Health Research, Kenya Medical Research Institute, Kisumu, Kenya., Sanogo D; Centre pour le Développement des Vaccins du Mali, Bamako, Mali., Schiaffino F; Faculty of Veterinary Medicine, Universidad Peruana Cayetano Heredia, Lima, Peru.; Division of Infectious Diseases and International Health University of Virginia, School of Medicine, Charlottesville, Virginia, USA., Yousafzai MT; Department of Pediatrics and Child Health, The Aga Khan University, Karachi, Pakistan., Ahmed N; Department of Pediatrics and Child Health, The Aga Khan University, Karachi, Pakistan., Awuor AO; Centre for Global Health Research, Kenya Medical Research Institute, Kisumu, Kenya., Badji H; Medical Research Council Unit The Gambia, London School of Hygiene and Tropical Medicine, Fajara, The Gambia., Cornick J; Malawi Liverpool Wellcome Programme, Blantyre, Malawi.; Department of Clinical Infection, Microbiology and Immunology, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom., Feutz E; Department of Global Health, University of Washington, Seattle, Washington, USA., Galagan SR; Department of Global Health, University of Washington, Seattle, Washington, USA., Haidara FC; Centre pour le Développement des Vaccins du Mali, Bamako, Mali., Horne B; Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, USA.; Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA., Hossen MI; Infectious Diseases Division, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh., Hotwani A; Department of Pediatrics and Child Health, The Aga Khan University, Karachi, Pakistan., Houpt ER; Division of Infectious Diseases and International Health University of Virginia, School of Medicine, Charlottesville, Virginia, USA., Jallow AF; Medical Research Council Unit The Gambia, London School of Hygiene and Tropical Medicine, Fajara, The Gambia., Karim M; Medical Research Council Unit The Gambia, London School of Hygiene and Tropical Medicine, Fajara, The Gambia., Keita AM; Centre pour le Développement des Vaccins du Mali, Bamako, Mali., Keita Y; Centre pour le Développement des Vaccins du Mali, Bamako, Mali., Khanam F; Infectious Diseases Division, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh., Liu J; School of Public Health, Qingdao University, Qingdao, China., Malemia T; Malawi Liverpool Wellcome Programme, Blantyre, Malawi., Manneh A; Medical Research Council Unit The Gambia, London School of Hygiene and Tropical Medicine, Fajara, The Gambia., McGrath CJ; Department of Global Health, University of Washington, Seattle, Washington, USA., Nasrin D; Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, USA., Ndalama M; Malawi Liverpool Wellcome Programme, Blantyre, Malawi., Ochieng JB; Centre for Global Health Research, Kenya Medical Research Institute, Kisumu, Kenya., Ogwel B; Centre for Global Health Research, Kenya Medical Research Institute, Kisumu, Kenya., Paredes Olortegui M; Asociación Benéfica PRISMA, Iquitos, Loreto, Peru., Zegarra Paredes LF; Asociación Benéfica PRISMA, Iquitos, Loreto, Peru., Pinedo Vasquez T; Asociación Benéfica PRISMA, Iquitos, Loreto, Peru., Platts-Mills JA; Division of Infectious Diseases and International Health University of Virginia, School of Medicine, Charlottesville, Virginia, USA., Qudrat-E-Khuda S; Infectious Diseases Division, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh., Qureshi S; Department of Pediatrics and Child Health, The Aga Khan University, Karachi, Pakistan., Hasan Rajib MN; Infectious Diseases Division, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh., Rogawski McQuade ET; Department of Epidemiology, Emory University, Atlanta, Georgia, USA., Sultana S; Department of Pediatrics and Child Health, The Aga Khan University, Karachi, Pakistan., Tennant SM; Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, USA.; Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA., Tickell KD; Department of Global Health, University of Washington, Seattle, Washington, USA., Witte D; Malawi Liverpool Wellcome Programme, Blantyre, Malawi.; Department of Clinical Infection, Microbiology and Immunology, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom., Peñataro Yori P; Division of Infectious Diseases and International Health University of Virginia, School of Medicine, Charlottesville, Virginia, USA., Cunliffe NA; Department of Clinical Infection, Microbiology and Immunology, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom., Hossain MJ; Medical Research Council Unit The Gambia, London School of Hygiene and Tropical Medicine, Fajara, The Gambia., Kosek MN; Division of Infectious Diseases and International Health University of Virginia, School of Medicine, Charlottesville, Virginia, USA., Kotloff KL; Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, USA.; Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA.; Department of Pediatrics, University of Maryland School of Medicine, Baltimore, Maryland, USA., Qadri F; Infectious Diseases Division, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh., Qamar FN; Department of Pediatrics and Child Health, The Aga Khan University, Karachi, Pakistan., Tapia MD; Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, USA.; Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA.; Department of Pediatrics, University of Maryland School of Medicine, Baltimore, Maryland, USA., Pavlinac PB; Department of Global Health, University of Washington, Seattle, Washington, USA.

Publikováno v: Open forum infectious diseases [Open Forum Infect Dis] 2024 Mar 25; Vol. 11 (Suppl 1), pp. S6-S16. Date of Electronic Publication: 2024 Mar 25 (Print Publication: 2024).

Post-mortem investigation of deaths due to pneumonia in children aged 1-59 months in sub-Saharan Africa and South Asia from 2016 to 2022: an observational study.

Autor: Mahtab S; South African Medical Research Council Vaccines and Infectious Diseases Analytics Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa., Blau DM; Global Health Center, Centers for Disease Control and Prevention, Atlanta, GA, USA., Madewell ZJ; Global Health Center, Centers for Disease Control and Prevention, Atlanta, GA, USA., Ogbuanu I; Crown Agents, Freetown, Sierra Leone., Ojulong J; ICAP - Columbia University, Makeni, Sierra Leone., Lako S; Aberdeen Women's Centre, Freetown, Sierra Leone., Legesse H; UNICEF Sierra Leone, Freetown, Sierra Leone., Bangura JS; Caritas International-Sierra Leone, Freetown, Sierra Leone., Bassat Q; Centro de Investigação em Saúde de Manhiça, Maputo, Mozambique; ISGlobal - Hospital Clínic, Unversitat de Barcelona, Barcelona, Spain; Institutó Catalana de Recerca I Estudis Avançats, Barcelona, Spain; Pediatrics Department, Hospital Sant Joan de Déu, Universitat de Barcelona, Esplugues, Barcelona, Spain; Consorcio de Investigación Biomédica en Red de Epidemiología y Salud Pública, Madrid, Spain., Mandomando I; Centro de Investigação em Saúde de Manhiça, Maputo, Mozambique; Instituto Nacional de Saúde, Maputo, Mozambique., Xerinda E; Centro de Investigação em Saúde de Manhiça, Maputo, Mozambique., Fernandes F; Department of Pathology, Maputo Central Hospital, Maputo, Mozambique., Varo R; Centro de Investigação em Saúde de Manhiça, Maputo, Mozambique; ISGlobal - Hospital Clínic, Unversitat de Barcelona, Barcelona, Spain., Sow SO; Centre pour le Développement des Vaccins, Ministère de la Santé, Bamako, Mali., Kotloff KL; Department of Pediatrics and Department of Medicine, Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, MD, USA., Tapia MD; Department of Pediatrics and Department of Medicine, Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, MD, USA., Keita AM; Centre pour le Développement des Vaccins, Ministère de la Santé, Bamako, Mali., Sidibe D; Centre pour le Développement des Vaccins, Ministère de la Santé, Bamako, Mali., Onyango D; Kisumu County Department of Health, Kisumu, Kenya., Akelo V; Centers for Disease Control and Prevention-Kenya, Kisumu, Kenya., Gethi D; Kenya Medical Research Institute-Center for Global Health Research (KEMRI-CGHR), Kisumu, Kenya., Verani JR; National Center for Immunization and Respiratory Disease, Centers for Disease Control and Prevention, Atlanta, GA, USA., Revathi G; Department of Pathology, Aga Khan University, Nairobi, Kenya., Scott JAG; Department of Infectious Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, UK., Assefa N; College of Health and Medical Sciences, Haramaya University, Harar, Ethiopia., Madrid L; Department of Infectious Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, UK; College of Health and Medical Sciences, Haramaya University, Harar, Ethiopia., Bizuayehu H; Department of Microbiology, Addis Ababa Burn, Emergency and Trauma Hospital, Addis Ababa, Ethiopia., Tirfe TT; College of Health and Medical Sciences, Haramaya University, Harar, Ethiopia., El Arifeen S; International Center for Diarrhoeal Diseases Research, Dhaka, Bangladesh., Gurley ES; International Center for Diarrhoeal Diseases Research, Dhaka, Bangladesh; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA., Islam KM; International Center for Diarrhoeal Diseases Research, Dhaka, Bangladesh., Alam M; International Center for Diarrhoeal Diseases Research, Dhaka, Bangladesh., Zahid Hossain M; International Center for Diarrhoeal Diseases Research, Dhaka, Bangladesh., Dangor Z; South African Medical Research Council Vaccines and Infectious Diseases Analytics Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa., Baillie VL; South African Medical Research Council Vaccines and Infectious Diseases Analytics Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa., Hale M; National Health Laboratory Service, Department of Anatomical Pathology, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa., Mutevedzi P; Emory Global Health Institute, Emory University, Atlanta, Georgia, USA., Breiman RF; Wits Infectious Diseases and Oncology Research Institute, University of the Witwatersrand, Faculty of Health Sciences, Johannesburg, South Africa., Whitney CG; Emory Global Health Institute, Emory University, Atlanta, Georgia, USA., Madhi SA; South African Medical Research Council Vaccines and Infectious Diseases Analytics Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa; Wits Infectious Diseases and Oncology Research Institute, University of the Witwatersrand, Faculty of Health Sciences, Johannesburg, South Africa. Electronic address: shabir.madhi@wits-vida.org.

Publikováno v: The Lancet. Child & adolescent health [Lancet Child Adolesc Health] 2024 Mar; Vol. 8 (3), pp. 201-213. Date of Electronic Publication: 2024 Jan 25.

Identifying delays in healthcare seeking and provision: The Three Delays-in-Healthcare and mortality among infants and children aged 1-59 months.

Autor: Garcia Gomez E; Emory University School of Medicine, Emory University, Atlanta, Georgia, United States of America., Igunza KA; Kenya Medical Research Institute-Center for Global Health Research, Kisumu, Kenya., Madewell ZJ; Global Health Center, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America., Akelo V; Centers for Disease Control and Prevention-Kenya, Kisumu, Kenya., Onyango D; Kisumu County Department of Health, Kisumu, Kenya., El Arifeen S; International Centre for Diarrhoeal Disease Research Bangladesh (icddr,b), Dhaka, Bangladesh., Gurley ES; Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America., Hossain MZ; International Centre for Diarrhoeal Disease Research Bangladesh (icddr,b), Dhaka, Bangladesh., Chowdhury MAI; International Centre for Diarrhoeal Disease Research Bangladesh (icddr,b), Dhaka, Bangladesh., Islam KM; International Centre for Diarrhoeal Disease Research Bangladesh (icddr,b), Dhaka, Bangladesh., Assefa N; London School of Hygiene and Tropical Medicine, London, United Kingdom.; College of Health and Medical Sciences, Haramaya University, Harar, Ethiopia.; Hararghe Health Research, Haramaya University, Harar, Ethiopia., Scott JAG; London School of Hygiene and Tropical Medicine, London, United Kingdom., Madrid L; London School of Hygiene and Tropical Medicine, London, United Kingdom.; College of Health and Medical Sciences, Haramaya University, Harar, Ethiopia.; Hararghe Health Research, Haramaya University, Harar, Ethiopia., Tilahun Y; College of Health and Medical Sciences, Haramaya University, Harar, Ethiopia.; Hararghe Health Research, Haramaya University, Harar, Ethiopia., Orlien S; College of Medicine and Health Sciences, University of Hargeisa, Hargeisa, Somaliland.; Department of Paediatrics, Vestfold Hospital Trust, Tønsberg, Norway., Kotloff KL; Department of Pediatrics, Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, United States of America., Tapia MD; Department of Pediatrics, Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, United States of America., Keita AM; Centre pour le Développement des Vaccins-Mali, Bamako, Mali., Mehta A; Department of Pediatrics, Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, United States of America., Magaço A; Centro de Investigação em Saúde de Manhiça (CISM), Maputo, Mozambique., Torres-Fernandez D; Centro de Investigação em Saúde de Manhiça (CISM), Maputo, Mozambique.; ISGlobal - Hospital Clínic, Universitat de Barcelona, Barcelona, Spain., Nhacolo A; Centro de Investigação em Saúde de Manhiça (CISM), Maputo, Mozambique., Bassat Q; Centro de Investigação em Saúde de Manhiça (CISM), Maputo, Mozambique.; ISGlobal - Hospital Clínic, Universitat de Barcelona, Barcelona, Spain.; Institució Catalana de Recerca I Estudis Avançats (ICREA), Barcelona, Spain.; Pediatrics Department, Hospital Sant Joan de Déu, Universitat de Barcelona, Esplugues, Barcelona, Spain.; Consorcio de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain., Mandomando I; Centro de Investigação em Saúde de Manhiça (CISM), Maputo, Mozambique.; ISGlobal - Hospital Clínic, Universitat de Barcelona, Barcelona, Spain.; Instituto Nacional de Saúde, Ministério de Saúde, Maputo, Moçambique., Ogbuanu I; Crown Agents, Freetown, Sierra Leone., Cain CJ; World Hope International, Freetown, Sierra Leone., Luke R; Ministry of Health and Sanitation, Freetown, Sierra Leone., Kamara SIB; Crown Agents, Freetown, Sierra Leone., Legesse H; UNICEF, Freetown, Sierra Leone., Madhi S; South African Medical Research Council Vaccines and Infectious Diseases Analytics Research Unit, University of the Witwatersrand, Johannesburg, South Africa., Dangor Z; South African Medical Research Council Vaccines and Infectious Diseases Analytics Research Unit, University of the Witwatersrand, Johannesburg, South Africa., Mahtab S; South African Medical Research Council Vaccines and Infectious Diseases Analytics Research Unit, University of the Witwatersrand, Johannesburg, South Africa., Wise A; Department of Obstetrics and Gynaecology, Rahima Mossa Mother and Child Hospital, University of the Witwatersrand, Johannesburg, South Africa., Adam Y; Department of Obstetrics and Gynaecology, Chris Hani Baragwanath Academic Hospital, University of the Witwatersrand, Johannesburg, South Africa., Whitney CG; Global Health Institute, Emory University, Atlanta, Georgia, United States of America., Mutevedzi PC; Global Health Institute, Emory University, Atlanta, Georgia, United States of America., Blau DM; Global Health Center, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America., Breiman RF; Hubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, Georgia, United States of America., Tippett Barr BA; Nyanja Health Research Institute, Salima, Malawi., Rees CA; Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, United States of America.; Children's Healthcare of Atlanta, Atlanta, Georgia, United States of America.

Publikováno v: PLOS global public health [PLOS Glob Public Health] 2024 Feb 08; Vol. 4 (2), pp. e0002494. Date of Electronic Publication: 2024 Feb 08 (Print Publication: 2024).