Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Keit Men Wong"'
Publikováno v:
Neural Regeneration Research, Vol 12, Iss 4, Pp 518-524 (2017)
Axonal degeneration is a pivotal feature of many neurodegenerative conditions and substantially accounts for neurological morbidity. A widely used experimental model to study the mechanisms of axonal degeneration is Wallerian degeneration (WD), which
Externí odkaz:
https://doaj.org/article/277a509096434c16b5c7c511c3e15ebd
Autor:
Keit Men Wong, Bogdan Beirowski
Publikováno v:
Communicative & Integrative Biology, Vol 11, Iss 1 (2018)
During nerve development, Schwann cells (SCs) build multilayered myelin sheaths around axons to accelerate nerve conduction. The mechanistic target of rapamycin complex 1 (mTORC1) downstream of PI3K/AKT signaling lately emerged as a central anabolic
Externí odkaz:
https://doaj.org/article/6763dcfda0df47f682d5baaed4463c61
Autor:
Keit Men Wong, Wayne M Jepsen, Stephanie Efthymiou, Vincenzo Salpietro, Meredith Sanchez-Castillo, Janice Yip, Yamna Kriouile, Susann Diegmann, Steffi Dreha-Kulaczewski, Janine Altmüller, Holger Thiele, Peter Nürnberg, Mehran Beiraghi Toosi, Javad Akhondian, Ehsan Ghayoor Karimiani, Hannah Hummel-Abmeier, Brenda Huppke, Henry Houlden, Jutta Gärtner, Reza Maroofian, Peter Huppke
Publikováno v:
Brain. 145:3022-3034
TAF8 is part of the transcription factor II D complex, composed of the TATA-binding protein and 13 TATA-binding protein–associated factors (TAFs). Transcription factor II D is the first general transcription factor recruited at promoters to assembl
Publikováno v:
Nature Neuroscience. 24:150-153
Autor:
Senthilvelan Manohar, Richard Salvi, Chet C. Sherwood, Joan S. Baizer, Keit Men Wong, Patrick R. Hof, Sandra F. Witelson, James F. Baker
Publikováno v:
The Anatomical Record. 301:862-886
The mammalian cochlear nuclei (CN) consist of two major subdivisions, the dorsal (DCN) and ventral (VCN) nuclei. We previously reported differences in the structural and neurochemical organization of the human DCN from that in several other species.
Publikováno v:
Nat Neurosci
Axon degeneration is a hallmark of many neurodegenerative disorders. The current assumption is that the decision of injured axons to degenerate is cell-autonomously regulated. Here we show that Schwann cells (SCs), the glia of the peripheral nervous
Autor:
Sarah H. Hayes, Joan S. Baizer, Dalian Ding, Senthilvelan Manohar, Richard Salvi, Robert K. Dingman, Keit Men Wong
Publikováno v:
Neuroscience. 303:299-311
Exposure to loud, prolonged sounds (acoustic trauma, AT) leads to the death of both inner and outer hair cells (IHCs and OHCs), death of neurons of the spiral ganglion and degeneration of the auditory nerve. The auditory nerve (8cn) projects to the t
Autor:
Bogdan Beirowski, Keit Men Wong
Publikováno v:
Cell cycle (Georgetown, Tex.). 16(18)
The myelination of axons is essential for neuronal wiring and normal nervous system functions. In the peripheral nervous system, Schwann cells (SCs) form myelin sheaths around axons during nerve development. Such myelination is compromised in a numbe
Autor:
Joan S, Baizer, Keit Men, Wong, Richard J, Salvi, Senthilvelan, Manohar, Chet C, Sherwood, Patrick R, Hof, James F, Baker, Sandra F, Witelson
Publikováno v:
Anatomical record (Hoboken, N.J. : 2007). 301(5)
The mammalian cochlear nuclei (CN) consist of two major subdivisions, the dorsal (DCN) and ventral (VCN) nuclei. We previously reported differences in the structural and neurochemical organization of the human DCN from that in several other species.
Autor:
Sandra F. Witelson, Richard Salvi, Keit Men Wong, Nadav I. Weinstock, Senthilvelan Manohar, James F. Baker, Chet C. Sherwood, Patrick R. Hof, Nicholas A. Paolone, Joan S. Baizer
Publikováno v:
The Anatomical Record. 297:1865-1884
The dorsal cochlear nucleus (DCN) is a brainstem structure that receives input from the auditory nerve. Many studies in a diversity of species have shown that the DCN has a laminar organization and identifiable neuron types with predictable synaptic