Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Keisuke Wakusawa"'
VLDL-specific increases of fatty acids in autism spectrum disorder correlate with social interaction
Autor:
Noriyoshi Usui, Keiko Iwata, Taishi Miyachi, Shu Takagai, Keisuke Wakusawa, Takahiro Nara, Kenji J. Tsuchiya, Kaori Matsumoto, Daisuke Kurita, Yosuke Kameno, Tomoyasu Wakuda, Kiyokazu Takebayashi, Yasuhide Iwata, Toru Fujioka, Takaharu Hirai, Manabu Toyoshima, Tetsuo Ohnishi, Tomoko Toyota, Motoko Maekawa, Takeo Yoshikawa, Masato Maekawa, Kazuhiko Nakamura, Masatsugu Tsujii, Toshiro Sugiyama, Norio Mori, Hideo Matsuzaki
Publikováno v:
EBioMedicine, Vol 58, Iss , Pp 102917- (2020)
Background: Abnormalities of lipid metabolism contributing to the autism spectrum disorder (ASD) pathogenesis have been suggested, but the mechanisms are not fully understood. We aimed to characterize the lipid metabolism in ASD and to explore a biom
Externí odkaz:
https://doaj.org/article/aecdbe3a4a7d484094a99cf824b2f652
Sensory Processing Patterns and Fusiform Activity During Face Processing in Autism Spectrum Disorder
Autor:
Katsuaki Suzuki, Keisuke Wakusawa, Masatsugu Tsujii, Kenji J. Tsuchiya, Ayaka Kuno‐Fujita, Toshiki Iwabuchi, Kosaka Hirotaka, Hiroyuki Ito, Akira Shigetomi
Publikováno v:
Autism Research
A growing body of evidence has indicated that individuals with autism spectrum disorder (ASD) exhibit abnormal reactions to sensory stimuli and impaired face processing. Although behavioral studies have reported that individual differences in sensory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e3212092c3c59f7b79e6073d801ab3e
https://doi.org/10.1002/aur.2283
https://doi.org/10.1002/aur.2283
Autor:
Yumiko Nagano, Daisuke Kurita, Shigeru Oowada, Hiromu Ito, Keiko Iwata, Aki Hirayama, Kenji Tsuchiya, Keisuke Wakusawa, Yosuke Kameno, Toru Fujioka, Tomoyasu Wakuda, Noriyoshi Usui, Hideo Matsuzaki, Masatsugu Tsujii, Takaharu Hirai, Shu Takagai, Takahiro Nara
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports
Scientific Reports
This case–control study aimed to assess oxidative stress alterations in autism spectrum disorder (ASD). We used the MULTIS method, an electron spin resonance-based technique measuring multiple free radical scavenging activities simultaneously, in c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbeced97db710ac235bab58e89590bf4
https://doi.org/10.1038/s41598-020-77328-z
https://doi.org/10.1038/s41598-020-77328-z
Autor:
Toshiro Sugiyama, Keiko Iwata, Manabu Toyoshima, Usui Noriyoshi, Kaori Matsumoto, Masato Maekawa, Tomoyasu Wakuda, Takaharu Hirai, Hideo Matsuzaki, Daisuke Kurita, Toru Fujioka, Norio Mori, Shu Takagai, Motoko Maekawa, Takahiro Nara, Takeo Yoshikawa, Taishi Miyachi, Kazuhiko Nakamura, Kiyokazu Takebayashi, Yasuhide Iwata, Kenji J. Tsuchiya, Tetsuo Ohnishi, Tomoko Toyota, Yosuke Kameno, Masatsugu Tsujii, Keisuke Wakusawa
Publikováno v:
SSRN Electronic Journal.
Abnormalities of lipid metabolism contribute to ASD pathogenesis has been argued, but the mechanisms are not fully understood. We characterized the lipids metabolism in ASD children by lipidomics, and identified the dramatic alterations of 71 metabol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44a0d5bc52cd07f8dc46540a4ba7907d
https://doi.org/10.2139/ssrn.3582706
https://doi.org/10.2139/ssrn.3582706
Autor:
Mamiko Ishitobi, Takehiko Inui, Yosuke Kakisaka, Wakaba Endo, Kazuhiro Haginoya, Naomi Hino-Fukuyo, Nobukazu Nakasato, Mai Anzai, Keisuke Wakusawa, Yusuke Takezawa
Publikováno v:
Epilepsy & Seizure. 8:1-8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::620acd34badf5df42fe6a99bdffee24b
https://doi.org/10.3805/eands.8.1
https://doi.org/10.3805/eands.8.1
VLDL-specific increases of fatty acids in autism spectrum disorder correlate with social interaction
Autor:
Tomoyasu Wakuda, Noriyoshi Usui, Yasuhide Iwata, Yosuke Kameno, Kiyokazu Takebayashi, Norio Mori, Keiko Iwata, Taishi Miyachi, Toru Fujioka, Kenji J. Tsuchiya, Motoko Maekawa, Hideo Matsuzaki, Kaori Matsumoto, Kazuhiko Nakamura, Tomoko Toyota, Masatsugu Tsujii, Takahiro Nara, Takaharu Hirai, Shu Takagai, Daisuke Kurita, Keisuke Wakusawa, Masato Maekawa, Toshiro Sugiyama, Manabu Toyoshima, Takeo Yoshikawa, Tetsuo Ohnishi
Publikováno v:
EBioMedicine
EBioMedicine, Vol 58, Iss, Pp 102917-(2020)
EBioMedicine, Vol 58, Iss, Pp 102917-(2020)
Background Abnormalities of lipid metabolism contributing to the autism spectrum disorder (ASD) pathogenesis have been suggested, but the mechanisms are not fully understood. We aimed to characterize the lipid metabolism in ASD and to explore a bioma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37b44399fb98e4b4718654de2e59b5bd
https://doi.org/10.1016/j.ebiom.2020.102917
https://doi.org/10.1016/j.ebiom.2020.102917
Autor:
Kaoru Horie, Hyeonjeong Jeong, Hiroyuki Yokoyama, Motoaki Sugiura, Yukihito Yomogida, Ryuta Kawashima, Norio Mori, Noriyoshi Takei, Yuko Sassa, Keisuke Wakusawa, Shigeru Sato, Shigeo Kure
Publikováno v:
Neuroscience Research. 90:72-82
We investigated the neural mechanisms underlying the ability to cope in atypical or novel situations using tools. We hypothesized that two cognitive components support this ability: adaptive coordination (for adapting to situational demands) and cogn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53112e0ceed8494dfd3830bdea77a562
https://doi.org/10.1016/j.neures.2014.03.008
https://doi.org/10.1016/j.neures.2014.03.008
Autor:
Wakaba Endo, Atsuko Kato, Kazuhiro Haginoya, Keisuke Wakusawa, Hiroshi Oba, Noriko Togashi, Mitsuko Nakashima, Yukimune Okubo, Ryo Sato, Hirotomo Saitsu, Naomichi Matsumoto, Sato Suzuki-Muromoto, Takuya Miyabayashi, Takehiko Inui
Publikováno v:
Journal of human genetics. 63(6)
Here we report a Japanese patient with new compound heterozygous truncating variants in the PCDH12 gene. As compared to the previously reported families who had congenital microcephaly, intrauterine growth retardation, intracranial calcification, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0f60d049af13a98f3f1fb0a3defe08f
https://pubmed.ncbi.nlm.nih.gov/29904113
https://pubmed.ncbi.nlm.nih.gov/29904113
Autor:
Keisuke Wakusawa, Yuko Sassa, Yasuyuki Taki, Norio Mori, Noriyoshi Takei, Mieko Hirose, Satoru Kobayashi, Shigeo Kure, Yuki Kubota, Yayoi Tomizawa, Sato Suzuki-Muromoto, Chieko Nara, Ryuta Kawashima, Takahiro Nara, Hiroyuki Yokoyama
Publikováno v:
Braindevelopment. 40(1)
Objective Several studies have suggested that objective deficits in the processing of abstract information in conjunction with an enhanced ability to process concrete information is a definitive characteristic of autism spectrum disorder (ASD). Howev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d60196dbf26e9930c54f3c9f9418aa1c
https://pubmed.ncbi.nlm.nih.gov/28750723
https://pubmed.ncbi.nlm.nih.gov/28750723
Autor:
Atsuo Kikuchi, Takehiko Inui, Keisuke Wakusawa, Soichiro Tanaka, Kazuhiro Haginoya, Shinji Kunishima, Shigeo Kure, Satoru Kobayashi, Yu Abe
Publikováno v:
Developmental Medicine & Child Neurology. 56:1221-1224
Periventricular nodular heterotopia (PNH) with overlying polymicrogyria (PMG) is a recently described, developmental brain malformation; however, the causative genes of this malformation have not yet been identified. We report on a 5-year-old Japanes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc24c43b67bad387a7e0ac839aa99099
https://doi.org/10.1111/dmcn.12553
https://doi.org/10.1111/dmcn.12553