Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Keisuke TABATA"'
Autor:
Keisuke Tabata, Kenta Imai, Koki Fukuda, Kentaro Yamamoto, Hayato Kunugi, Toshiharu Fujita, Tatsuya Kaminishi, Christian Tischer, Beate Neumann, Sabine Reither, Fatima Verissimo, Rainer Pepperkok, Tamotsu Yoshimori, Maho Hamasaki
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Autophagy is a highly conserved process from yeast to mammals in which intracellular materials are engulfed by a double-membrane organelle called autophagosome and degrading materials by fusing with the lysosome. The process of autophagy is
Externí odkaz:
https://doaj.org/article/b4d8b0c4e94d4cd8bbae2e06891f916f
Autor:
Keisuke Tabata, Kenta Imai, Koki Fukuda, Kentaro Yamamoto, Hayato Kunugi, Toshiharu Fujita, Tatsuya Kaminishi, Christian Tischer, Beate Neumann, Sabine Reither, Fatima Verissimo, Rainer Pepperkok, Tamotsu Yoshimori, Maho Hamasaki
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/bfd3b12725a046d6ba979c3212f5662b
Autor:
Keisuke Tabata, Masaya Aoki, Ryo Miyata, Tadashi Umehara, Aya Harada-Takeda, Go Kamimura, Toshiyuki Nagata, Ryuya Okizono, Hideyuki Terazono, Yasuo Takeda, Takayuki Suetsugu, Kazuhiro Ueda, Masami Sato
Publikováno v:
Case Reports in Oncology, Vol 16, Iss 1, Pp 705-710 (2023)
Although osimertinib is a key drug in the treatment of non-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) mutation, the safety in hemodialysis patients has not been established. A 76-year-old man was diagnosed with NSCLC
Externí odkaz:
https://doaj.org/article/b5c78c72683442bba4cde407f911b044
Publikováno v:
STAR Protocols, Vol 4, Iss 2, Pp 102236- (2023)
Summary: Autophagy is an intracellular self-degradation process in which part of the cytoplasm, aggregates, or damaged organelles are degraded in lysosomes. Lysophagy is a specific form of selective autophagy responsible for clearing damaged lysosome
Externí odkaz:
https://doaj.org/article/894bba73fa71486f960726e7d419b6eb
Publikováno v:
Technologies, Vol 12, Iss 2, p 24 (2024)
The introduction of nanoparticles into the polymer matrix is a useful technique for creating highly functional composite membranes. Our research focuses on the development of nanoparticle-filled proton exchange membranes (PEMs). PEMs play a crucial r
Externí odkaz:
https://doaj.org/article/0663e534e98041ba8306c8ea61cb24ff
Autor:
Keisuke Tabata, Vibhu Prasad, David Paul, Ji-Young Lee, Minh-Tu Pham, Woan-Ing Twu, Christopher J. Neufeldt, Mirko Cortese, Berati Cerikan, Yannick Stahl, Sebastian Joecks, Cong Si Tran, Christian Lüchtenborg, Philip V’kovski, Katrin Hörmann, André C. Müller, Carolin Zitzmann, Uta Haselmann, Jürgen Beneke, Lars Kaderali, Holger Erfle, Volker Thiel, Volker Lohmann, Giulio Superti-Furga, Britta Brügger, Ralf Bartenschlager
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Double membrane vesicles (DMV) are used as replication organelles by several RNA viruses. Applying proteomics and lipidomics, Tabata and Prasad et al. find that two cellular acyltransferases (AGPAT1/2), responsible for synthesis of phosphatidic acid,
Externí odkaz:
https://doaj.org/article/004cd836b49b455dbee0043b2c9d12d0
Autor:
Tadashi Yamamuro, Tsuyoshi Kawabata, Atsunori Fukuhara, Shotaro Saita, Shuhei Nakamura, Hikari Takeshita, Mari Fujiwara, Yusuke Enokidani, Gota Yoshida, Keisuke Tabata, Maho Hamasaki, Akiko Kuma, Koichi Yamamoto, Iichiro Shimomura, Tamotsu Yoshimori
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Autophagic activity declines with age in several tissues and is linked to aging-associated functional decline and pathologies. Here the authors show that Rubicon, a negative regulator of autophagy, decreases in adipocytes with age, and its loss leads
Externí odkaz:
https://doaj.org/article/c769ddd694a94059b7f5b01f32cee145
Autor:
Che C Colpitts, Sophie Ridewood, Bethany Schneiderman, Justin Warne, Keisuke Tabata, Caitlin F Ng, Ralf Bartenschlager, David L Selwood, Greg J Towers
Publikováno v:
eLife, Vol 9 (2020)
Counteracting innate immunity is essential for successful viral replication. Host cyclophilins (Cyps) have been implicated in viral evasion of host antiviral responses, although the mechanisms are still unclear. Here, we show that hepatitis C virus (
Externí odkaz:
https://doaj.org/article/c5ebac21d95640d5911709dfca419d5e
Autor:
Jae Seung Lee, Keisuke Tabata, Woan-Ing Twu, Md Shafiqur Rahman, Hee Sun Kim, Jin Bae Yu, Min Hyeok Jee, Ralf Bartenschlager, Sung Key Jang
Publikováno v:
PLoS Pathogens, Vol 15, Iss 9, p e1008021 (2019)
Hepatitis C virus (HCV) is a positive-strand RNA virus replicating in a membranous replication organelle composed primarily of double-membrane vesicles (DMVs) having morphological resemblance to autophagosomes. To define the mechanism of DMV formatio
Externí odkaz:
https://doaj.org/article/ea0e91cd70c24d4e8559d3fff3592aba
Autor:
Ji-Young Lee, Mirko Cortese, Uta Haselmann, Keisuke Tabata, Inés Romero-Brey, Charlotta Funaya, Nicole L. Schieber, Yu Qiang, Marie Bartenschlager, Stephanie Kallis, Christian Ritter, Karl Rohr, Yannick Schwab, Alessia Ruggieri, Ralf Bartenschlager
Publikováno v:
Cell Reports, Vol 27, Iss 12, Pp 3602-3617.e5 (2019)
Summary: The hepatitis C virus (HCV) is a major cause of chronic liver disease, affecting around 71 million people worldwide. Viral RNA replication occurs in a membranous compartment composed of double-membrane vesicles (DMVs), whereas virus particle
Externí odkaz:
https://doaj.org/article/b47d6362fb914877b4724dfa3547b780