Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Keisuke Ohsumi"'
Autor:
Ikuko Nakamura, Kiyomitsu Katsumata, Hikaru Mitori, Shinobu Takeda, Satoru Matsumoto, Keisuke Ohsumi, Souichiro Akamatsu, Toru Nakai
Publikováno v:
Antimicrobial Agents and Chemotherapy. 63
Current therapies against invasive pulmonary aspergillosis (IPA) have a limited cure rate. Given that a delay in treatment initiation may be fatal, a new drug with rapid-onset and potent fungicidal activity is needed. The novel cyclic hexapeptide ASP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11a1aca61d68e937d4997e9925f308a6
https://doi.org/10.1128/aac.02689-18
https://doi.org/10.1128/aac.02689-18
Autor:
Ikuko, Nakamura, Keisuke, Ohsumi, Shinobu, Takeda, Kiyomitsu, Katsumata, Satoru, Matsumoto, Souichiro, Akamatsu, Hikaru, Mitori, Toru, Nakai
Publikováno v:
Antimicrobial agents and chemotherapy. 63(10)
Current therapies against invasive pulmonary aspergillosis (IPA) have a limited cure rate. Given that a delay in treatment initiation may be fatal, a new drug with rapid-onset and potent fungicidal activity is needed. The novel cyclic hexapeptide ASP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::14b00da56ec492fa3f72f53959c61bd5
https://pubmed.ncbi.nlm.nih.gov/31405853
https://pubmed.ncbi.nlm.nih.gov/31405853
Autor:
Akihiko Fujie, Shigetada Furukawa, Teruhisa Masaki, Keisuke Ohsumi, Ikuko Nakamura, Michizane Hashimoto, Seiji Yoshimura, Shigehiro Takase
Publikováno v:
The Journal of antibiotics. 70(1)
The novel antifungal agent ASP2397 (Vical's compound ID VL-2397) is produced by the fungal strain MF-347833 that was isolated from Malaysian leaf litter and is identified here as an Acremonium species based on its morphology, physiological properties
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a893779ce93338c8f1c0ac51ea4c00e
https://pubmed.ncbi.nlm.nih.gov/27599768
https://pubmed.ncbi.nlm.nih.gov/27599768
Autor:
Tomoko Nakanishi, Yasuhisa Tsurumi, Shigetada Furukawa, Keisuke Ohsumi, Motoaki Nishikawa, Motohiro Hino, Kana Murakami, Michizane Hashimoto, Osamu Nakayama, Shigehiro Takase
Publikováno v:
The Journal of Antibiotics. 58:497-502
FR258900 is a novel glycogen synthesis activator produced by Fungus No. 138354. This compound was isolated from the culture broth by solvent extraction and reverse-phase column chromatography. FR258900 stimulated glycogen synthesis and glycogen synth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a185babef95b55e3465ca3800d911b01
https://doi.org/10.1038/ja.2005.66
https://doi.org/10.1038/ja.2005.66
Autor:
Kiyotaka Fujine, Hirotsugu Ueda, Takashi Fujii, Michizane Hashimoto, Miho Tanaka, Keisuke Ohsumi, Shigehiro Takase, Motohiro Hino
Publikováno v:
The Journal of Antibiotics. 56:55-61
Novel immunosuppressive agents, FR252921, FR252922 and FR256523 were isolated from the cultured broth of a bacterial strain No. 408813. The strain was identified Pseudomonas fluorescens from morphological and physiological characteristics. FR252921,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::435ccd4e1a5157c0407c81ca9178b384
https://doi.org/10.7164/antibiotics.56.55
https://doi.org/10.7164/antibiotics.56.55
Publikováno v:
The Journal of antibiotics. 67(10)
AS2077715 is a novel antifungal metabolite produced by the newly isolated fungal strain Capnodium sp. 339855. This compound has potent inhibitory activity against Trichophyton mentagrophytes mitochondrial cytochrome bc1 complex (complex III) and pote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15773679f8b82b20ccf62e4c9be51008
https://pubmed.ncbi.nlm.nih.gov/24865864
https://pubmed.ncbi.nlm.nih.gov/24865864
Publikováno v:
The Journal of antibiotics. 67(10)
AS2077715 is a novel antifungal metabolite produced by the newly isolated fungal strain Capnodium sp. 339855. This compound has an analogous structure to funiculosin, an inhibitor of mitochondrial cytochrome bc1 complex (complex III). AS2077715 inhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c9b4c2e3863a6ef911046cf4bcc4dbc4
https://pubmed.ncbi.nlm.nih.gov/24865866
https://pubmed.ncbi.nlm.nih.gov/24865866
Publikováno v:
The Journal of antibiotics. 67(10)
A novel antifungal agent, AS2077715, was isolated from the fermentation broth of a fungal strain (339855) identified as a new Capnodium species based on morphological characteristics and large-subunit ribosomal DNA sequencing. AS2077715 was isolated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d74e1a19ecd2e4edf01bc100f329075d
https://pubmed.ncbi.nlm.nih.gov/24865863
https://pubmed.ncbi.nlm.nih.gov/24865863
Publikováno v:
Biotechnology Techniques. 12:91-95
A novel bioassay system for estimating concentrations of several heavy metal ions was carried out with yeast mutants which are highly sensitive to heavy metal ions. The method does not need an atomic adsorption spectrometer or other special equipment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5683732c03e2d06100be4ea48bce3124
https://doi.org/10.1023/a:1008872029860
https://doi.org/10.1023/a:1008872029860
Autor:
Akihiko Fujie, Shigehiro Takase, Toshiko Yamada, Keisuke Ohsumi, Michizane Hashimoto, Hideyuki Muramatsu, Kazutoshi Sakamoto, Hiroaki Mori, Satoshi Sasamura, Motohiro Hino, Takashi Fujii
Publikováno v:
The Journal of antibiotics. 63(11)
We screened actinomycetes capable of converting AS1387392 to AS1429716 and identified those strains capable of hydroxylation. Amycolatopsis azurea JCM 3275 was found to be a particularly efficient strain, capable of converting AS1387392 to AS1429716,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab9c5ee7c7f8a52b0001b98e07f7d4f4
https://pubmed.ncbi.nlm.nih.gov/20924384
https://pubmed.ncbi.nlm.nih.gov/20924384