Zobrazeno 1 - 10
of 148
pro vyhledávání: '"Keisuke Oe"'
Autor:
Yuya Yamamoto, Tomoaki Fukui, Kenichi Sawauchi, Ryo Yoshikawa, Kyohei Takase, Yohei Kumabe, Akihiro Maruo, Takahiro Niikura, Ryosuke Kuroda, Keisuke Oe
Publikováno v:
Bone & Joint Research, Vol 13, Iss 3, Pp 92-101 (2024)
Aims: Continuous local antibiotic perfusion (CLAP) has recently attracted attention as a new drug delivery system for orthopaedic infections. CLAP is a direct continuous infusion of high-concentration gentamicin (1,200 μg/ml) into the bone marrow. A
Externí odkaz:
https://doaj.org/article/4c62fc4f24ea429ba3beee03af8be57d
Autor:
Ryosuke Kuroda, Takahiro Niikura, Tomoyuki Matsumoto, Tomoaki Fukui, Keisuke Oe, Yutaka Mifune, Hironobu Minami, Hiroshi Matsuoka, Kimikazu Yakushijin, Yoshiharu Miyata, Shinichiro Kawamoto, Tatsuo Kagimura, Yasuyuki Fujita, Atsuhiko Kawamoto
Publikováno v:
BMC Medicine, Vol 21, Iss 1, Pp 1-16 (2023)
Abstract Background We previously demonstrated that CD34 + cell transplantation in animals healed intractable fractures via osteogenesis and vasculogenesis; we also demonstrated the safety and efficacy of this cell therapy in an earlier phase I/II cl
Externí odkaz:
https://doaj.org/article/ea3ea946858643d39d493415861b4c62
Autor:
Ryo Yoshikawa, Tomoaki Fukui, Keisuke Oe, Yohei Kumabe, Takahiro Oda, Kenichi Sawauchi, Kyohei Takase, Yuya Yamamoto, Yoshitada Sakai, Ryosuke Kuroda, Takahiro Niikura
Publikováno v:
Current Issues in Molecular Biology, Vol 44, Iss 11, Pp 5562-5578 (2022)
In this study, we examined the proliferation capability and osteogenic and chondrogenic differentiation potential of non-hypertrophic nonunion cells (NHNCs), and the effect of Escherichia coli-derived BMP-2 (E-BMP-2) on them. We enrolled five patient
Externí odkaz:
https://doaj.org/article/1eabe1142eb344afb1c1ca68b7c75140
Autor:
Tomoaki Fukui, Keisuke Oe, Teruya Kawamoto, Masayuki Morishita, Ikuo Fujita, Shunsuke Takahara, Atsushi Sakurai, Takashi Iwakura, Keiji Yoshida, Kenjiro Ito, Etsuo Shoda, Takafumi Hiranaka, Masaya Tsunoda, Ryosuke Kuroda, Takahiro Niikura
Publikováno v:
Journal of Bone Oncology, Vol 40, Iss , Pp 100478- (2023)
Bone-modifying agents (BMAs), with bone-resorptive inhibitory effects, such as zoledronic acid and denosumab, are widely used at higher doses for bone-related events caused by bone metastasis of malignant tumors. These drugs have been suggested to be
Externí odkaz:
https://doaj.org/article/5a1f8e4d4514423fa2d9a2f5d745bf13
Autor:
Takahiro Niikura, Takahiro Oda, Naoe Jimbo, Masato Komatsu, Keisuke Oe, Tomoaki Fukui, Tomoyuki Matsumoto, Shinya Hayashi, Takehiko Matsushita, Tomoo Itoh, Ryosuke Kuroda
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 17, Iss 1, Pp 1-12 (2022)
Abstract Background Induced membrane (IM) is the key component of Masquelet reconstruction surgery for the treatment of bone defects. IM is formed around the cement spacer and is known to secrete growth factors and osteoinductive factors. However, th
Externí odkaz:
https://doaj.org/article/79e82ca05b2e44b89da7870a15e8351a
Autor:
Akihiro Maruo, Takahiro Oda, Ryowa Mineo, Hidetoshi Miya, Hirotsugu Muratsu, Tomoaki Fukui, Keisuke Oe, Ryosuke Kuroda, Takahiro Niikura
Publikováno v:
Journal of Orthopaedic Surgery, Vol 30 (2022)
Purpose Fracture-related infections are difficult to treat because of the formation of biofilms around implants. Systemic antibiotics are notoriously ineffective against biofilms due to their insufficient penetration of tissues with poor vascularity.
Externí odkaz:
https://doaj.org/article/81585e14753d40a99e3d8c2682017797
Autor:
Yu Hirata, Kazuhiro Nomura, Daisuke Kato, Yoshihisa Tachibana, Takahiro Niikura, Kana Uchiyama, Tetsuya Hosooka, Tomoaki Fukui, Keisuke Oe, Ryosuke Kuroda, Yuji Hara, Takahiro Adachi, Koji Shibasaki, Hiroaki Wake, Wataru Ogawa
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 10 (2022)
Although immobility is a common cause of muscle atrophy, the mechanism underlying this causality is unclear. We here show that Krüppel-like factor 15 (KLF15) and IL-6 are upregulated in skeletal muscle of limb-immobilized mice and that mice with KLF
Externí odkaz:
https://doaj.org/article/bb1cf92118f84aac8bc9507c468e1c5e
Autor:
Takahiro Niikura, Naoe Jimbo, Masato Komatsu, Keisuke Oe, Tomoaki Fukui, Tomoyuki Matsumoto, Shinya Hayashi, Takehiko Matsushita, Yoshitada Sakai, Tomoo Itoh, Ryosuke Kuroda
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 16, Iss 1, Pp 1-9 (2021)
Abstract Background Rich vascularity of the induced membrane (IM) is important for Masquelet reconstruction surgery. The factors affecting IM vascularity are not completely understood. This study aimed to investigate these factors using histological
Externí odkaz:
https://doaj.org/article/6701893b39114825b90d5e41469f9f9a
Autor:
Keisuke Oe, Feibi Zeng, Tomoaki Fukui, Munenobu Nogami, Takamichi Murakami, Tomoyuki Matsumoto, Ryosuke Kuroda, Takahiro Niikura
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 16, Iss 1, Pp 1-6 (2021)
Abstract Background Recently, a standardized uptake value (SUV) has been used to evaluate bone single-photon emission computed tomography (SPECT). The aim of this study was to investigate quantitative SPECT imaging of uninfected nonunion to compare h
Externí odkaz:
https://doaj.org/article/9d110fcd32a7432fbb361f7b1b7f7d4b
Autor:
Keisuke Oe, Feibi Zeng, Takahiro Niikura, Tomoaki Fukui, Kenichi Sawauchi, Tomoyuki Matsumoto, Munenobu Nogami, Takamichi Murakami, Ryosuke Kuroda
Publikováno v:
Journal of Clinical Medicine, Vol 11, Iss 22, p 6732 (2022)
When visualizing biological activity at nonunion sites by the radioisotopes, gamma rays are more attenuated if metal implants are placed in the bone. However, the effects of various implant types and their placement on gamma ray attenuation in quanti
Externí odkaz:
https://doaj.org/article/7c3ee8846ebe4258b38201165ec8fa00