Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Keisuke Nozawa"'
Autor:
Keisuke Nozawa, Takahide Suzuki, Gen Kayanuma, Hiroki Yamamoto, Kazuki Nagayasu, Hisashi Shirakawa, Shuji Kaneko
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
Recent studies have suggested that dipeptidyl peptidase 4 (DPP4) inhibitors increase the risk of development of bullous pemphigoid (BP), which is the most common autoimmune blistering skin disease; however, the associated mechanisms remain unclear, a
Externí odkaz:
https://doaj.org/article/d11d0e1019914db8b8e80d4eec6d8d88
Autor:
Yoshifumi Ueyama, Yutaka Ukaji, Keisuke Nozawa, Katsuya Maeda, Shohei Miwa, Tomohiro Ishikawa, Yuki Kitao, Tsuyoshi Adachi, Naoki Ogawa, Makoto Shiozaki, Yokota Masahiro, Yosuke Ogoshi, Seki Noriyoshi, Jun Nishihata, Akihiro Nomura
Publikováno v:
ACS Med Chem Lett
[Image: see text] Historically, modulation of transforming growth factor β (TGF-β) signaling has been deemed a rational strategy to treat many disorders, though few successful examples have been reported to date. This difficulty could be partially
Publikováno v:
Developmental Neurobiology. 77:1101-1113
Rett syndrome is a severe neurodevelopmental disorder. It is caused by a mutation in methyl-CpG binding protein 2 (MecP2), a transcriptional regulator that recruits protein complexes involved in histone modification and chromatin remodeling. However,
Autor:
Keisuke Nozawa, Chika Oki, Akira Matsuo, Satoru Noji, Makoto Shiozaki, Yukari Kimoto, Yoshihiro Ogawa, Mutsuyoshi Matsushita, Yuichi Shinozaki, Atsuo Tanimoto, Wataru Amano
Publikováno v:
Inflammation Research
Objective To evaluate the pharmacological properties of JTE-052, a novel Janus kinase (JAK) inhibitor. Methods The JAK inhibitory activity of JTE-052 was evaluated using recombinant human enzymes. The inhibitory effects on cytokine signaling pathways
Autor:
Tohru Yamamoto, Keiko Furukori, Roger J. Davis, Yoichi Araki, Toshiharu Suzuki, Tadashi Nakaya, Hidenori Taru, Kyoko Chiba, Masataka Kinjo, Saori Hata, Takahide Matsushima, Yuhki Saito, Seiichi Uchida, Keisuke Nozawa, Masahiko Araseki, Yasushi Okada, Angus C. Nairn
Publikováno v:
Molecular Biology of the Cell
APP associates with kinesin-1 via JIP1. In JIP1-decicient neurons, the fast velocity and high frequency of anterograde transport of APP cargo are impaired to reduced velocity and lower frequency, respectively. Interaction of JIP1 with KLC via two nov
Publikováno v:
Developmental Neurobiology. 73:911-920
Dpysls (CRMPs) that were initially identified as mediator proteins of Semaphorin3a (Sema3a) signaling are involved in neuronal polarity and axon elongation in cultured neurons. Previous studies have shown that knockdown of neuropilin1a, one of the se
Autor:
Keisuke, Nozawa, Yanbin, Lin, Ryota, Kubodera, Yuki, Shimizu, Hideomi, Tanaka, Toshio, Ohshima
Publikováno v:
Developmental neurobiology. 77(9)
Rett syndrome is a severe neurodevelopmental disorder. It is caused by a mutation in methyl-CpG binding protein 2 (MecP2), a transcriptional regulator that recruits protein complexes involved in histone modification and chromatin remodeling. However,
Publikováno v:
Developmental neurobiology. 73(12)
Dpysls (CRMPs) that were initially identified as mediator proteins of Semaphorin3a (Sema3a) signaling are involved in neuronal polarity and axon elongation in cultured neurons. Previous studies have shown that knockdown of neuropilin1a, one of the se
Autor:
Yumi, Watanabe, Yoshie, Kawahara, Daisuke, Hanada, Keisuke, Nozawa, Yutaka, Tomoda, Shuichi, Kino
Publikováno v:
Rinsho byori. The Japanese journal of clinical pathology. 60(11)
The rapidity of coagulation testing is important for use as appropriate substitution therapy in patients with, or at risk of critical bleeding requiring massive transfusion. Whereas the ordinary method of coagulation testing is known to be slow, in a
Autor:
Hidenori Taru, Kyoko Chiba, Masahiko Araseki, Toshiharu Suzuki, Keisuke Nozawa, Masataka Kinjo
Publikováno v:
Alzheimer's & Dementia. 7