Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Keisuke Kitakaze"'
Autor:
Keisuke Kitakaze, Hanif Ali, Raiki Kimoto, Yasuhiro Takenouchi, Hironobu Ishimaru, Atsushi Yamashita, Natsuo Ueda, Tamotsu Tanaka, Yasuo Okamoto, Kazuhito Tsuboi
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-12 (2023)
Abstract Cyclic phosphatidic acid (cPA) is a lipid mediator, which regulates adipogenic differentiation and glucose homeostasis by suppressing nuclear peroxisome proliferator-activated receptor γ (PPARγ). Glycerophosphodiesterase 7 (GDE7) is a Ca2+
Externí odkaz:
https://doaj.org/article/26306f7b7b7040c6a3b4e53f03e27a76
Autor:
Keisuke Kitakaze, Miho Oyadomari, Jun Zhang, Yoshimasa Hamada, Yasuhiro Takenouchi, Kazuhito Tsuboi, Mai Inagaki, Masanori Tachikawa, Yoshio Fujitani, Yasuo Okamoto, Seiichi Oyadomari
Publikováno v:
Molecular Metabolism, Vol 54, Iss , Pp 101338- (2021)
Objective: Activating transcription factor 4 (ATF4) is a transcriptional regulator of the unfolded protein response and integrated stress response (ISR) that promote the restoration of normal endoplasmic reticulum (ER) function. Previous reports demo
Externí odkaz:
https://doaj.org/article/a969aa576da64d7087e79b3e088c139c
Autor:
Keisuke Kitakaze, Kazuhito Tsuboi, Maho Tsuda, Yasuhiro Takenouchi, Hironobu Ishimaru, Yasuo Okamoto
Publikováno v:
Journal of Lipid Research, Vol 62, Iss , Pp 100141- (2021)
Lysophosphatidic acid (LPA) is a lipid mediator that regulates various processes, including cell migration and cancer progression. Autotaxin (ATX) is a lysophospholipase D-type exoenzyme that produces extracellular LPA. In contrast, glycerophosphodie
Externí odkaz:
https://doaj.org/article/24778526397149548f656fa5d4264a44
Autor:
Keisuke Kitakaze, Shusuke Taniuchi, Eri Kawano, Yoshimasa Hamada, Masato Miyake, Miho Oyadomari, Hirotatsu Kojima, Hidetaka Kosako, Tomoko Kuribara, Suguru Yoshida, Takamitsu Hosoya, Seiichi Oyadomari
Publikováno v:
eLife, Vol 8 (2019)
The endoplasmic reticulum (ER) is responsible for folding secretory and membrane proteins, but disturbed ER proteostasis may lead to protein aggregation and subsequent cellular and clinical pathologies. Chemical chaperones have recently emerged as a
Externí odkaz:
https://doaj.org/article/08f2c99617734a8fa9aa3dfa44a5e62f
Autor:
Takashi Kodama, Tadayasu Togawa, Takahiro Tsukimura, Ikuo Kawashima, Kazuhiko Matsuoka, Keisuke Kitakaze, Daisuke Tsuji, Kohji Itoh, Yo-Ichi Ishida, Minoru Suzuki, Toshihiro Suzuki, Hitoshi Sakuraba
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e29074 (2011)
To find a new biomarker of Tay-Sachs disease and Sandhoff disease. The lyso-GM2 ganglioside (lyso-GM2) levels in the brain and plasma in Sandhoff mice were measured by means of high performance liquid chromatography and the effect of a modified hexos
Externí odkaz:
https://doaj.org/article/8a1281c4473f400db85b8e7bfd12c6fd
Autor:
Akira Yamauchi, Keisuke Kitakaze, Shuichiro Okamoto, Kei Miyano, Hitomi Kato, Mizuho Kajikawa, Momoe Itsumi, Chikage Kawai, Futoshi Kuribayashi
Publikováno v:
Biochemical and Biophysical Research Communications. 587:78-84
An interaction between acute myeloid leukemia (AML) cells and endothelial cells in the bone marrow seems to play a critical role in chemosensitivity on leukemia treatment. The endothelial niche reportedly enhances the paracrine action of the soluble
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35cf5a229f83865fc700b852fac3b4de
https://doi.org/10.1016/j.bbrc.2021.11.090
https://doi.org/10.1016/j.bbrc.2021.11.090
Autor:
Keisuke Kitakaze, Hanif Ali, Raiki Kimoto, Yasuhiro Takenouchi, Hironobu Ishimaru, Atsushi Yamashita, Natsuo Ueda, Tamotsu Tanaka, Yasuo Okamoto, Kazuhito Tsuboi
Cyclic phosphatidic acid (cPA) is a lipid mediator, which regulates adipogenesis and glucose homeostasis by suppressing nuclear peroxisome proliferator-activated receptor γ (PPARγ). Glycerophosphodiesterase 7 (GDE7) is a Ca2+-dependent lysophosphol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3b65b319f83d8b8164c9ac3ca1becff
https://doi.org/10.21203/rs.3.rs-2152597/v1
https://doi.org/10.21203/rs.3.rs-2152597/v1
Autor:
Yasuhiro Takenouchi, Hironobu Ishimaru, Keisuke Kitakaze, Kazuhito Tsuboi, Maho Tsuda, Yasuo Okamoto
Publikováno v:
Journal of Lipid Research
Journal of Lipid Research, Vol 62, Iss, Pp 100141-(2021)
Journal of Lipid Research, Vol 62, Iss, Pp 100141-(2021)
Lysophosphatidic acid (LPA) is a lipid mediator that regulates various processes, including cell migration and cancer progression. Autotaxin (ATX) is a lysophospholipase D-type exoenzyme that produces extracellular LPA. In contrast, glycerophosphodie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::262c925e6e2468dc62f0c74c658197c1
http://europepmc.org/articles/PMC8591415
http://europepmc.org/articles/PMC8591415
Autor:
Yoshimasa Hamada, Jun Zhang, Seiichi Oyadomari, Mai Inagaki, Masanori Tachikawa, Miho Oyadomari, Yasuo Okamoto, Kazuhito Tsuboi, Yoshio Fujitani, Yasuhiro Takenouchi, Keisuke Kitakaze
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 54, Iss, Pp 101338-(2021)
Molecular Metabolism, Vol 54, Iss, Pp 101338-(2021)
Objective Activating transcription factor 4 (ATF4) is a transcriptional regulator of the unfolded protein response and integrated stress response (ISR) that promote the restoration of normal endoplasmic reticulum (ER) function. Previous reports demon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7323e89eb26219f72f13517adbd69d41
http://europepmc.org/articles/PMC8487982
http://europepmc.org/articles/PMC8487982
Publikováno v:
The FASEB Journal. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8880b4432f8f669c6130b84e1783e0ac
https://doi.org/10.1096/fasebj.2021.35.s1.01955
https://doi.org/10.1096/fasebj.2021.35.s1.01955