Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Keisuke Fukutomi"'
Autor:
Kazuhiro Murai, Takahiro Kodama, Hayato Hikita, Akiyoshi Shimoda, Makoto Fukuoka, Keisuke Fukutomi, Satoshi Shigeno, Yuto Shiode, Daisuke Motooka, Yuichiro Higuchi, Kei Miyakawa, Hiroshi Suemizu, Akihide Ryo, Yuki Tahata, Yuki Makino, Ryoko Yamada, Ryotaro Sakamori, Tomohide Tatsumi, Tetsuo Takehara
Publikováno v:
Hepatology Communications, Vol 6, Iss 9, Pp 2474-2487 (2022)
Abstract Current anti–hepatitis B virus (HBV) therapies have little effect on covalently closed circular DNA (cccDNA) and fail to eliminate HBV. The clustered regularly interspaced short palindromic repeat (CRISPR)/Cas9 system has been reported to
Externí odkaz:
https://doaj.org/article/ca7f46ce603c4fe5827dd0ed21bcf508
Autor:
Keisuke Fukutomi, Hayato Hikita, Kazuhiro Murai, Tasuku Nakabori, Akiyoshi Shimoda, Makoto Fukuoka, Takuo Yamai, Yuichiro Higuchi, Kei Miyakawa, Hiroshi Suemizu, Akihide Ryo, Ryoko Yamada, Takahiro Kodama, Ryotaro Sakamori, Tomohide Tatsumi, Tetsuo Takehara
Publikováno v:
Hepatology Communications, Vol 6, Iss 2, Pp 281-296 (2022)
Capsid allosteric modulators (CAMs) inhibit the encapsidation of hepatitis B virus (HBV) pregenomic RNA (pgRNA), which contains a pathogen‐associated molecular pattern motif. However, the effect of CAMs on the innate immune response of HBV‐infect
Externí odkaz:
https://doaj.org/article/ddbf93e2908e4cb2a4bdd336a3d8debe
Autor:
Akiyoshi Shimoda, Takuo Yamai, Tasuku Nakabori, Takahiro Kodama, Makoto Fukuoka, Yuichiro Higuchi, Kei Miyakawa, Akihide Ryo, Hayato Hikita, Ryoko Yamada, Tetsuo Takehara, Tomohide Tatsumi, Ryotaro Sakamori, Keisuke Fukutomi, Hiroshi Suemizu, Kazuhiro Murai
Publikováno v:
Hepatology Communications, Vol 6, Iss 2, Pp 281-296 (2022)
Hepatology Communications
Hepatology Communications
Capsid allosteric modulators (CAMs) inhibit the encapsidation of hepatitis B virus (HBV) pregenomic RNA (pgRNA), which contains a pathogen-associated molecular pattern motif. However, the effect of CAMs on the innate immune response of HBV-infected h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66267b9d7c4c4b05e3057e5f0d3e2e23
https://doaj.org/article/ddbf93e2908e4cb2a4bdd336a3d8debe
https://doaj.org/article/ddbf93e2908e4cb2a4bdd336a3d8debe
Autor:
Takahiro Kodama, Tasuku Nakabori, Tomohide Tatsumi, Keisuke Fukutomi, Takuo Yamai, Kazuhiro Murai, Ryotaro Sakamori, Ryoko Yamada, Hayato Hikita, Kei Miyakawa, Akihide Ryo, Makoto Fukuoka, Tetsuo Takehara, Kohei Watashi
Publikováno v:
Biochemical and Biophysical Research Communications. 527:64-70
Autophagy is an intracellular process that can lead to the degradation of malfunctioned proteins and damaged organelles to maintain homeostasis during cellular stress. Here, we evaluated the change in hepatitis B virus (HBV) production by regulating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8268ca111a1d81c173ae0890237d40c8
https://doi.org/10.1016/j.bbrc.2020.04.031
https://doi.org/10.1016/j.bbrc.2020.04.031
Autor:
Takahiro Kodama, Ryo Fukuda, Ryoko Yamada, Kazuhiro Murai, Tetsuo Takehara, Yasuteru Kondo, Takeshi Takahashi, Keisuke Fukutomi, Tomohide Tatsumi, Hayato Hikita, Kei Miyakawa, Akira Doi, Hiroshi Suemizu, Takuo Yamai, Ryotaro Sakamori, Akihide Ryo, Makoto Fukuoka, Yugo Kai, Tasuku Nakabori
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Mechanisms of hepatitis B virus (HBV) reactivation after hepatitis C virus (HCV) elimination by direct-acting antiviral (DAA) treatment in HBV/HCV-co-infected patients remain unclear. We examined RIG-I-like helicase (RLH) pathway activation by HBV mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31b8b9ffabb107ae02adac346fc22862
https://doi.org/10.1038/s41598-020-57603-9
https://doi.org/10.1038/s41598-020-57603-9
Autor:
Takahiro Kodama, Ryoko Yamada, Takayuki Yakushijin, Eiichi Morii, Ryotaro Sakamori, Tetsuo Takehara, Keisuke Fukutomi, Hayato Hikita, Minoru Shigekawa, Keiichiro Honma, Kunimaro Furuta, Tomohide Tatsumi
Publikováno v:
Kanzo. 58:519-527
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85d71b4c4ab817d9317a05dc5bfd482a
https://doi.org/10.2957/kanzo.58.519
https://doi.org/10.2957/kanzo.58.519
Autor:
Kunio Suzuki, Takahiro Kodama, Tomohide Tatsumi, Kunimaro Furuta, Hayato Hikita, Ryoko Yamada, Tetsuo Takehara, Minoru Shigekawa, Ryotaro Sakamori, Keisuke Fukutomi, Takayuki Yakushijin, Tohru Sanada
Publikováno v:
Kanzo. 58:393-400
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0109516ccb285ac8a3103f66eb46a1b
https://doi.org/10.2957/kanzo.58.393
https://doi.org/10.2957/kanzo.58.393
Autor:
Akira Nishio, Tomohide Tatsumi, Takeshi Takahashi, Yoshiki Onishi, Satoshi Aono, Takahiro Kodama, Seiichi Tawara, Ryotaro Sakamori, Minoru Shigekawa, Keisuke Fukutomi, Teppei Yoshioka, Hiroshi Suemizu, Tetsuo Takehara, Tasuku Nakabori, Hayato Hikita
Publikováno v:
Biochemical and biophysical research communications. 503(3)
It is well known that immune-mediated virus elimination is necessary for the treatment of HBV infection. Reconstitution of human immune cells in liver chimeric mice is warranted to understand the immunopathogenesis of HBV infection. Here, we report a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d8b669e5a21b2e720efdd8293060775
https://pubmed.ncbi.nlm.nih.gov/30033102
https://pubmed.ncbi.nlm.nih.gov/30033102
Autor:
Shigeki, Matsuda, Yasufumi, Takemoto, Takashi, Taguchi, Takayoshi, Ishihara, Keisuke, Fukutomi
Publikováno v:
岐阜聖徳学園大学短期大学部紀要 = Bulletin of Gifu Shotoku Gakuen University Junior College. 46:51-56
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=jairo_______::86d446e00100e9d2ea4ad997bcbafc3f
http://id.nii.ac.jp/1550/00000427/
http://id.nii.ac.jp/1550/00000427/
Autor:
Hisashi Ishida, Tetsuya Iwasaki, Takashi Toyama, Sadatsugu Sakane, Keiichi Kimura, Shoichi Nakazuru, Keisuke Fukutomi, Aya Sugimoto, Takuya Yamada, Yuko Sakakibara, Ryuichiro Iwasaki, Takeshi Tamura, Hiroko Hasegawa, Eiji Mita, Kenji Hibino
Publikováno v:
Hepatology Research. 44:E84-E91
Aim Anemia frequently develops in patients given pegylated interferon, ribavirin (RBV), telaprevir (TVR) triple therapy and restricts treatment by forcing reduction or discontinuation of RBV administration. We investigated whether erythropoietin (EPO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::603f65415c9fd5504da03a1451ec0d1a
https://doi.org/10.1111/hepr.12224
https://doi.org/10.1111/hepr.12224