Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Keisuke Akagi"'
Autor:
Yoshikazu Nagashima, Dai Watanabe, Yuko Yamaguchi, Hiroyasu Yoshikawa, Hiromi Nakara, Azusa Okaniwa, Keisuke Akagi, Toru Hoshiya
Publikováno v:
Journal of Toxicologic Pathology. 17:187-195
Beagle dogs intravenously treated with alloxan monohydrate at 50 mg/kg and kept for 14 months were subjected to clinicopathological and histopathological examinations in order to characterize the development of diabetic changes. The beagle model of d
Publikováno v:
Toxicologic Pathology. 31:388-396
Phenethyl isothiocyanate (PEITC)1 and benzyl isothiocyanate (BITC), naturally occurring constituents of cruciferous vegetables, have been reported to exert inhibitory effects against development of tobacco-specific carcinogen-induced lung tumors and
Autor:
Keisuke Akagi, Masao Hirose, Mitsuru Futakuchi, Tomoyuki Shirai, Yasumoto Mizoguchi, Tsuyoshi Yamaguchi
Publikováno v:
Cancer Letters. 188:163-170
Differences in the modifying effects of green tea catechins (GTC) on intestinal carcinogenesis by different formulations, doses and administration routes were investigated in male rats pretreated with 1,2-dimethylhydrazine (DMH). One hundred and eigh
Autor:
Atsushi Nakamura, Yasumoto Mizoguchi, Tomoyuki Shirai, Masao Hirose, Keisuke Akagi, Toru Hoshiya
Publikováno v:
Cancer Letters. 168:23-29
Modifying effects of green tea catechins (GTCs) on the post-initiation stage of colon, lung and thyroid carcinogenesis were examined in F344 male rats. Groups of 20 animals were given subcutaneous injections of 40 mg/kg body wt of 1,2-dimethylhydrazi
Autor:
Hideo Kaneko, Keisuke Akagi, Tomoyuki Shirai, Koichi Saito, Kazuo Hakoi, Satoru Takahashi, Masao Hirose, Cui Lin, Toru Hoshiya
Publikováno v:
Toxicologic Pathology. 27:448-455
Histogenesis and mechanisms of catechol-induced rat glandular stomach carcinogenesis were investigated in male F344 rats. Groups of 5 or 6 rats were treated with dietary catechol at doses of 1, 0.5, 0.1, and 0.01% for 12 hr or for 1, 2, 3, or 7 days
Autor:
Kaoru Inoue, Takahiro Ishii, Keisuke Akagi, Hiroyuki Mizuno, Kazutoshi Tamura, Makoto Ide, Kazunori Shimamura
Publikováno v:
The Journal of Toxicological Sciences. 23:37-49
A 2-week toxicity study of magnesium sulfate administered by a 24-hr intravenous infusion at the dosage levels of 0, 12.5, 50, 100 and 200 mg/kg/hr in female beagle dogs was conducted, with 2-week follow-up observation after drug withdrawal. One of 2
Autor:
Satoru Takahashi, Keisuke Akagi, Tomoyuki Shirai, Tadashi Ogiso, Mitsuo Kurata, Juki Kimura, Yasunori Yoshida, Masao Hirose, Ryohei Hasegawa
Publikováno v:
Japanese Journal of Cancer Research : Gann
Modifying effects of dietary administration of the monoterpene d-limonene were examined using a multi-organ carcinogenesis model. Groups of twenty F344 male rats were treated sequentially with N-diethylnitrosamine (DEN, i.p.), N-methyl-N-nitrosourea
Publikováno v:
Cancer Letters. 94:113-121
Effects of dietary supplementation with the antioxidants ellagic acid, quercetin and vanillin were examined using a medium term multi-organ carcinogenesis model in rats. Groups of 10-15 male F344 rats were given i.p. injections of diethylnitrosamine
Autor:
Ryohei Hasegawa, Tomoyuki Shirai, Keisuke Akagi, Juki Kimura, Tokutaro Miki, Masao Hirose, Nobuyuki Ito, Keiji Wakabayashi, Toshio Satoh, Hikaru Tanaka, Yasunori Yoshida
Publikováno v:
Carcinogenesis. 16:3049-3055
The effects of 1-O-hexyl-2,3,5-trimethylhydroquinone (HTHQ), green tea catechins (GTC), alpha-tocopherol, beta-carotene, chlorophyllin, phenylethylisothiocyanate (PEITC), 3-O-ethylascorbic acid (EAsA), 3-O-dodecylcarbomethyl ascorbic acid (DAsA), n-t
Autor:
Toshio Satoh, Ryohei Hasegawa, Yukihiko Hara, Masao Hirose, Nobuyuki Ito, Makoto Yaono, Keisuke Akagi, Keiji Wakabayashi
Publikováno v:
Carcinogenesis. 16:217-221
Chemopreventive effects of the antioxidants 1-O-hexyl-2,3,5- trimethylhydroquinone (HTHQ), 3-O-ethylascorbic acid (EAsA), 3-O-dodecylcarbomethylascorbic acid (DAsA), green tea catechins (GTC) and ellagic acid on 2-amino-1-methyl-6- phenylimidazo[4,5-