Zobrazeno 1 - 10
of 121
pro vyhledávání: '"Keisuke Ae"'
Autor:
Miwa Tanaka, Surachada Chuaychob, Mizuki Homme, Yukari Yamazaki, Ruyin Lyu, Kyoko Yamashita, Keisuke Ae, Seiichi Matsumoto, Kohei Kumegawa, Reo Maruyama, Wei Qu, Yohei Miyagi, Ryuji Yokokawa, Takuro Nakamura
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
The mechanisms of angiogenesis in alveolar soft part sarcoma (ASPS) remain to be explored. Here, the authors highlight the role of the ASPSCR1::TFE3 fusion in regulating super-enhancer activity during the angiogenic process in ASPS.
Externí odkaz:
https://doaj.org/article/f50b7143e44a43cdb1e1c9081c28b300
Autor:
Akihiro Ohmoto, Kenji Nakano, Naoki Fukuda, Xiaofei Wang, Tetsuya Urasaki, Naomi Hayashi, Hirotaka Suto, Shohei Udagawa, Ryosuke Oki, Yasuyoshi Sato, Mayu Yunokawa, Makiko Ono, Masanori Saito, Yusuke Minami, Keiko Hayakawa, Taisuke Tanizawa, Keisuke Ae, Seiichi Matsumoto, Junichi Tomomatsu, Shunji Takahashi
Publikováno v:
PLoS ONE, Vol 18, Iss 3 (2023)
Trabectedin is a therapeutic option for patients with advanced sarcoma. While a randomized trial demonstrated its prolonged progression-free survival (PFS), the reported PFS was 1 year). The ORR in the 49 evaluable patients was 8%, and the median PFS
Externí odkaz:
https://doaj.org/article/1ad98d3f83ec4a80b58fa31dacaacb84
Autor:
Yoshiya Sugiura, Rikuo Machinami, Seiichi Matsumoto, Hiroaki Kanda, Keisuke Ae, Yutaka Takazawa, Kengo Takeuchi
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract It is controversial whether patients with myxofibrosarcomas (MFSs) have better prognoses than those with undifferentiated pleomorphic sarcomas (UPSs). No useful prognostic factors have been established to date. We therefore aimed to evaluate
Externí odkaz:
https://doaj.org/article/304e61aea03045d886ea85f967be7160
Autor:
Munehisa Kito, Keisuke Ae, Masanori Okamoto, Makoto Endo, Kunihiro Ikuta, Akihiko Takeuchi, Naohiro Yasuda, Taketoshi Yasuda, Yoshinori Imura, Takeshi Morii, Kazutaka Kikuta, Teruya Kawamoto, Yutaka Nezu, Ichiro Baba, Shusa Ohshika, Takeshi Uehara, Takafumi Ueda, Jun Takahashi, Hirotaka Kawano
Publikováno v:
Cancers, Vol 15, Iss 8, p 2314 (2023)
This retrospective multicenter study aimed to analyze the clinical features and prognosis of 24 patients diagnosed with LGMS between 2002 and 2019 in the Japanese sarcoma network. Twenty-two cases were surgically treated and two cases were treated wi
Externí odkaz:
https://doaj.org/article/142b7e4009384f9f916fdbbb4fb79898
Autor:
Keiko Hayakawa, Seiichi Matsumoto, Keisuke Ae, Taisuke Tanizawa, Yuki Funauchi, Yusuke Minami, Masanori Saito, Atsushi Okawa
Publikováno v:
Journal of Orthopaedics and Traumatology, Vol 21, Iss 1, Pp 1-10 (2020)
Abstract Background Recently, the number of osteosarcomas in middle-aged and older patients has demonstrated an increasing trend; moreover, their results are comparatively worse than those of young patients. In Europe and the USA, the prognosis for o
Externí odkaz:
https://doaj.org/article/b02466ecf578440691fff833d1d8fd77
Autor:
Kazuhiro Tanaka, Junki Mizusawa, Norifumi Naka, Akira Kawai, Hirohisa Katagiri, Toru Hiruma, Yoshihiro Matsumoto, Hiroyuki Tsuchiya, Robert Nakayama, Hiroshi Hatano, Makoto Emori, Munenori Watanuki, Yukihiro Yoshida, Takeshi Okamoto, Satoshi Abe, Kunihiro Asanuma, Ryohei Yokoyama, Hiroaki Hiraga, Tsukasa Yonemoto, Takeshi Morii, Keisuke Ae, Akihito Nagano, Hideki Yoshikawa, Haruhiko Fukuda, Toshifumi Ozaki, Yukihide Iwamoto
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-7 (2019)
Abstract Background Soft-tissue sarcomas (STS) are rare malignant tumors those are resistant to chemotherapy. We have previously reported the 3-year follow-up result on the efficacy of perioperative chemotherapy with doxorubicin (DXR) and ifosfamide
Externí odkaz:
https://doaj.org/article/d31afd75fc504fdeb97c20cf9778e057
Autor:
Keiko Hayakawa, Seiichi Matsumoto, Keisuke Ae, Taisuke Tanizawa, Yuki Funauchi, Yusuke Minami, Masanori Saito
Publikováno v:
Foot & Ankle Surgery: Techniques, Reports & Cases, Vol 1, Iss 4, Pp 100096- (2021)
Combined limb salvage surgery and radiation therapy has been gaining traction for the treatment of soft tissue sarcomas of the foot in recent years. However, limb salvage surgery without radiation therapy is more desirable. In this study, we obtained
Externí odkaz:
https://doaj.org/article/d75ce7e7970a49a7906bd36ab1d2d87c
Autor:
Yasuyoshi Sato, Kenji Nakano, Xiaofei Wang, Naoki Fukuda, Tetsuya Urasaki, Akihiro Ohmoto, Naomi Hayashi, Mayu Yunokawa, Makiko Ono, Junichi Tomomatsu, Masanori Saito, Yusuke Minami, Keiko Hayakawa, Yuki Funauchi, Taisuke Tanizawa, Keisuke Ae, Seiichi Matsumoto, Shunji Takahashi
Publikováno v:
Cancers, Vol 13, Iss 24, p 6266 (2021)
Pazopanib with trabectedin and eribulin is widely used to treat soft-tissue sarcoma (STS). We have shown that baseline neutrophil-to-lymphocyte ratio (NLR) may predict the efficacy and patient prognosis of eribulin. Changes in NLR, but not baseline N
Externí odkaz:
https://doaj.org/article/cac8de16c1964cd4b568fc363dd45969
Autor:
Yasuyo Teramura, Miwa Tanaka, Yukari Yamazaki, Kyoko Yamashita, Yutaka Takazawa, Keisuke Ae, Seiichi Matsumoto, Takayuki Nakayama, Takao Kaneko, Yoshiro Musha, Takuro Nakamura
Publikováno v:
Cancers, Vol 12, Iss 9, p 2345 (2020)
Fusion genes induced by chromosomal aberrations are common mutations causally associated with bone and soft tissue sarcomas (BSTS). These fusions are usually disease type-specific, and identification of the fusion genes greatly helps in making precis
Externí odkaz:
https://doaj.org/article/173d44524adb452d87dd5418422b2dc1
Autor:
Miwa Tanaka, Mizuki Homme, Yukari Yamazaki, Keisuke Ae, Seiichi Matsumoto, Subbaya Subramanian, Takuro Nakamura
Publikováno v:
Cancers, Vol 12, Iss 2, p 324 (2020)
SS18-SSX fusion proteins play a central role in synovial sarcoma development, although, the genetic network and mechanisms of synovial sarcomagenesis remain unknown. We established a new ex vivo synovial sarcoma mouse model through retroviral-mediate
Externí odkaz:
https://doaj.org/article/f02018a54937488fa0bb1a18910064f0