Zobrazeno 1 - 10
of 281
pro vyhledávání: '"Keisuke, S."'
Autor:
Jiang, Lu, Xu, Di, Xu, Qifan, Chatziioannou, Arion, Iwamoto, Keisuke S., Hui, Susanta, Sheng, Ke
Image-guided mouse irradiation is essential to understand interventions involving radiation prior to human studies. Our objective is to employ Swin UNEt Transformers (Swin UNETR) to segment native micro-CT and contrast-enhanced micro-CT scans and ben
Externí odkaz:
http://arxiv.org/abs/2405.18676
Autor:
Prabhat K. Purbey, Joowon Seo, Manash K. Paul, Keisuke S. Iwamoto, Allison E. Daly, An-Chieh Feng, Ameya S. Champhekar, Justin Langerman, Katie M. Campbell, Dörthe Schaue, William H. McBride, Steven M. Dubinett, Antoni Ribas, Stephen T. Smale, Philip O. Scumpia
Publikováno v:
Cell Reports, Vol 43, Iss 6, Pp 114289- (2024)
Summary: Type I interferon (IFN-I) and IFN-γ foster antitumor immunity by facilitating T cell responses. Paradoxically, IFNs may promote T cell exhaustion by activating immune checkpoints. The downstream regulators of these disparate responses are i
Externí odkaz:
https://doaj.org/article/1aacdb1bc8d04f2aac55bcac0e7d97b6
Autor:
Purbey, Prabhat K., Seo, Joowon, Paul, Manash K., Iwamoto, Keisuke S., Daly, Allison E., Feng, An-Chieh, Champhekar, Ameya S., Langerman, Justin, Campbell, Katie M., Schaue, Dörthe, McBride, William H., Dubinett, Steven M., Ribas, Antoni, Smale, Stephen T., Scumpia, Philip O.
Publikováno v:
In Cell Reports 25 June 2024 43(6)
Autor:
Chenyang Wang, MD, PhD, Amar U. Kishan, MD, James B. Yu, MD, MHS, Ann Raldow, MD, MPH, Christopher R. King, MD, PhD, Keisuke S. Iwamoto, PhD, Fang-I. Chu, PhD, Michael L. Steinberg, MD, Patrick A. Kupelian, MD
Publikováno v:
Advances in Radiation Oncology, Vol 4, Iss 4, Pp 738-747 (2019)
Purpose: Second malignancies (SMs) after radiation therapy are rare but serious sequelae of treatment. This study investigates whether radiation therapy use is associated with changes in baseline SM risk. Methods and Materials: We extracted all patie
Externí odkaz:
https://doaj.org/article/f7fd2e1cc5dd4ee88af217163b86465e
Autor:
Dörthe Schaue, Ewa D. Micewicz, Josephine A. Ratikan, Keisuke S. Iwamoto, Erina Vlashi, J. Tyson McDonald, William H. McBride
Publikováno v:
Antioxidants, Vol 11, Iss 9, p 1649 (2022)
Nuclear factor erythroid 2-related factor 2 (NRF2) is recognized as a master transcription factor that regulates expression of numerous detoxifying and antioxidant cytoprotective genes. In fact, models of NRF2 deficiency indicate roles not only in re
Externí odkaz:
https://doaj.org/article/d93c14d74c3a4a43a4f52aa740921de6
Autor:
Ewa D. Micewicz, Robert D. Damoiseaux, Gang Deng, Adrian Gomez, Keisuke S. Iwamoto, Michael E. Jung, Christine Nguyen, Andrew J. Norris, Josephine A. Ratikan, Piotr Ruchala, James W. Sayre, Dörthe Schaue, Julian P. Whitelegge, William H. McBride
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
We previously reported several vignettes on types and classes of drugs able to mitigate acute and, in at least one case, late radiation syndromes in mice. Most of these had emerged from high throughput screening (HTS) of bioactive and chemical drug l
Externí odkaz:
https://doaj.org/article/51771cf263924ecca3296a531a0d3deb
Autor:
Keisuke S. Iwamoto, PhD, Robert E. Sandstrom, MD, Mark Bryan, EdM, Yue Liu, PhD, S. Robin Elgart, PhD, Ke Sheng, PhD, Michael L. Steinberg, MD, William H. McBride, DSc, Daniel A. Low, PhD
Publikováno v:
Advances in Radiation Oncology, Vol 6, Iss 3, Pp 100645- (2021)
Purpose: The clinical efficacy of radiation therapy is mechanistically linked to ionization-induced free radicals that cause cell and tissue injury through direct and indirect mechanisms. Free radical reaction dynamics are influenced by many factors
Externí odkaz:
https://doaj.org/article/09bd2ef75e0c48eaba3967ae6c9af553
Publikováno v:
Radiation Research, 2006 Dec 01. 166(6), 870-876.
Externí odkaz:
https://www.jstor.org/stable/4098735
Publikováno v:
Radiation Research, 2006 May 01. 165(5), 616-620.
Externí odkaz:
https://www.jstor.org/stable/3581431
Autor:
Claude J Rogers, Agnes I Lukaszewicz, Jason Yamada-Hanff, Ewa D Micewicz, Josephine A Ratikan, Mark A Starbird, Thomas A Miller, Christine Nguyen, Jason T Lee, Tove Olafsen, Keisuke S Iwamoto, William H McBride, Dörthe Schaue, Naresh Menon
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0232411 (2020)
Acute radiation exposure of the thorax can lead to late serious, and even life-threatening, pulmonary and cardiac damage. Sporadic in nature, late complications tend to be difficult to predict, which prompted this investigation into identifying non-i
Externí odkaz:
https://doaj.org/article/9ef236df45954e98bbb80c111b9106d1