Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Keisuke, KAJITA"'
Autor:
Keisuke Kajita, Mitsuhiro Nishida, Yasuo Kurimoto, Satoshi Yokota, Sunao Sugita, Toshika Semba, Satoshi Shirae, Naoko Hayashi, Atsuta Ozaki, Yoko Miura, Akiko Maeda, Yoshinori Mitamura, Masayo Takahashi, Michiko Mandai
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Clinical studies using suspensions or sheets of human pluripotent cell-derived retinal pigment epithelial cells (hiPSC-RPE) have been conducted globally for diseases such as age-related macular degeneration. Despite being minimally invasive,
Externí odkaz:
https://doaj.org/article/26120f46828443c895e578fe70a4d701
Autor:
Shohei Kitahata, Michiko Mandai, Hinako Ichikawa, Yuji Tanaka, Toshika Senba, Keisuke Kajita, Sunao Sugita, Kazuaki Kadonosono, Masayo Takahashi
Publikováno v:
Regenerative Therapy, Vol 25, Iss , Pp 238-249 (2024)
Introduction: The retinal pigment epithelium (RPE) plays essential roles in maintaining retinal functions as well as choroidal capillaries and can lead to visual disorders if dysfunctional. Transplantation of human-induced pluripotent stem cell-deriv
Externí odkaz:
https://doaj.org/article/07ab9e110ef742229cde3e1c477d1da7
Publikováno v:
Case Reports in Ophthalmology, Vol 12, Iss 3, Pp 952-960 (2021)
Nivolumab and ipilimumab are widely used immune checkpoint inhibitors (ICPIs) for the treatment of metastatic melanoma. ICPIs cause an array of side effects called immune-related adverse events (IRAEs) due to activation of an immune response. ICPI-uv
Externí odkaz:
https://doaj.org/article/bdda95afbe8143d7ab45e5aea2cdd0ce
Autor:
Azusa, ISHIGURO, Kazuyuki, KOBAYASHI, Takaaki, WATANABE, Tomomi, HASEGAWA, Keisuke, KAJITA, Yuko, TAMAKI
Publikováno v:
鶴見大学紀要. 第3部, 保育・歯科衛生編 = The bulletin of Tsurumi University. Pt. 3, Studies in infant education and dental hygiene. 57:79-84
Autor:
Kazuyuki, KOBAYASHI, Takaaki, WATANABE, Tomomi, HASEGAWA, Miho, SHINOHARA, Keisuke, KAJITA, Azusa, ISHIGURO, Yuko, TAMAKI
Publikováno v:
鶴見大学紀要. 第3部, 保育・歯科衛生編 = The bulletin of Tsurumi University. Pt. 3, Studies in infant education and dental hygiene. 56:5-11
Autor:
Kensei Nishida, Kiyoshi Masuda, Keisuke Kajita, Yuki Kuwano, Kazuhito Rokutan, Ken Kurokawa, Yoko Akaike, Shizuka Kano
Publikováno v:
Oncogene. 34:3463-3473
Homeodomain-interacting protein kinase 2 (HIPK2) is a potential tumor suppressor that has a crucial role in the DNA damage response (DDR) by regulating cell-cycle checkpoint activation and apoptosis. However, it is unclear whether HIPK2 exerts distin
Autor:
Kazuhito Rokutan, Ken Kurokawa, Keisuke Kajita, Yuki Kuwano, Issei Imoto, Yuzuru Satake, Kensei Nishida, Kiyoshi Masuda, Yoko Akaike, Katsutoshi Shoda
Publikováno v:
Molecular and Cellular Biology. 34:2857-2873
Hu antigen R (HuR) regulates stress responses through stabilizing and/or facilitating the translation of target mRNAs. The human TRA2β gene encodes splicing factor transformer 2β (Tra2β) and generates 5 mRNA isoforms (TRA2β1 to -5) through altern
Autor:
Kiyoshi Masuda, Kensei Nishida, Keisuke Kajita, Toshihito Tanahashi, Kazuhito Rokutan, Yuki Kuwano, Ken Kurokawa, Naoko Yamagishi, Yoko Akaike
Publikováno v:
Oncogene. 33:1407-1417
Serine/arginine-rich splicing factor 3 (SRSF3) likely has wide-ranging roles in gene expression and facilitation of tumor cell growth. SRSF3 knockdown induced G1 arrest and apoptosis in colon cancer cells (HCT116) in association with altered expressi
Autor:
Yoko Akaike, Manami Honda, Naruka Kitamura, Kensei Nishida, Kiyoshi Masuda, Yuzuru Satake, Keisuke Kajita, Kazuhito Rokutan, Ken Kurokawa, Yuki Kuwano
Publikováno v:
Journal of Gastroenterology. 48:1222-1233
Transformer (Tra) 2β is a member of the serine/arginine-rich (SR)-like protein family that regulates alternative splicing of numerous genes in a concentration-dependent manner. Several types of cancer cells up-regulate Tra2β expression, while the r
Autor:
Yuki Kuwano, Kazuhito Rokutan, Yoko Akaike, Kensei Nishida, Keisuke Kajita, Ken Kurokawa, Shizuka Kano, Kiyoshi Masuda, Toshihito Tanahashi, Chihiro Nishiyama
Publikováno v:
The Journal of Medical Investigation. 60:228-235
Serine/arginine-rich splicing factor 3 (SRSF3), a member of the SRSF family, plays a wide-ranging role in gene expression. The human SRSF3 gene generates a major mRNA isoform encoding a functional, full-length protein and a PTC-containing isoform (SR