Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Keishi Otsu"'
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Tooth development is governed largely by epithelial–mesenchymal interactions and is mediated by numerous signaling pathways. This type of morphogenetic processes has been explained by reaction–diffusion systems, especially in the framewo
Externí odkaz:
https://doaj.org/article/cf1106d3a6504613a2ae56d4dfdd2c26
Autor:
Haruno Arai, Akira Inaba, Shojiro Ikezaki, Mika Kumakami-Sakano, Marii Azumane, Hayato Ohshima, Kazumasa Morikawa, Hidemitsu Harada, Keishi Otsu
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Maturation stage ameloblasts (M-ABs) are responsible for terminal enamel mineralization in teeth and undergo characteristic cyclic changes in both morphology and function between ruffle-ended ameloblasts (RA) and smooth-ended ameloblasts (SA). Energy
Externí odkaz:
https://doaj.org/article/7e253a74d0184e6c95cb08038add5c0f
Autor:
Shinichi Ishiguro, Tetsuro Shinada, Zhou Wu, Mayumi Karimazawa, Michimasa Uchidate, Eiji Nishimura, Yoko Yasuno, Makiko Ebata, Piyamas Sillapakong, Hiromi Ishiguro, Nobuyoshi Ebata, Junjun Ni, Muzhou Jiang, Masanobu Goryo, Keishi Otsu, Hidemitsu Harada, Koichi Suzuki
Publikováno v:
PLoS ONE, Vol 16, Iss 1, p e0245235 (2021)
The use of agents that target both glia and neurons may represent a new strategy for the treatment of ageing disorders. Here, we confirmed the presence of the novel cyclic peptide Naturido that originates from a medicinal fungus (Isaria japonica) gro
Externí odkaz:
https://doaj.org/article/1093fdd724644c2d8cd273661461c6a9
Autor:
Keishi Otsu, Hidemitsu Harada
Publikováno v:
Japanese Dental Science Review, Vol 52, Iss 2, Pp 32-40 (2016)
During tooth development, ameloblasts differentiate from inner enamel epithelial cells to enamel-forming cells by modulating the signal pathways mediating epithelial–mesenchymal interaction and a cell-autonomous gene network. The differentiation pr
Externí odkaz:
https://doaj.org/article/5e5848891fd5417680e46730cffa5f1a
Publikováno v:
Journal of Oral Biosciences. 65:47-54
Autor:
Marii Azumane, Shojiro Ikezaki, Keishi Otsu, Mika Kumakami‐Sakano, Haruno Arai, Hiroyuki Yamada, Päivi Kettunen, Hidemitsu Harada
Publikováno v:
Journal of Periodontal Research. 58:184-194
Hertwig's epithelial root sheath (HERS) plays a role in root dentin formation. It produces the epithelial rests of Malassez (ERM) for the induction of periodontal tissue development during root formation. Although ERM is thought to be caused by epith
Autor:
Akira Inaba, Hidemitsu Harada, Shojiro Ikezaki, Mika Kumakami-Sakano, Haruno Arai, Marii Azumane, Hayato Ohshima, Kazumasa Morikawa, Kuniyuki Kano, Junken Aoki, Keishi Otsu
Publikováno v:
Journal of Oral Biosciences. 64:85-92
Autor:
Shujin Li, Hyun‐Yi Kim, Dong‐Joon Lee, Sung‐Ho Park, Keishi Otsu, Hidemitsu Harada, Young‐Soo Jung, Han‐Sung Jung
Publikováno v:
Cell Proliferation. 55
Autor:
Masaaki Matsuura, Honami Yonezawa, Naoyuki Nishiya, Tomoko Sakyo, Shingo Dan, Tsutomu Fukuda, Masatomo Iwao, Yusuke Oku, Fumito Ishibashi, Yoko Furukawa, Yuka Sasaki, Takao Yamori, Masaru Ushijima, Yoshimasa Uehara, Tetsuo Mashima, Hiroyuki Seimiya, Akihiro Tomida, Chie Ishikawa, Keishi Otsu, Masanori Abe
Publikováno v:
Cancer Science
The emergence of acquired resistance is a major concern associated with molecularly targeted kinase inhibitors. The C797S mutation in the epidermal growth factor receptor (EGFR) confers resistance to osimertinib, a third‐generation EGFR‐tyrosine
Autor:
Yuriko Maruya, Tsutomu Iwamoto, Hidemistu Harada, Aya Yamada, Keishi Otsu, Keigo Yoshizaki, Ryoko Hino, Kan Saito, Satoshi Fukumoto, Emiko Fukumoto, Yuta Chiba
Publikováno v:
Pediatric Dental Journal. 30:208-214
Background Filamin-A (FLNA) is one of the adaptor proteins binding to both integrin beta chain and actin filament. Several kind of mutation in human FLNA gene were observed in Melnick-Needles syndrome (MNS). However, the role of FLNA in tooth formati